Search Results - "Seredenin, SB"
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Mimetics of brain-derived neurotrophic factor loops 1 and 4 are active in a model of ischemic stroke in rats
Published in Drug design, development and therapy (01-01-2016)“…Two dimeric dipeptides, -(N-monosuccinyl-l-seryl-l-lysine)hexamethylenediamide (GSB-106) and -(N-monosuccinyl-l-methionyl-l-serine) heptamethylenediamide…”
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2
Synthesis and antiamnesic activity of a series of N-acylprolyl-containing dipeptides
Published in European journal of medicinal chemistry (1996)“…Esters and amides of a series of N-acylprolyl-containing dipeptides were synthesized. It was established that these substances possess the ability to prevent…”
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3
GVS‐111 prevents oxidative damage and apoptosis in normal and Down's syndrome human cortical neurons
Published in International journal of developmental neuroscience (01-05-2003)“…The neuroprotective activity of a novel N‐acylprolyl‐containing dipeptide analog of the nootropic 2‐oxo‐1‐pyrrolidine acetamide (Piracetam) designated as…”
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4
Neuroprotective properties of afobazol in vitro
Published in Bulletin of experimental biology and medicine (01-08-2005)“…The effects of a novel selective anxiolytic afobazol on survival of HT-22 neurons were studied in the model of oxidative stress and glutamate toxicity. In both…”
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5
Neuroprotective effects of afobazol in experimental cerebral hemorrhage
Published in Bulletin of experimental biology and medicine (01-11-2005)“…The study of novel selective anxiolytic afobazol on rats with experimental intracerebral post-traumatic hematoma (cerebral hemorrhage) demonstrated its…”
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6
Behavioral Similarities and Differences among Alcohol-Preferring and -Nonpreferring Rats: Confirmation by Factor Analysis and Extension to Additional Groups
Published in Alcoholism, clinical and experimental research (01-08-1997)“…Thirteen behavioral variables from six tasks were measured in alcohol‐preferring (AA, FH, and P) and ‐non‐preferring (ANA, FRL, and NP) rat lines/strains and…”
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7
Identification of a novel endogenous memory facilitating cyclic dipeptide cyclo-prolylglycine in rat brain
Published in FEBS letters (05-08-1996)“…Using high-performance liquid chromatography, gas-chromatography and chromato-mass spectrometry methods a novel endogenous cyclic dipeptide cyclo-prolylglycine…”
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8
Co-mutagenesis as new vistas in genotoxicology
Published in Bulletin of experimental biology and medicine (01-06-2003)Get full text
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9
To drink or not to drink: Tests of anxiety and immobility in alcohol-preferring and alcohol-nonpreferring rat strains
Published in Physiology & behavior (01-05-1995)“…Previous reports have provided mixed results about emotional states in rats that voluntarily drink substantial amounts of alcohol. The purpose of the present…”
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10
Pharmacogenetic study of anxiolytic effects of new cholecystokinin receptor antagonists in animals with different levels of emotionality
Published in Bulletin of experimental biology and medicine (01-05-2003)“…Effects of two new peptide antagonists of central cholecystokinin receptors, GB-101 (0.05-0.40 mg/kg) and GB-115 (0.006-0.100 mg/kg), on the behavior of inbred…”
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11
Design of N-Acylprolyltyrosine “Tripeptoid” Analogues of Neurotensin as Potential Atypical Antipsychotic Agents
Published in Journal of medicinal chemistry (29-01-1998)“…A series of N-acylprolyltyrosine amides was designed as tripeptoid analogues of neurotensin. The substituted dipeptides were tested in vivo for antidopamine…”
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12
Verapamil contributes to the clastogenic effects of acrylamide, cyclophosphamide, and dioxidine on somatic cells of BALB/C and C57BL/6 mice
Published in Mutation research (06-04-1999)“…The chromosome aberration assay of metaphase bone marrow cells was used to study the clastogenic effects of acrylamide, cyclophosphamide, dioxidine, and their…”
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13
Memory restoring and neuroprotective effects of the proline-containing dipeptide, GVS-111, in a photochemical stroke model
Published in Behavioural pharmacology (01-09-1999)“…Local thrombosis of the frontal cortex (Fr1 and Fr3 fields), caused by combination of the intravenous photosensitive dye Rose Bengal administration with…”
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14
Analysis of BDNF in brain structures of inbred mice with different phenotypes of mental and stress reaction
Published in Bulletin of experimental biology and medicine (01-11-2005)“…The content of BDNF was measured in cerebral structures of intact C57Bl/6 and BALB/c mice in winter and spring. The level of cerebral neurotrophic factor in…”
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15
Comparative analysis of EEG spatial organization in the rats with different level of genetically determinated anxiety under ethanol
Published in Zurnal vyss̆ej nervnoj dejatelnosti imeni I P Pavlova (01-11-2004)“…The pecularities of EEG changes in the rats with geneticaly different level of anxiety was studed after ethanol injection. The biopotentials spatial…”
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16
cDNA macroarray analysis of gene expression changes in rat brain after a single administration of a 2-aminoadamantane derivative
Published in Molecular biology (New York) (01-03-2005)“…The Atlas(TM) Rat cDNA Expression Array (BD Biosciences, United States) has been used to analyze changes in the expression of 588 genes in rat brain cells in…”
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17
Anxiolytic activity of endogenous nootropic dipeptide cycloprolylglycine in elevated plus-maze test
Published in Bulletin of experimental biology and medicine (01-05-2001)“…Testing in an elevated plus-maze revealed dose-dependent anxiolytic activity of piracetam analog cycloprolylglycine. Intraperitoneal injection of this agent…”
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18
Designing nootropic dipeptides using an evolutionary-genetic approach
Published in Pharmaceutical chemistry journal (01-01-2006)“…A novel approach to the search for the new groups of biologically active peptides is developed, which is based on the selection of point mutants with respect…”
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19
Pain sensitivity and saccharin intake in alcohol-preferring and -nonpreferring rat strains
Published in Physiology & behavior (01-04-1996)“…The experiments were designed to study the association between consumption of palatable 0.1% (w/v) saccharin solution, voluntary drinking of 10% (v/v) ethanol…”
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20
Emotionality and spatio-temporal organization of momentary EEG potentials
Published in Zurnal vyss̆ej nervnoj dejatelnosti imeni I P Pavlova (01-07-2005)“…With the aim to reveal features of the neocortical spatiotemporal organization of potentials characteristic of different genetically predetermined emotional…”
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