Search Results - "Serger, Elisabeth"
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The gut metabolite indole-3 propionate promotes nerve regeneration and repair
Published in Nature (London) (21-07-2022)“…The regenerative potential of mammalian peripheral nervous system neurons after injury is critically limited by their slow axonal regenerative rate 1 …”
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Chd7 is indispensable for mammalian brain development through activation of a neuronal differentiation programme
Published in Nature communications (20-03-2017)“…Mutations in chromatin modifier genes are frequently associated with neurodevelopmental diseases. We herein demonstrate that the chromodomain helicase…”
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HIV alters neuronal mitochondrial fission/fusion in the brain during HIV-associated neurocognitive disorders
Published in Neurobiology of disease (01-02-2016)“…Abstract HIV-associated neurocognitive disorders (HAND) still occur in approximately 50% of HIV patients, and therapies to combat HAND progression are urgently…”
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CBP/p300 activation promotes axon growth, sprouting, and synaptic plasticity in chronic experimental spinal cord injury with severe disability
Published in PLoS biology (20-09-2022)“…The interruption of spinal circuitry following spinal cord injury (SCI) disrupts neural activity and is followed by a failure to mount an effective…”
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AMPK controls the axonal regenerative ability of dorsal root ganglia sensory neurons after spinal cord injury
Published in Nature metabolism (01-09-2020)“…Regeneration after injury occurs in axons that lie in the peripheral nervous system but fails in the central nervous system, thereby limiting functional…”
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HIV-1 Tat alters neuronal autophagy by modulating autophagosome fusion to the lysosome: implications for HIV-associated neurocognitive disorders
Published in The Journal of neuroscience (04-02-2015)“…Antiretroviral therapy has increased the life span of HIV+ individuals; however, HIV-associated neurocognitive disorder (HAND) occurrence is increasing in…”
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Epigenomic signatures underpin the axonal regenerative ability of dorsal root ganglia sensory neurons
Published in Nature neuroscience (01-11-2019)“…Axonal injury results in regenerative success or failure, depending on whether the axon lies in the peripheral or the CNS, respectively. The present study…”
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CBP/p300 activation promotes axon growth, sprouting, and synaptic plasticity in chronic experimental spinal cord injury with severe disability
Published in PLoS biology (01-09-2022)“…The interruption of spinal circuitry following spinal cord injury (SCI) disrupts neural activity and is followed by a failure to mount an effective…”
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The circadian clock time tunes axonal regeneration
Published in Cell metabolism (05-12-2023)“…Nerve injuries cause permanent neurological disability due to limited axonal regeneration. Injury-dependent and -independent mechanisms have provided important…”
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