Search Results - "Serafini, Francesca"
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Natural products from aquatic eukaryotic microorganisms for cancer therapy: Perspectives on anti-tumour properties of ciliate bioactive molecules
Published in Pharmacological research (01-11-2016)“…[Display omitted] Several modern drugs, including those for cancer therapy, have been isolated from natural sources, are based on natural products and its…”
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Dysfunctional autophagy induced by the pro-apoptotic natural compound climacostol in tumour cells
Published in Cell death & disease (19-12-2018)“…Autophagy occurs at a basal level in all eukaryotic cells and may support cell survival or activate death pathways. Due to its pathophysiologic significance,…”
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Climacostol reduces tumour progression in a mouse model of melanoma via the p53-dependent intrinsic apoptotic programme
Published in Scientific reports (07-06-2016)“…Climacostol, a compound produced by the ciliated protozoan Climacostomum virens , displayed cytotoxic properties in vitro . This study demonstrates that it has…”
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Bioactivity and Structural Properties of Novel Synthetic Analogues of the Protozoan Toxin Climacostol
Published in Toxins (15-01-2019)“…Climacostol (5-[(2 )-non-2-en-1-yl]benzene-1,3-diol) is a resorcinol produced by the protozoan for defence against predators. It exerts a potent antimicrobial…”
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Sperm quality improvement after natural anti-oxidant treatment of asthenoteratospermic men with leukocytospermia
Published in Asian journal of andrology (01-03-2008)“…Aim: To study the immune-modulating and anti-oxidant effects of beta-glucan, papaya, lactoferrin, and vitamins C and E on sperm characteristics of patients…”
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Intracytoplasmic sperm injection and pregnancy with decapitated sperm
Published in Fertility and sterility (01-03-2010)“…Objective To perform intracytoplasmic sperm injection (ICSI) in couples with primary infertility owing to sperm defects causing total immotility. Design Case…”
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Spermatogenesis in a Man with Complete Deletion of USP9Y
Published in The New England journal of medicine (26-02-2009)“…The azoospermia factor region A ( AZFA ) on chromosome Y contains two genes, one of which is USP9Y . Deletions in this region have been associated with male…”
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Prospective memory performance of patients with Parkinson's disease depends on shifting aptitude: evidence from cognitive rehabilitation
Published in Journal of the International Neuropsychological Society (01-08-2014)“…This study investigated the effect of cognitive training aimed at improving shifting ability on Parkinson's disease (PD) patients' performance of prospective…”
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A pilot study on the effect of cognitive training on BDNF serum levels in individuals with Parkinson's disease
Published in Frontiers in human neuroscience (16-03-2015)“…Parkinson's disease (PD) patients, besides motor dysfunctions, may also display mild cognitive deficits (MCI) which increase with disease progression. The…”
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Prospective Memory Performance in Individuals With Parkinson's Disease Who Have Mild Cognitive Impairment
Published in Neuropsychology (01-09-2015)“…Objective: Prospective memory (PM) is the ability to keep in memory and realize future intentions. We aimed at investigating whether in Parkinson's disease…”
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Sperm quality and pregnancy rate after COX-2 inhibitor therapy of infertile males with abacterial leukocytospermia
Published in Human reproduction (Oxford) (01-04-2007)“…BACKGROUND Leukocytes are a frequent finding in seminal plasma of infertile males with abacterial inflammation. We evaluated the effects of treatment with…”
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Time-based prospective memory functioning in mild cognitive impairment associated with Parkinson's disease: relationship with autonomous management of daily living commitments
Published in Frontiers in human neuroscience (10-06-2015)“…Prospective memory (PM), that is, the ability to keep in memory and carry out intentions in the future, is reported to be impaired in individuals with…”
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Sperm aneuploidies after human recombinant follicle stimulating hormone therapy in infertile males
Published in Reproductive biomedicine online (2009)“…Abstract Errors in sperm chromosome segregation are frequently observed in infertile males. It would therefore be useful to develop methods for reducing the…”
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Fluorescence in situ hybridization and molecular studies in infertile men with dysplasia of the fibrous sheath
Published in Fertility and sterility (01-07-2005)“…To perform fluorescence in situ hybridization (FISH) and molecular analysis in patients with the genetic sperm defect "dysplasia of the fibrous sheath" (DFS)…”
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Spermatogenesis in a Man with Complete Deletion of USP9YBrief Report
Published in The New England journal of medicine (26-02-2009)“…Deletions in the azoospermia factor region AZFa on the human Y chromosome and, more specifically, in the region that encompasses the ubiquitin-specific…”
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A site-specific controlled-release system for metformin
Published in Journal of pharmacy and pharmacology (01-05-2005)“…Oral absorption of the antihyperglycaemic agent metformin hydrochloride (MF‐HCl) is confined to the upper part of the intestine, therefore rational…”
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Methyl-DEAE-dextran: a candidate biomaterial
Published in Bio-medical materials and engineering (2004)“…The full quaternisation of DEAE-dextran was successfully attempted and an application of the quaternised product was suggested. Commercial DEAE-dextran was…”
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Evaluation of a silicone based matrix containing a crosslinked polyethylene glycol as a controlled drug delivery system for potential oral application
Published in Journal of controlled release (1995)“…A silicone based matrix containing dispersed medicated granules of a crosslinked polyethylene glycol with high swelling capacity is evaluated for its potential…”
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