Search Results - "Seong, Baik‐Lin"
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Prospects on Repurposing a Live Attenuated Vaccine for the Control of Unrelated Infections
Published in Frontiers in immunology (16-05-2022)“…Live vaccines use attenuated microbes to acquire immunity against pathogens in a safe way. As live attenuated vaccines (LAVs) still maintain infectivity, the…”
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Egg microneedles for transdermal vaccination of inactivated influenza virus
Published in Biomaterials science (13-02-2024)“…The use of dissolving microneedles (DMNs) is a drug delivery technique in which drug dissolution occurs once it is administered into the skin. The skin is a…”
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AB5-Type Toxin as a Pentameric Scaffold in Recombinant Vaccines against the Japanese Encephalitis Virus
Published in Toxins (29-06-2023)“…Japanese encephalitis virus (JEV) is an enveloped icosahedral capsid virus with a prime neutralizing epitope present in E protein domain III (EDIII). E dimers…”
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Virucidal nano-perforator of viral membrane trapping viral RNAs in the endosome
Published in Nature communications (14-01-2019)“…Membrane-disrupting agents that selectively target virus versus host membranes could potentially inhibit a broad-spectrum of enveloped viruses, but currently…”
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Antiviral effect of catechins in green tea on influenza virus
Published in Antiviral research (01-11-2005)“…Polyphenolic compound catechins ((−)-epigallocatechin gallate (EGCG), (−)-epicatechin gallate (ECG) and (−)-epigallocatechin (EGC)) from green tea were…”
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Harnessing Pentameric Scaffold of Cholera Toxin B (CTB) for Design of Subvirion Recombinant Dengue Virus Vaccine
Published in Vaccines (Basel) (01-01-2024)“…Dengue virus is an enveloped virus with an icosahedral assembly of envelope proteins (E). The E proteins are arranged as a head-to-tail homodimer, and domain…”
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Glycosylation of Hemagglutinin and Neuraminidase of Influenza A Virus as Signature for Ecological Spillover and Adaptation among Influenza Reservoirs
Published in Viruses (07-04-2018)“…Glycosylation of the hemagglutinin (HA) and neuraminidase (NA) of the influenza provides crucial means for immune evasion and viral fitness in a host…”
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Efficacy of genotype-matched vaccine against re-emerging genotype V Japanese encephalitis virus
Published in Emerging microbes & infections (01-12-2024)“…Japanese encephalitis (JE), caused by the Japanese encephalitis virus (JEV), is a highly threatening disease with no specific treatment. Fortunately, the…”
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Inactivated Eyedrop Influenza Vaccine Adjuvanted with Poly(I:C) Is Safe and Effective for Inducing Protective Systemic and Mucosal Immunity
Published in PloS one (10-09-2015)“…The eye route has been evaluated as an efficient vaccine delivery routes. However, in order to induce sufficient antibody production with inactivated vaccine,…”
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Comparative Evaluation of Recombinant and Acellular Pertussis Vaccines in a Murine Model
Published in Vaccines (Basel) (01-01-2024)“…Since the 2000s, sporadic outbreaks of whooping cough have been reported in advanced countries, where the acellular pertussis vaccination rate is relatively…”
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Baculovirus Displaying Hemagglutinin Elicits Broad Cross-Protection against Influenza in Mice
Published in PloS one (29-03-2016)“…The widespread influenza virus infection further emphasizes the need for novel vaccine strategies that effectively reduce the impact of epidemic as well as…”
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Structure-Based Design and Synthesis of C‑1- and C‑4-Modified Analogs of Zanamivir as Neuraminidase Inhibitors
Published in Journal of medicinal chemistry (14-02-2013)“…In order to exploit the 430-cavity in the active sites of neuraminidases, 22 zanamivir analogs with C-1 and C-4 modification were synthesized, and their…”
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Discovery and development of anti-HBV agents and their resistance
Published in Molecules (Basel, Switzerland) (27-08-2010)“…Hepatitis B virus (HBV) infection is a prime cause of liver diseases such as hepatitis, cirrhosis and hepatocellular carcinoma. The current drugs clinically…”
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A chimeric thermostable M2e and H3 stalk-based universal influenza A virus vaccine
Published in npj vaccines (29-06-2022)“…We developed a new chimeric M2e and H3 hemagglutinin (HA) stalk protein vaccine (M2e-H3 stalk) by genetic engineering of modified H3 stalk domain conjugated…”
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Cold-Adapted Pandemic 2009 H1N1 Influenza Virus Live Vaccine Elicits Cross-Reactive Immune Responses against Seasonal and H5 Influenza A Viruses
Published in Journal of Virology (01-05-2012)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Thermostable H1 hemagglutinin stem with M2e epitopes provides broad cross-protection against group1 and 2 influenza A viruses
Published in Molecular therapy. Methods & clinical development (08-09-2022)“…Hemagglutinin (HA) stem-based vaccines have limitations in providing broad and effective protection against cross-group influenza viruses, despite being a…”
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Broad-spectrum antiviral effect of Agrimonia pilosa extract on influenza viruses
Published in Microbiology and immunology (01-01-2010)“…ABSTRACT Influenza virus continues to emerge and re‐emerge, posing new threats for humans. Here we tested various Korean medicinal plant extracts for potential…”
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Development of a diagnostic system for detection of specific antibodies and antigens against Middle East respiratory syndrome coronavirus
Published in Microbiology and immunology (01-09-2018)“…ABSTRACT Middle East respiratory syndrome coronavirus (MERS‐CoV) is a single‐stranded RNA virus that causes severe respiratory disease in humans with a high…”
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Sublingual immunization with M2-based vaccine induces broad protective immunity against influenza
Published in PloS one (30-11-2011)“…The ectodomain of matrix protein 2 (M2e) of influenza A virus is a rationale target antigen candidate for the development of a universal vaccine against…”
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Efficacy of single dose of a bivalent vaccine containing inactivated Newcastle disease virus and reassortant highly pathogenic avian influenza H5N1 virus against lethal HPAI and NDV infection in chickens
Published in PloS one (01-03-2013)“…Highly pathogenic avian influenza (HPAI) and Newcastle disease (ND) are 2 devastating diseases of poultry, which cause great economic losses to the poultry…”
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