Search Results - "Seppänen‐Kaijansinkko, Riitta"

Mesenchymal Stem Cells and Extracellular Vesicles in Osteosarcoma Pathogenesis and Therapy by Sarhadi, Virinder Kaur, Daddali, Ravindra, Seppänen-Kaijansinkko, Riitta

“…Osteosarcoma (OS) is an aggressive bone tumor that mainly affects children and adolescents. OS has a strong tendency to relapse and metastasize, resulting in…”
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Efficient ultrafiltration-based protocol to deplete extracellular vesicles from fetal bovine serum by Kornilov, Roman, Puhka, Maija, Mannerström, Bettina, Hiidenmaa, Hanna, Peltoniemi, Hilkka, Siljander, Pia, Seppänen-Kaijansinkko, Riitta, Kaur, Sippy

“…Fetal bovine serum (FBS) is the most commonly used supplement in studies involving cell-culture experiments. However, FBS contains large numbers of bovine…”
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Monocyte‐derived extracellular vesicles stimulate cytokine secretion and gene expression of matrix metalloproteinases by mesenchymal stem/stromal cells by Gebraad, Arjen, Kornilov, Roman, Kaur, Sippy, Miettinen, Susanna, Haimi, Suvi, Peltoniemi, Hilkka, Mannerström, Bettina, Seppänen‐Kaijansinkko, Riitta

“…Intercellular communication is essential in bone remodelling to ensure that new bone is formed with only temporary bone loss. Monocytes (MCs) and osteoclasts…”
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Extracellular small non-coding RNA contaminants in fetal bovine serum and serum-free media by Mannerström, Bettina, Paananen, Riku O., Abu-Shahba, Ahmed G., Moilanen, Jukka, Seppänen-Kaijansinkko, Riitta, Kaur, Sippy

“…In the research field of extracellular vesicles (EVs), the use of fetal bovine serum (FBS) depleted of EVs for in vitro studies is advocated to eliminate the…”
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Patient‐Specific Bioimplants and Reconstruction Plates for Mandibular Defects: Production Workflow and In Vivo Large Animal Model Study by Dienel, Kasper, Abu‐Shahba, Ahmed, Kornilov, Roman, Björkstrand, Roy, Bochove, Bas, Snäll, Johanna, Wilkman, Tommy, Mesimäki, Karri, Meller, Anna, Lindén, Jere, Lappalainen, Anu, Partanen, Jouni, Seppänen‐Kaijansinkko, Riitta, Seppälä, Jukka, Mannerström, Bettina

“…A major challenge with extensive craniomaxillofacial bone reconstruction is the limited donor‐site availability to reconstruct defects predictably and…”
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Small non-coding RNA landscape of extracellular vesicles from human stem cells by Kaur, Sippy, Abu-Shahba, Ahmed G., Paananen, Riku O., Hongisto, Heidi, Hiidenmaa, Hanna, Skottman, Heli, Seppänen-Kaijansinkko, Riitta, Mannerström, Bettina

“…Extracellular vesicles (EVs) are reported to be involved in stem cell maintenance, self-renewal, and differentiation. Due to their bioactive cargoes…”
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Epigenetic alterations in mesenchymal stem cells by osteosarcoma-derived extracellular vesicles by Mannerström, Bettina, Kornilov, Roman, Abu-Shahba, Ahmed G., Chowdhury, Iftekhar M., Sinha, Snehadri, Seppänen-Kaijansinkko, Riitta, Kaur, Sippy

“…Extracellular vesicles (EVs) are central to intercellular communication and play an important role in cancer progression and development. Osteosarcoma (OS) is…”
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Adipose-Derived Mesenchymal Stem Cells do not Affect the Invasion and Migration Potential of Oral Squamous Carcinoma Cells by Sinha, Snehadri, Narjus-Sterba, Matilda, Tuomainen, Katja, Kaur, Sippy, Seppänen-Kaijansinkko, Riitta, Salo, Tuula, Mannerström, Bettina, Al-Samadi, Ahmed

“…Mesenchymal stem cells (MSCs) are commonly isolated from bone marrow and adipose tissue. Depending on the tissue of origin, MSCs have different characteristics…”
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Effects of vatinoxan on xylazine‐induced pulmonary alterations in sheep by Adam, Magdy, Lindén, Jere, Raekallio, Marja, Meller, Anna, Mannerström, Bettina, Abu‐Shahba, Ahmed, Seppänen‐Kaijansinkko, Riitta, Salla, Kati

“…It was hypothesized that premedication with vatinoxan, a peripheral α2‐adrenoceptor antagonist, would mitigate xylazine‐induced pulmonary alterations in sheep…”
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Cranioplasty with Adipose‐Derived Stem Cells, Beta‐Tricalcium Phosphate Granules and Supporting Mesh: Six‐Year Clinical Follow‐Up Results by Thesleff, Tuomo, Lehtimäki, Kai, Niskakangas, Tero, Huovinen, Sanna, Mannerström, Bettina, Miettinen, Susanna, Seppänen‐Kaijansinkko, Riitta, Öhman, Juha

“…Several alternative techniques exist to reconstruct skull defects. The complication rate of the cranioplasty procedure is high and the search for optimal…”
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Electrically Stimulated Adipose Stem Cells on Polypyrrole-Coated Scaffolds for Smooth Muscle Tissue Engineering by Björninen, Miina, Gilmore, Kerry, Pelto, Jani, Seppänen-Kaijansinkko, Riitta, Kellomäki, Minna, Miettinen, Susanna, Wallace, Gordon, Grijpma, Dirk, Haimi, Suvi

“…We investigated the use of polypyrrole (PPy)-coated polymer scaffolds and electrical stimulation (ES) to differentiate adipose stem cells (ASCs) towards smooth…”
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MicroRNA Methylation in Colorectal Cancer by Kaur, Sippy, Lotsari-Salomaa, Johanna E, Seppänen-Kaijansinkko, Riitta, Peltomäki, Päivi

“…Epigenetic alterations such as DNA methylation, histone modifications and non-coding RNA (including microRNA) associated gene silencing have been identified as…”
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Human Adipose Stem Cells Differentiated on Braided Polylactide Scaffolds Is a Potential Approach for Tendon Tissue Engineering by Vuornos, Kaisa, Björninen, Miina, Talvitie, Elina, Paakinaho, Kaarlo, Kellomäki, Minna, Huhtala, Heini, Miettinen, Susanna, Seppänen-Kaijansinkko, Riitta, Haimi, Suvi

“…Growing number of musculoskeletal defects increases the demand for engineered tendon. Our aim was to find an efficient strategy to produce tendon-like matrix…”
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Concentrations of vatinoxan and xylazine in plasma, cerebrospinal fluid and brain tissue following intravenous administration in sheep by Adam, Magdy, Lindén, Jere, Raekallio, Marja, Abu-Shahba, Ahmed, Mannerström, Bettina, Seppänen-Kaijansinkko, Riitta, Meller, Anna, Salla, Kati

“…To investigate the extent of vatinoxan distribution into sheep brain, and whether vatinoxan influences brain concentrations of xylazine; and to examine the…”
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Publisher Correction: Extracellular small non-coding RNA contaminants in fetal bovine serum and serum-free media by Mannerström, Bettina, Paananen, Riku O., Abu-Shahba, Ahmed G., Moilanen, Jukka, Seppänen-Kaijansinkko, Riitta, Kaur, Sippy

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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High percentage of oral lichen planus and lichenoid lesion in oral squamous cell carcinomas by Ruokonen, Hellevi M A, Juurikivi, Aino, Kauppila, Timo, Heikkinen, Anna Maria, Seppänen-Kaijansinkko, Riitta

“…Oral lichen planus (OLP) and lichenoid lesions (OLL) are regarded as precursor lesions of oral squamous cell carcinoma (OSCC) with potential for malignant…”
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Proangiogenic Hypoxia-Mimicking Agents Attenuate Osteogenic Potential of Adipose Stem/Stromal Cells by Abu-Shahba, Ahmed G, Gebraad, Arjen, Kaur, Sippy, Paananen, Riku O, Peltoniemi, Hilkka, Seppänen-Kaijansinkko, Riitta, Mannerström, Bettina

“…Insufficient vascularization hampers bone tissue engineering strategies for reconstructing large bone defects. Delivery of prolyl-hydroxylase inhibitors (PHIs)…”
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Surgical Therapies and Tissue Engineering: At the Intersection Between Innovation and Regulation by Rubin, J Peter, Gurtner, Geoffrey C, Liu, Wei, March, Keith L, Seppänen-Kaijansinkko, Riitta, Yaszemski, Michael J, Yoo, James J

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Comparison of Poly(l-lactide-co-ɛ-caprolactone) and Poly(trimethylene carbonate) Membranes for Urethral Regeneration: An In Vitro and In Vivo Study by Sartoneva, Reetta, Nordback, Panu H, Haimi, Suvi, Grijpma, Dirk W, Lehto, Kalle, Rooney, Niall, Seppänen-Kaijansinkko, Riitta, Miettinen, Susanna, Lahdes-Vasama, Tuija

“…Urethral defects are normally reconstructed using a patient's own genital tissue; however, in severe cases, additional grafts are needed. We studied the…”
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Monocyte-derived extracellular vesicles involve mesenchymal stem/ stromal cells into tissue remodeling by Gebraad, Arjen, Kaur, Sippy, Kornilov, Roman, Seppänen-Kaijansinkko, Riitta, Mannerström, Bettina

“…Background: Monocytes and osteoclasts share precursors and both provide pro-osteogenic signals to mesenchymal stem/stromal cells (MSCs) and osteoblastic…”
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