Search Results - "Seong, C.M."

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    Potent inhibition of human tumor p21ras farnesyltransferase by A1A2-lacking p21ras CA1A2X peptidomimetics by Nigam, M, Seong, C M, Qian, Y, Hamilton, A D, Sebti, S M

    Published in The Journal of biological chemistry (05-10-1993)
    “…The ras oncogene product p21ras requires farnesylation and subsequent plasma membrane association for its transforming activity. This key post-translational…”
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    Journal Article
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    Design and structural requirements of potent peptidomimetic inhibitors of p21ras farnesyltransferase by Qian, Y, Blaskovich, M A, Saleem, M, Seong, C M, Wathen, S P, Hamilton, A D, Sebti, S M

    Published in The Journal of biological chemistry (29-04-1994)
    “…Cysteine farnesylation of the ras oncogene product, p21ras, on its carboxyl-terminal CA1A2X box (C = cysteine, A = aliphatic, and X = methionine or serine) is…”
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    Journal Article