Search Results - "Sergey V. Sennikov"

T-helper cells flexibility: the possibility of reprogramming T cells fate by Khantakova, Julia N, Sennikov, Sergey V

“…Various disciplines cooperate to find novel approaches to cure impaired body functions by repairing, replacing, or regenerating cells, tissues, or organs. The…”
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Immunoregulatory properties of erythroid nucleated cells induced from CD34+ progenitors from bone marrow by Shevchenko, Julia A, Perik-Zavodskii, Roman Yu, Nazarov, Kirill V, Denisova, Vera V, Perik-Zavodskaya, Olga Yu, Philippova, Yulia G, Alsalloum, Alaa, Sennikov, Sergey V

“…CD 71+ erythroid nucleated cells have pronounced immunoregulatory properties in normal and pathological conditions. Many populations of cells with…”
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TCR-T cell therapy: current development approaches, preclinical evaluation, and perspectives on regulatory challenges by Golikova, Elena A, Alshevskaya, Alina A, Alrhmoun, Saleh, Sivitskaya, Natalia A, Sennikov, Sergey V

“…TCR-T cell therapy represents a promising advancement in adoptive immunotherapy for cancer treatment. Despite its potential, the development and preclinical…”
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Erythroid Cells as Full Participants in the Tumor Microenvironment by Shevchenko, Julia A, Nazarov, Kirill V, Alshevskaya, Alina A, Sennikov, Sergey V

“…The tumor microenvironment is an important factor that can determine the success or failure of antitumor therapy. Cells of hematopoietic origin are one of the…”
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The Regulatory-T-Cell Memory Phenotype: What We Know by Khantakova, Julia N, Bulygin, Aleksey S, Sennikov, Sergey V

“…In immunology, the discovery of regulatory T (Treg) cells was a major breakthrough. Treg cells play a key role in pregnancy maintenance, in the prevention of…”
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Dendritic cells transfected with DNA constructs encoding CCR9, IL-10, and type II collagen demonstrate induction of immunological tolerance in an arthritis model by Fisher, Marina S, Kurilin, Vasily V, Bulygin, Aleksey S, Shevchenko, Julia A, Philippova, Julia G, Taranov, Oleg S, Ivleva, Elena K, Maksyutov, Amir Z, Sennikov, Sergey V

“…Restoring immune tolerance is a promising area of therapy for autoimmune diseases. One method that helps restore immunological tolerance is the approach using…”
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Co-Expression Profile of TNF Membrane-Bound Receptors Type 1 and 2 in Rheumatoid Arthritis on Immunocompetent Cells Subsets by Alshevskaya, Alina, Lopatnikova, Julia, Zhukova, Julia, Chumasova, Oksana, Shkaruba, Nadezhda, Sizikov, Aleksey, Evsegneeva, Irina, Gladkikh, Victor, Karaulov, Aleksander, Sennikov, Sergey V

“…Tumor necrosis factor (TNFα) is an important proinflammatory cytokine in rheumatoid arthritis (RA) immune processes. However, TNFα activity and functions may…”
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Prophylactic Dendritic Cell-Based Vaccines Efficiently Inhibit Metastases in Murine Metastatic Melanoma by Markov, Oleg V, Mironova, Nadezhda L, Sennikov, Sergey V, Vlassov, Valentin V, Zenkova, Marina A

“…Recent data on the application of dendritic cells (DCs) as anti-tumor vaccines has shown their great potential in therapy and prophylaxis of cancer. Here we…”
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Autoantibodies to Tumor Necrosis Factor in Patients with Active Pulmonary Tuberculosis by Kireev, Fedor D, Lopatnikova, Julia A, Laushkina, Zhanna A, Sennikov, Sergey V

“…Tumor necrosis factor (TNF) plays an important role in immune responses to the causative agent of tuberculosis, . Additionally, TNF can also mediate many…”
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TNFR1 Absence Is Not Crucial for Different Types of Cell Reaction to TNF: A Study of the TNFR1-Knockout Cell Model by Alshevskaya, Alina A, Lopatnikova, Julia A, Zhukova, Julia V, Perik-Zavodskaia, Olga Y, Alrhmoun, Saleh, Obleukhova, Irina A, Matveeva, Anna K, Savenkova, Darya A, Imatdinov, Ilnaz R, Yudkin, Dmitry V, Sennikov, Sergey V

“…One of the mechanisms regulating the biological activity of tumor necrosis factor (TNF) in cells is the co-expression of TNFR1/TNFR2 receptors. A model with a…”
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The Effects of Immunosuppressive Factors on Primary Dendritic Cells from C57BL/6 and CBA Mice by Obleukhova, Irina A., Anatolievna, Lopatnikova Julia, Tereschenko, Valeriy P., Khantakova, Julia N., Kurilin, Vasiliy V., Sennikov, Sergey V.

“…Introduction. Dendritic cells (DCs) control immune responses by modulating T and B cells towards effector or tolerogenic responses. In this study, we evaluated…”
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Dendritic Cells Transfected with MHC Antigenic Determinants of CBA Mice Induce Antigen-Specific Tolerance in C57Bl/6 Mice by Bulygin, Aleksey S., Khantakova, Julia N., Knauer, Nadezda Y., Maksyutov, Amir Z., Silkov, Alexander N., Lopatnikova, Julia A., Shevchenko, Julia A., Kurilin, Vasiliy V., Tereshchenko, Valeriy P., Sennikov, Sergey V., Kuznetsova, Maria S.

“…Background. Nonspecific immunosuppressive therapy for graft rejection and graft-versus-host disease (GVHD) is often accompanied by severe side effects such as…”
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In Vitro Model of Suppression of the Alloantigen Response by Tolerogenic Dendritic Cells Transfected with Personalized DNA Constructs Encoding HLA Epitopes by Shevchenko, Julia A., Lopatnikova, Julia A., Khantakova, Julia N., Silkov, Alexander N., Kuznetsova, Maria S., Kurilin, Vasiliy V., Maksyutov, Amir Z., Sennikov, Sergey V.

“…BACKGROUNDA search for efficient graft rejection modulation techniques for the promotion of durable engraftment remains to be a matter of close study all over…”
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Differences of IL-1β Receptors Expression by Immunocompetent Cells Subsets in Rheumatoid Arthritis by Sennikov, Sergey V., Karaulov, Aleksander V., Sizikov, Aleksey E., Chumasova, Oksana A., Shkaruba, Nadezhda S., Anatolievna, Lopatnikova Julia, Alshevskaya, Alina A., Kozlov, Vladimir A.

“…IL-1β is involved in the induction and maintenance of chronic inflammation in rheumatoid arthritis (RA). Its activity is regulated and induced by soluble and…”
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Polymorphisms in the Tumor Necrosis Factor Receptor Genes Affect the Expression Levels of Membrane-Bound Type I and Type II Receptors by Vitalievich, Sennikov Sergei, Anatolievna, Lopatnikova Julia, Vasilyev, Filipp F., Sennikov, Sergey V., Silkov, Alexander N.

“…The level of TNF receptors on various cells of immune system and its association with the gene polymorphism were investigated. Determining the levels of…”
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Autologous dendritic cells and activated cytotoxic T‑cells as combination therapy for breast cancer by Shevchenko, Julia A, Khristin, Alexander A, Kurilin, Vasily V, Kuznetsova, Maria S, Blinova, Darya D, Starostina, Natalya M, Sidorov, Sergey V, Sennikov, Sergey V

“…Breast cancer is the most common oncological pathology in women worldwide. Techniques for improving the clinical parameters of patients undergoing combination…”
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Production of pure fractions of immunoglobulin G subclass autoantibodies against tumor necrosis factor by Kireev, Fedor D., Lopatnikova, Julia A., Sennikov, Sergey V.

“…•A protocol for affinity purification of IgG subclass autoantibodies to TNF is proposed.•Separation of IgG subclasses was performed using both positive and…”
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Transfection of bone marrow derived cells with immunoregulatory proteins by Khantakova, Julia N., Silkov, Alexander N., Tereshchenko, Valeriy P., Gavrilova, Elena V., Maksyutov, Rinat A., Sennikov, Sergey V.

“…•Mφ and DCs are transfected by pDNA more efficiently than bone marrow cells.•Cultured DCs and Mφ reduces the transfection efficiency due to cell…”
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Expression density of receptors to IL-1β in atopic dermatitis by Alshevskaya, Alina A., Lopatnikova, Julia A., Krugleeva, Olga L., Nepomnyschih, Vera M., Lukinov, Vitaliy L., Karaulov, Aleksander V., Sennikov, Sergey V.

“…•Density of cytokine receptors expression needs to be studied in pathology.•Changes in percentage of cells and number of receptors may be differently…”
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The influence of conditioned medium from mouse intestinal epithelial cells on the proliferative activity of crypt cells: role of granulocyte-macrophage colony-stimulating factor by Sennikov, Sergey V, Temchura, Vladimir V, Kozlov, Vladimir A, Trufakin, Valeriy A

“…The aim of this work was to study the influence of soluble factors produced by native mouse intestinal epithelial cells (IECs) on the proliferative activity of…”
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