Search Results - "Sepúlveda, M. Rosario"
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Primary Active Ca2+ Transport Systems in Health and Disease
Published in Cold Spring Harbor perspectives in biology (01-02-2020)“…Calcium ions (Ca2+) are prominent cell signaling effectors that regulate a wide variety of cellular processes. Among the different players in Ca2+ homeostasis,…”
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New insights into the role of the endoplasmic reticulum in microglia
Published in Neural regeneration research (01-07-2024)Get full text
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Synthesis, Optical Properties, and Antiproliferative Evaluation of NBD-Triterpene Fluorescent Probes
Published in Journal of natural products (Washington, D.C.) (27-01-2023)“…A fluorescent labeling protocol for hydroxylated natural compounds with promising antitumor properties has been used to synthesize, in yields of 72–86%, 12…”
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Editorial: Cell biology of microglia
Published in Frontiers in cellular neuroscience (19-05-2023)Get full text
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Distribution of intracellular Ca2+-ATPases in the mouse retina and their involvement in light-induced cone degeneration
Published in Biochimica et biophysica acta. Molecular cell research (01-01-2024)“…Calcium signalling is involved in many processes in mammalian retina, from development to mature functions and neurodegeneration. Although proteins involved in…”
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LPS-stimulated microglial cells promote ganglion cell death in organotypic cultures of quail embryo retina
Published in Frontiers in cellular neuroscience (15-03-2023)“…During development microglia colonize the central nervous system (CNS) and play an important role in programmed cell death, not only because of their ability…”
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Intracellular Ca2+- and Mn2+-Transport ATPases
Published in Chemical reviews (01-10-2009)“…VangheIuwe et al discuss the endoplasmic reticulum eukaryotic CA2+-adenosine triphosphatases and Golgi apparatus Ca2+ and Mn2+ ATPases…”
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Silencing the SPCA1 (Secretory Pathway Ca2+-ATPase Isoform 1) Impairs Ca2+ Homeostasis in the Golgi and Disturbs Neural Polarity
Published in The Journal of neuroscience (30-09-2009)“…Neural cell differentiation involves a complex regulatory signal transduction network in which Ca(2+) ions and the secretory pathway play pivotal roles. The…”
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Where is TRPV1 expressed in the bladder, do we see the real channel?
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-04-2009)“…Transient receptor potential channel-vanilloid subfamily member 1 (TRPV1) is an important target in the treatment of bladder overactivity. This receptor is…”
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Impairment of the activity of the plasma membrane Ca²⁺-ATPase in Alzheimer's disease
Published in Biochemical Society transactions (01-06-2011)“…AD (Alzheimer's disease) is an age-associated neurodegenerative disorder where the accumulation of neurotoxic Aβ (amyloid β-peptide) in senile plaques is a…”
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The Plasma Membrane Ca2+-ATPase Isoform 4 Is Localized in Lipid Rafts of Cerebellum Synaptic Plasma Membranes
Published in The Journal of biological chemistry (06-01-2006)“…Here we describe the association of the synaptosomal plasma membrane Ca2+-ATPase (PMCA) from pig cerebellum with cholesterol/sphingomyelin-rich membrane…”
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Functional and immunocytochemical evidence for the expression and localization of the secretory pathway Ca²⁺-ATPase isoform 1 (SPCA1) in cerebellum relative to other Ca²⁺ pumps
Published in Journal of neurochemistry (01-11-2007)“…Membrane fractions of pig cerebellum show Ca²⁺-ATPase activdity and Ca²⁺ transport due to the presence of the secretory pathway Ca²⁺-ATPase (SPCA). The SPCA1…”
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13
Primary Active Ca 2+ Transport Systems in Health and Disease
Published in Cold Spring Harbor perspectives in biology (03-02-2020)“…Calcium ions (Ca ) are prominent cell signaling effectors that regulate a wide variety of cellular processes. Among the different players in Ca homeostasis,…”
Get full text
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Upregulation of the secretory pathway Ca 2+ /Mn 2+ -ATPase isoform 1 in LPS-stimulated microglia and its involvement in Mn 2+ -induced Golgi fragmentation
Published in Glia (01-06-2024)“…Microglia play an important protective role in the healthy nervous tissue, being able to react to a variety of stimuli that induce different intracellular…”
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Efficient In Vitro and In Vivo Anti-Inflammatory Activity of a Diamine-PEGylated Oleanolic Acid Derivative
Published in International journal of molecular sciences (01-08-2021)“…Recent evidence has shown that inflammation can contribute to all tumorigenic states. We have investigated the anti-inflammatory effects of a diamine-PEGylated…”
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Upregulation of the secretory pathway Ca2+/Mn2+‐ATPase isoform 1 in LPS‐stimulated microglia and its involvement in Mn2+‐induced Golgi fragmentation
Published in Glia (01-06-2024)“…Microglia play an important protective role in the healthy nervous tissue, being able to react to a variety of stimuli that induce different intracellular…”
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The endoplasmic reticulum Ca2+‐ATPase SERCA2b is upregulated in activated microglia and its inhibition causes opposite effects on migration and phagocytosis
Published in Glia (01-04-2021)“…Activation of microglia is an early immune response to damage in the brain. Although a key role for Ca2+ as trigger of microglial activation has been…”
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Microglial Phagocytosis During Embryonic and Postnatal Development
Published in Advances in neurobiology (2024)“…Microglia play decisive roles during the development of the central nervous system (CNS). Phagocytosis is one of the classical functions attributed to…”
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Microglia and Microglia-Like Cells: Similar but Different
Published in Frontiers in cellular neuroscience (07-02-2022)“…Microglia are the tissue-resident macrophages of the central nervous parenchyma. In mammals, microglia are thought to originate from yolk sac precursors and…”
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The endoplasmic reticulum Ca 2+ -ATPase SERCA2b is upregulated in activated microglia and its inhibition causes opposite effects on migration and phagocytosis
Published in Glia (01-04-2021)“…Activation of microglia is an early immune response to damage in the brain. Although a key role for Ca as trigger of microglial activation has been considered,…”
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