Search Results - "Seraihi, Ahad Al"

Myelodysplasia and liver disease extend the spectrum of RTEL1 related telomeropathies by Cardoso, Shirleny R, Ellison, Alicia C M, Walne, Amanda J, Cassiman, David, Raghavan, Manoj, Kishore, Bhuvan, Ancliff, Philip, Rodríguez-Vigil, Carmen, Dobbels, Bieke, Rio-Machin, Ana, Al Seraihi, Ahad F H, Pontikos, Nikolas, Tummala, Hemanth, Vulliamy, Tom, Dokal, Inderjeet

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Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma by Okosun, Jessica, Wolfson, Rachel L, Wang, Jun, Araf, Shamzah, Wilkins, Lucy, Castellano, Brian M, Escudero-Ibarz, Leire, Al Seraihi, Ahad Fahad, Richter, Julia, Bernhart, Stephan H, Efeyan, Alejo, Iqbal, Sameena, Matthews, Janet, Clear, Andrew, Guerra-Assunção, José Afonso, Bödör, Csaba, Quentmeier, Hilmar, Mansbridge, Christopher, Johnson, Peter, Davies, Andrew, Strefford, Jonathan C, Packham, Graham, Barrans, Sharon, Jack, Andrew, Du, Ming-Qing, Calaminici, Maria, Lister, T Andrew, Auer, Rebecca, Montoto, Silvia, Gribben, John G, Siebert, Reiner, Chelala, Claude, Zoncu, Roberto, Sabatini, David M, Fitzgibbon, Jude

“…Jessica Okosun, David Sabatini and colleagues identify recurrent RRAGC mutations in follicular lymphoma, resulting in activated mTORC1 signaling. The…”
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KDM5 inhibition offers a novel therapeutic strategy for the treatment of KMT2D mutant lymphomas by Heward, James, Koniali, Lola, D'Avola, Annalisa, Close, Karina, Yeomans, Alison, Philpott, Martin, Dunford, James, Rahim, Tahrima, Al Seraihi, Ahad F., Wang, Jun, Korfi, Koorosh, Araf, Shamzah, Iqbal, Sameena, Bewicke-Copley, Findlay, Kumar, Emil, Barisic, Darko, Calaminici, Maria, Clear, Andrew, Gribben, John, Johnson, Peter, Neve, Richard, Cutillas, Pedro, Okosun, Jessica, Oppermann, Udo, Melnick, Ari, Packham, Graham, Fitzgibbon, Jude

“…Loss-of-function mutations in KMT2D are a striking feature of germinal center (GC) lymphomas, resulting in decreased histone 3 lysine 4 (H3K4) methylation and…”
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The complex genetic landscape of familial MDS and AML reveals pathogenic germline variants by Rio-Machin, Ana, Vulliamy, Tom, Hug, Nele, Walne, Amanda, Tawana, Kiran, Cardoso, Shirleny, Ellison, Alicia, Pontikos, Nikolas, Wang, Jun, Tummala, Hemanth, Al Seraihi, Ahad Fahad H., Alnajar, Jenna, Bewicke-Copley, Findlay, Armes, Hannah, Barnett, Michael, Bloor, Adrian, Bödör, Csaba, Bowen, David, Fenaux, Pierre, Green, Andrew, Hallahan, Andrew, Hjorth-Hansen, Henrik, Hossain, Upal, Killick, Sally, Lawson, Sarah, Layton, Mark, Male, Alison M., Marsh, Judith, Mehta, Priyanka, Mous, Rogier, Nomdedéu, Josep F., Owen, Carolyn, Pavlu, Jiri, Payne, Elspeth M., Protheroe, Rachel E., Preudhomme, Claude, Pujol-Moix, Nuria, Renneville, Aline, Russell, Nigel, Saggar, Anand, Sciuccati, Gabriela, Taussig, David, Toze, Cynthia L., Uyttebroeck, Anne, Vandenberghe, Peter, Schlegelberger, Brigitte, Ripperger, Tim, Steinemann, Doris, Wu, John, Mason, Joanne, Page, Paula, Akiki, Susanna, Reay, Kim, Cavenagh, Jamie D., Plagnol, Vincent, Caceres, Javier F., Fitzgibbon, Jude, Dokal, Inderjeet

“…The inclusion of familial myeloid malignancies as a separate disease entity in the revised WHO classification has renewed efforts to improve the recognition…”
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GATA2 monoallelic expression underlies reduced penetrance in inherited GATA2-mutated MDS/AML by Al Seraihi, Ahad F., Rio-Machin, Ana, Tawana, Kiran, Bödör, Csaba, Wang, Jun, Nagano, Ai, Heward, James A., Iqbal, Sameena, Best, Steven, Lea, Nicholas, McLornan, Donal, Kozyra, Emilia J., Wlodarski, Marcin W., Niemeyer, Charlotte M., Scott, Hamish, Hahn, Chris, Ellison, Alicia, Tummala, Hemanth, Cardoso, Shirleny Romualdo, Vulliamy, Tom, Dokal, Inderjeet, Butler, Tom, Smith, Matthew, Cavenagh, Jamie, Fitzgibbon, Jude

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Genome instability is a consequence of transcription deficiency in patients with bone marrow failure harboring biallelic ERCC6L2 variants by Tummala, Hemanth, Dokal, Arran D., Walne, Amanda, Ellison, Alicia, Cardoso, Shirleny, Amirthasigamanipillai, Saranha, Kirwan, Michael, Browne, Isobel, Sidhu, Jasmin K., Rajeeve, Vinothini, Rio-Machin, Ana, Seraihi, Ahad Al, Duncombe, Andrew S., Jenner, Matthew, Smith, Owen P., Enright, Helen, Norton, Alice, Aksu, Tekin, Özbek, Namık Yaşar, Pontikos, Nikolas, Cutillas, Pedro, Dokal, Inderjeet, Vulliamy, Tom

“…Biallelic variants in the ERCC excision repair 6 like 2 gene (ERCC6L2) are known to cause bone marrow failure (BMF) due to defects in DNA repair and…”
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SARS-CoV-2 Reinfection Rate and Outcomes in Saudi Arabia: A National Retrospective Study by Al-Otaiby, Maram, Krissaane, Ines, Al Seraihi, Ahad, Alshenaifi, Jumanah, Qahtani, Mohammad Hassan, Aljeri, Thamer, Zaatari, Ezzedine, Hassanain, Mazen, Algwizani, Abdullah, Albarrag, Ahmed, Al-Mozaini, Maha, Alabdulaali, Mohammed

“…•SARS-CoV-2 reinfection was estimated at 0.8% over a 20-month follow-up in Saudi Arabia.•Diabetes, HIV, obesity, and working in health care were associated…”
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Familial emberger syndrome with autoimmunity, hyper-immunoglobulin E and lymphatic impairment caused by a novel GATA2 mutation by AlGassim, Moneerah, Al Seraihi, Ahad F., AlShaibani, AlFadel, Conca, Walter, AlShehri, Saleem, Moustafa Abouzied, Moheieldin, Hamadah, Issam, AlReshoodi, Saleh, Dasouki, Majed, Sheikh, Farrukh

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Demographic Characteristics, Comorbidities, and Length of Stay of COVID-19 Patients Admitted Into Intensive Care Units in Saudi Arabia: A Nationwide Retrospective Study by Al-Otaiby, Maram, Almutairi, Khalid M., Vinluan, Jason M., Al Seraihi, Ahad, Alonazi, Wadi B., Qahtani, Mohammad Hassan, Aljeri, Thamer, Alhumud, Manal A., Alobaidi, Nadhar, Alhurishi, Sultana A.

“…Background This study aimed to describe the demographic characteristics and determine the risk factors associated with disease severity and length of hospital…”
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Pattern of self-reported adverse events related to COVID-19 vaccines in Saudi Arabia: A nationwide study by Alkhalifah, Joud Mohammed, Al Seraihi, Ahad, Al-Tawfiq, Jaffar A, Alshehri, Badr Fadhel, Alhaluli, Alhanouf Hani, Alsulais, Naif Mansour, Alessa, Mohammed Mesfer, Seddiq, Waleed, Aljeri, Thamer, Qahtani, Mohammad Hassan, Barry, Mazin, Al-Otaiby, Maram

“…Vaccination against coronavirus disease 2019 (COVID-19) is the most effective way to end the pandemic. Any development of adverse events (AEs) from various…”
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Recurrent somatic JAK-STAT pathway variants within a RUNX1-mutated pedigree by Tawana, Kiran, Wang, Jun, Király, Péter A, Kállay, Krisztián, Benyó, Gábor, Zombori, Marianna, Csomor, Judit, Al Seraihi, Ahad, Rio-Machin, Ana, Matolcsy, András, Chelala, Claude, Cavenagh, Jamie, Fitzgibbon, Jude, Bödör, Csaba

“…Germline variants within the transcription factor RUNX1 are associated with familial platelet disorder and acute leukemia in over 40% of carriers. At present,…”
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Variable Penetrance Is Linked with Monoallelic Gene Expression in Inherited GATA2-Mutated MDS/AML by Al Seraihi, Ahad, Rio-Machin, Ana, Tawana, Kiran, Bödör, Csaba, Araf, Shamzah, Heward, James A, Smith, Matthew, Iqbal, Sameena, Best, Steven, Lea, Nicholas, McLornan, Donal, Ellison, Alicia, Tummala, Hemanth, Romualdo Cardoso, Shirleny, Cavenagh, Jamie D., Vulliamy, Tom, Dokal, Inderjeet, Fitzgibbon, Jude

“…Background: While myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) are considered sporadic hematopoietic stem cell clonal disorders, there are…”
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Erratum: Corrigendum: Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma by Okosun, Jessica, Wolfson, Rachel L, Wang, Jun, Araf, Shamzah, Wilkins, Lucy, Castellano, Brian M, Escudero-Ibarz, Leire, Seraihi, Ahad Fahad Al, Richter, Julia, Bernhart, Stephan H, Efeyan, Alejo, Iqbal, Sameena, Matthews, Janet, Clear, Andrew, Guerra-Assunção, José Afonso, Bödör, Csaba, Quentmeier, Hilmar, Mansbridge, Christopher, Johnson, Peter, Davies, Andrew, Strefford, Jonathan C, Packham, Graham, Barrans, Sharon, Jack, Andrew, Du, Ming-Qing, Calaminici, Maria, Lister, T Andrew, Auer, Rebecca, Montoto, Silvia, Gribben, John G, Siebert, Reiner, Chelala, Claude, Zoncu, Roberto, Sabatini, David M, Fitzgibbon, Jude

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Familial Emberger Syndrome With Autoimmunity, Hyper-Immunoglobulin E and Lymphatic Impairment Caused by a Novel GATA2 Mutation by AlGassim, Moneerah, Al Seraihi, Ahad F, AlShaibani, AlFadel, Conca, Walter, AlShehri, Saleem, Abouzied, Moheieldin Moustafa, Hamadah, Issam, AlReshoodi, Saleh, Dasouki, Majed, Sheikh, Farrukh

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Correction: Corrigendum: Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma by Okosun, Jessica, Wolfson, Rachel L, Wang, Jun, Araf, Shamzah, Wilkins, Lucy, Castellano, Brian M, Escudero-Ibarz, Leire, Seraihi, Ahad Fahad Al, Richter, Julia, Bernhart, Stephan H, Efeyan, Alejo, Iqbal, Sameena, Matthews, Janet, Clear, Andrew, Guerra-Assunção, José Afonso, Bödör, Csaba, Quentmeier, Hilmar, Mansbridge, Christopher, Johnson, Peter, Davies, Andrew, Strefford, Jonathan C, Packham, Graham, Barrans, Sharon, Jack, Andrew, Du, Ming-Qing, Calaminici, Maria, Lister, T Andrew, Auer, Rebecca, Montoto, Silvia, Gribben, John G, Siebert, Reiner, Chelala, Claude, Zoncu, Roberto, Sabatini, David M, Fitzgibbon, Jude

“…Nat. Genet.; 10.1038/ng.3473; corrected online 12 January 2016 In the version of this article initially published online, several funding sources were omitted…”
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Corrigendum: Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma by Okosun, Jessica, Wolfson, Rachel L, Wang, Jun, Araf, Shamzah, Wilkins, Lucy, Castellano, Brian M, Escudero-Ibarz, Leire, Seraihi, Ahad Fahad Al, Richter, Julia, Bernhart, Stephan H, Efeyan, Alejo, Iqbal, Sameena, Matthews, Janet, Clear, Andrew, Guerra-Assunção, José Afonso, Bödör, Csaba, Quentmeier, Hilmar, Mansbridge, Christopher, Johnson, Peter, Davies, Andrew, Strefford, Jonathan C, Packham, Graham, Barrans, Sharon, Jack, Andrew, Du, Ming-Qing, Calaminici, Maria, Lister, T Andrew, Auer, Rebecca, Montoto, Silvia, Gribben, John G, Siebert, Reiner, Chelala, Claude, Zoncu, Roberto, Sabatini, David M, Fitzgibbon, Jude

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Corrigendum: Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma by Okosun, Jessica, Wolfson, Rachel L, Wang, Jun, Araf, Shamzah, Wilkins, Lucy, Castellano, Brian M, Escudero-Ibarz, Leire, Seraihi, Ahad Fahad Al, Richter, Julia, Bernhart, Stephan H, Efeyan, Alejo, Iqbal, Sameena, Matthews, Janet, Clear, Andrew, Guerra-Assunção, José Afonso, Bödör, Csaba, Quentmeier, Hilmar, Mansbridge, Christopher, Johnson, Peter, Davies, Andrew, Strefford, Jonathan C, Packham, Graham, Barrans, Sharon, Jack, Andrew, Du, Ming-Qing, Calaminici, Maria, Lister, T Andrew, Auer, Rebecca, Montoto, Silvia, Gribben, John G, Siebert, Reiner, Chelala, Claude, Zoncu, Roberto, Sabatini, David M, Fitzgibbon, Jude

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