Search Results - "Sepiso K Masenga"
-
1
Mechanisms of Oxidative Stress in Metabolic Syndrome
Published in International journal of molecular sciences (26-04-2023)“…Metabolic syndrome is a cluster of conditions associated with the risk of diabetes mellitus type 2 and cardiovascular diseases (CVDs). Metabolic syndrome is…”
Get full text
Journal Article -
2
Salt and Gut Microbiota in Heart Failure
Published in Current hypertension reports (01-08-2023)“…Purpose of Review The role and underlying mechanisms mediated by dietary salt in modulating the gut microbiota and contributing to heart failure (HF) are not…”
Get full text
Journal Article -
3
Salt Taste and Salt Sensitive Hypertension in HIV
Published in Current hypertension reports (01-03-2023)“…Purpose of Review To provide a summary of current literature and propose potential mechanistic models to help us understand the role of HIV…”
Get full text
Journal Article -
4
Severe acute malnutrition among children under the age of 5 years
Published in PloS one (26-08-2024)“…Severe acute malnutrition (SAM) poses a significant threat to child health globally, particularly in low- and middle-income countries. Zambia, like many…”
Get full text
Journal Article -
5
Plasma osteopontin in persons with HIV and the risk for cardiovascular disease
Published in AIDS (London) (01-02-2023)Get full text
Journal Article -
6
Hypertensive heart disease: risk factors, complications and mechanisms
Published in Frontiers in cardiovascular medicine (05-06-2023)“…Hypertensive heart disease constitutes functional and structural dysfunction and pathogenesis occurring primarily in the left ventricle, the left atrium and…”
Get full text
Journal Article -
7
Productivity-adjusted life-years and correlates of uncontrolled hypertension at two health facilities in Zambia
Published in PloS one (07-12-2023)“…Hypertension has in the recent past surfaced as one of the conditions that has a significant impact on workforce productivity in emerging economies. Zambia is…”
Get full text
Journal Article -
8
Erythrocyte sodium buffering capacity status correlates with self-reported salt intake in a population from Livingstone, Zambia
Published in PloS one (02-03-2022)“…Salt impairs endothelial function and increases arterial stiffness independent of blood pressure. The mechanisms are unknown. Recent evidence suggests that…”
Get full text
Journal Article -
9
Association between complete blood-count-based inflammatory scores and hypertension in persons living with and without HIV in Zambia
Published in PloS one (11-11-2024)“…Background Hypertension is a risk factor for cardiovascular events. Inflammation plays an important role in the development of essential hypertension. Studies…”
Get full text
Journal Article -
10
Viral load suppression and HIV-1 drug resistance mutations in persons with HIV on TLD/TAFED in Zambia
Published in PloS one (06-09-2024)“…An increase in the prevalence of HIV drug resistance (HIVDR) has been reported in recent years, especially in persons on non-nucleoside reverse transcriptase…”
Get full text
Journal Article -
11
Prevalence and correlates of Human Papillomavirus infection in females from Southern Province, Zambia: A cross-sectional study
Published in PloS one (01-08-2024)“…Human papillomavirus (HPV) infection is strongly associated with cervical cancer with almost all cases being associated with the infection. Cervical cancer is…”
Get full text
Journal Article -
12
Gut microbiota dependant trimethylamine N-oxide and hypertension
Published in Frontiers in physiology (06-04-2023)“…The human gut microbiota environment is constantly changing and some specific changes influence the host's metabolic, immune, and neuroendocrine functions…”
Get full text
Journal Article -
13
Mechanisms and Cardiorenal Complications of Chronic Anemia in People with HIV
Published in Viruses (01-04-2024)“…Chronic anemia is more prevalent in people living with HIV (PLWH) compared to the general population. The mechanisms that drive chronic anemia in HIV are…”
Get full text
Journal Article -
14
High salt intake and HIV infection on endothelial glycocalyx shedding in salt-sensitive hypertension
Published in Frontiers in cell and developmental biology (16-07-2024)“…The endothelial glycocalyx is closely associated with various physiological and pathophysiological events. Significant modification of the endothelial…”
Get full text
Journal Article -
15
Glycocalyx-Sodium Interaction in Vascular Endothelium
Published in Nutrients (25-06-2023)“…The glycocalyx generally covers almost all cellular surfaces, where it participates in mediating cell-surface interactions with the extracellular matrix as…”
Get full text
Journal Article -
16
Rifampicin resistance in mycobacterium tuberculosis patients using GeneXpert at Livingstone Central Hospital for the year 2015: a cross sectional explorative study
Published in BMC infectious diseases (22-09-2017)“…Since the recent introduction of GeneXepert for the detection of Tuberculosis (TB) drug resistance mutations in both primary resistance and acquired resistance…”
Get full text
Journal Article -
17
Prevalence of low high-density lipoprotein among young adults receiving antiretroviral therapy in Zambia: An opportunity to consider non-communicable diseases in resource-limited settings
Published in PloS one (16-02-2021)“…With the introduction of effective antiretroviral therapy (ART), people living with HIV (PLWH) are surviving longer and are at risk for developing metabolic…”
Get full text
Journal Article -
18
HIV-Host Cell Interactions
Published in Cells (Basel, Switzerland) (09-05-2023)“…The development of antiretroviral drugs (ARVs) was a great milestone in the management of HIV infection. ARVs suppress viral activity in the host cell, thus…”
Get full text
Journal Article -
19
Recent Advances in Microbiota-Associated Metabolites in Heart Failure
Published in Biomedicines (01-08-2023)“…Heart failure is a risk factor for adverse events such as sudden cardiac arrest, liver and kidney failure and death. The gut microbiota and its metabolites are…”
Get full text
Journal Article -
20
Elevated Eosinophils as a Feature of Inflammation Associated With Hypertension in Virally Suppressed People Living With HIV
Published in Journal of the American Heart Association (18-02-2020)“…Background People living with HIV (PLWH) are at increased risk of cardiovascular disease, including hypertension, which persists despite effective plasma viral…”
Get full text
Journal Article