Search Results - "Sergent, Thérèse"
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Phenolic compounds and plant extracts as potential natural anti-obesity substances
Published in Food chemistry (01-11-2012)“…► Polyphenols and plant extracts inhibited the pancreatic lipase in an enzymatic assay. ► EGCG, quercetin and kaempferol were more potent than the antiobesity…”
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Deoxynivalenol affects in vitro intestinal epithelial cell barrier integrity through inhibition of protein synthesis
Published in Toxicology and applied pharmacology (15-06-2010)“…Deoxynivalenol (DON), one of the most common mycotoxin contaminants of raw and processed cereal food, adversely affects the gastrointestinal tract. Since DON…”
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Anti-inflammatory effect and modulation of cytochrome P450 activities by Artemisia annua tea infusions in human intestinal Caco-2 cells
Published in Food chemistry (15-09-2012)“…► Characterisation and effect of Artemisia annua extracts on intestinal function. ► Rosmarinic and chlorogenic acids identified as the main phenolic compounds…”
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Food flavonoid aryl hydrocarbon receptor-mediated agonistic/antagonistic/synergic activities in human and rat reporter gene assays
Published in Analytica chimica acta (01-04-2009)“…Aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor mediating the adverse effects of dioxins and polycyclic aromatic hydrocarbons…”
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CYP1A1 and CYP3A4 modulation by dietary flavonoids in human intestinal Caco-2 cells
Published in Toxicology letters (15-12-2009)“…Flavonoids have been proposed to exert beneficial effects in a multitude of disease states. However, evidence of potential toxic actions has also emerged…”
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Anti-inflammatory effects of dietary phenolic compounds in an in vitro model of inflamed human intestinal epithelium
Published in Chemico-biological interactions (05-12-2010)“…Phenolic compounds (PCs) are considered to possess anti-inflammatory properties and therefore were proposed as an alternative natural approach to prevent or…”
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Deoxynivalenol transport across human intestinal Caco-2 cells and its effects on cellular metabolism at realistic intestinal concentrations
Published in Toxicology letters (01-07-2006)“…Deoxynivalenol (DON) is a mycotoxin of the trichothecenes family to which human exposure levels can be high. Epidemiological studies suggest a link between DON…”
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In vitro investigation of intestinal transport mechanism of silicon, supplied as orthosilicic acid‐vanillin complex
Published in Molecular nutrition & food research (01-02-2017)“…Scope Silicon (Si) is one of the most abundant trace elements in the body. Although pharmacokinetics data described its absorption from the diet and its body…”
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Characterization of black locust (Robinia pseudoacacia L.) heartwood extractives: identification of resveratrol and piceatannol
Published in Wood science and technology (2014)“…Robinia pseudoacacia L. heartwood is characterized by a very high natural durability. However, a significant difference was observed between the mature and…”
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Molecular and cellular effects of food contaminants and secondary plant components and their plausible interactions at the intestinal level
Published in Food and chemical toxicology (01-03-2008)“…The intestinal mucosa is not simply a barrier allowing entry of compounds such as nutrients or chemicals, and restricting that of others. Intestinal cells and…”
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CYP1A1 induction and CYP3A4 inhibition by the fungicide imazalil in the human intestinal Caco-2 cells—Comparison with other conazole pesticides
Published in Toxicology letters (10-02-2009)“…Imazalil (IMA) is a widely used imidazole-antifungal pesticide and, therefore, a food contaminant. This compound is also used as a drug (enilconazole). As…”
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Chemistry around imidazopyrazine and ibuprofen: Discovery of novel fatty acid amide hydrolase (FAAH) inhibitors
Published in European journal of medicinal chemistry (01-09-2010)“…Based on the imidazo-[1,2-a]-pyrazin-3-(7H)-one scaffold, a dual action prodrug has been designed for combining antioxidant and anti-inflammatory activities,…”
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Differential modulation of ochratoxin A absorption across Caco-2 cells by dietary polyphenols, used at realistic intestinal concentrations
Published in Toxicology letters (15-10-2005)“…The effect of polyphenols (PPs) on the absorption of ochratoxin A (OTA), a food-borne mycotoxin, was investigated in an in vitro model of the human intestinal…”
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Interaction of ochratoxin A with human intestinal Caco-2 cells: possible implication of a multidrug resistance-associated protein (MRP2)
Published in Toxicology letters (11-04-2003)“…Ochratoxin A (OTA), a nephrotoxic mycotoxin, is absorbed from small intestine and, in plasma, binds to serum albumin. Prolonged half-live results from…”
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Development of a triculture based system for improved benefit/risk assessment in pharmacology and human food
Published in BMC proceedings (22-11-2011)“…Cell monolayer integrity, both in mono-, co- and tri-cultures, was controlled by measurement of the transepithelial electrical resistance (TEER, Millipore…”
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Smooth muscle cells influence monocyte response to LDL as well as their adhesion and transmigration in a coculture model of the arterial wall
Published in Journal of vascular research (01-09-2001)“…We investigated the possible interference of smooth muscle cells with monocyte response to LDL as well as with their adhesion and transmigration in a coculture…”
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Imazalil modulates CYPs 1A1 and 3A4 activities in the human Caco-2 cells as an intestinal model to assess food safety
Published in Toxicology letters (2007)Get full text
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Imazalil is an aryl hydrocarbon receptor (AhR) antagonist in AhR-dependent reporter human and rat hepatoma cells
Published in Toxicology letters (2007)Get full text
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Study of the flavonoids effect on the AhR-dependent transcription using reporter gene assays
Published in Journal of biotechnology (01-09-2007)Get full text
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