Search Results - "Seow, Y."

Minimising Embodied Product Energy to support energy efficient manufacturing by Rahimifard, S., Seow, Y., Childs, T.

“…Green sources of power generation and efficient management of energy demand are among the greatest challenges facing manufacturing businesses. A significant…”
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Mechanopharmacology of Rho-kinase antagonism in airway smooth muscle and potential new therapy for asthma by Wang, Lu, Chitano, Pasquale, Seow, Chun Y.

“…[Display omitted] The principle of mechanopharmacology of airway smooth muscle (ASM) is based on the premise that physical agitation, such as pressure…”
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Critical roles of airway smooth muscle in mediating deep-inspiration-induced bronchodilation: a big stretch? by Yasuda, Yuto, Wang, Lu, Chitano, Pasquale, Seow, Chun Y

“…Background Deep inspiration (DI) has been shown to induce bronchodilation and bronchoprotection in bronchochallenged healthy subjects, but not in asthmatics…”
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Characteristics of lung resistance and elastance associated with tracheal stenosis and intrapulmonary airway narrowing in ex vivo sheep lungs by Yasuda, Yuto, Maksym, Geoffrey N, Wang, Lu, Chitano, Pasquale, Seow, Chun Y

“…Understanding the characteristics of pulmonary resistance and elastance in relation to the location of airway narrowing, e.g., tracheal stenosis vs…”
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Prevalence of Internet Addiction and Gaming Disorders in Southeast Asia: A Meta-Analysis by Chia, Doris X Y, Ng, Charis W L, Kandasami, Gomathinayagam, Seow, Mavis Y L, Choo, Carol C, Chew, Peter K H, Lee, Cheng, Zhang, Melvyn W B

“…This meta-analytic review aimed to examine the pooled prevalence rates of Internet addiction and gaming disorders in Southeast Asia. Several databases…”
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p116Rip promotes myosin phosphatase activity in airway smooth muscle cells by Komatsu, Satoshi, Wang, Lu, Seow, Chun Y., Ikebe, Mitsuo

“…Myosin phosphatase‐Rho interacting protein (p116Rip) was originally found as a RhoA‐binding protein. Subsequent studies by us and others revealed that p116Rip…”
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Molecular Events of the Crossbridge Cycle Reflected in the Force-Velocity Relationship of Activated Muscle by Seow, Kathryn N, Seow, Chun Y

“…Muscles convert chemical energy to mechanical work. Mechanical performance of a muscle is often assessed by the muscle's ability to shorten and generate power…”
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Rho-Kinase Inhibition of Active Force and Passive Tension in Airway Smooth Muscle: A Strategy for Treating Airway Hyperresponsiveness in Asthma by Yasuda, Yuto, Wang, Lu, Chitano, Pasquale, Seow, Chun Y

“…Rho-kinase inhibitors have been identified as a class of potential drugs for treating asthma because of their ability to reduce airway inflammation and active…”
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Cellular Biomechanics in Drug Screening and Evaluation: Mechanopharmacology by Krishnan, Ramaswamy, Park, Jin-Ah, Seow, Chun Y, Lee, Peter V-S, Stewart, Alastair G

“…The study of mechanobiology is now widespread. The impact of cell and tissue mechanics on cellular responses is well appreciated. However, knowledge of the…”
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Myosin filament assembly in an ever-changing myofilament lattice of smooth muscle by Seow, Chun Y

“…A major development in smooth muscle research in recent years is the recognition that the myofilament lattice of the muscle is malleable. The malleability…”
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Influence of microRNA deregulation on chaperone-mediated autophagy and α-synuclein pathology in Parkinson's disease by Alvarez-Erviti, L, Seow, Y, Schapira, A HV, Rodriguez-Oroz, M C, Obeso, J A, Cooper, J M

“…The presence of α -synuclein aggregates in the characteristic Lewy body pathology seen in idiopathic Parkinson’s disease (PD), together with α -synuclein gene…”
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Optofluidic variable-focus lenses for light manipulation by Seow, Y C, Lim, S P, Lee, H P

“…This paper presents a planar optofluidic lens for light manipulation utilizing a combination of optofluidic biconvex lens with micromixer. Three light…”
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Purification of Myosin from Bovine Tracheal Smooth Muscle, Filament Formation and Endogenous Association of Its Regulatory Complex by Wang, Lu, Sobieszek, Isabel J, Seow, Chun Y, Sobieszek, Apolinary

“…Dynamic regulation of myosin filaments is a crucial factor in the ability of airway smooth muscle (ASM) to adapt to a wide length range. Increased stability or…”
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Passive stiffness of airway smooth muscle: The next target for improving airway distensibility and treatment for asthma? by Seow, Chun Y

“…Abstract Reduced airway distensibility due to increased airway stiffness is a characteristic of asthma. Airway stiffness is determined by the property and…”
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Steroids to reduce the impact on delirium (STRIDE): a double‐blind, randomised, placebo‐controlled feasibility trial of pre‐operative dexamethasone in people with hip fracture by Kluger, M. T., Skarin, M., Collier, J., Rice, D. A., McNair, P. J., Seow, M.Y., Connolly, M. J.

“…Summary Neuro‐inflammation may be important in the pathogenesis of postoperative delirium following hip fracture surgery. Studies have suggested a potential…”
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The actin regulator zyxin reinforces airway smooth muscle and accumulates in airways of fatal asthmatics by Rosner, Sonia R, Pascoe, Christopher D, Blankman, Elizabeth, Jensen, Christopher C, Krishnan, Ramaswamy, James, Alan L, Elliot, John G, Green, Francis H, Liu, Jeffrey C, Seow, Chun Y, Park, Jin-Ah, Beckerle, Mary C, Paré, Peter D, Fredberg, Jeffrey J, Smith, Mark A

“…Bronchospasm induced in non-asthmatic human subjects can be easily reversed by a deep inspiration (DI) whereas bronchospasm that occurs spontaneously in…”
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Multifunctional Core/Shell Nanoparticles Self-Assembled from pH-Induced Thermosensitive Polymers for Targeted Intracellular Anticancer Drug Delivery by Soppimath, K. S., Liu, L.-H., Seow, W. Y., Liu, S.-Q., Powell, R., Chan, P., Yang, Y. Y.

“…Core/shell nanoparticles that display a pH‐sensitive thermal response, self‐assembled from the amphiphilic tercopolymer,…”
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Serum Response Factor Overexpression, a Double Trouble that May Underlie Airway Hyperresponsiveness in Asthma by Seow, Chun Y

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Vitronectin expression in the airways of subjects with asthma and chronic obstructive pulmonary disease by Salazar-Peláez, Lina M, Abraham, Thomas, Herrera, Ana M, Correa, Mario A, Ortega, Jorge E, Paré, Peter D, Seow, Chun Y

“…Vitronectin, a multifunctional glycoprotein, is involved in coagulation, inhibition of the formation of the membrane attack complex (MAC), cell adhesion and…”
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Gene expression analysis in asthma using a targeted multiplex array by Pascoe, Christopher D, Obeidat, Ma'en, Arsenault, Bryna A, Nie, Yunlong, Warner, Stephanie, Stefanowicz, Dorota, Wadsworth, Samuel J, Hirota, Jeremy A, Jasemine Yang, S, Dorscheid, Delbert R, Carlsten, Chris, Hackett, Tillie L, Seow, Chun Y, Paré, Peter D

“…Gene expression changes in the structural cells of the airways are thought to play a role in the development of asthma and airway hyperresponsiveness. This…”
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