Search Results - "Seok, Seung Hyeok"
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1
A new era of macrophage-based cell therapy
Published in Experimental & molecular medicine (01-09-2023)“…Macrophages are essential innate immune cells found throughout the body that have protective and pathogenic functions in many diseases. When activated,…”
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Cyclooxygenase-2 inhibition blocks M2 macrophage differentiation and suppresses metastasis in murine breast cancer model
Published in PloS one (07-05-2013)“…Tumor cells are often associated with abundant macrophages that resemble the alternatively activated M2 subset. Tumor-associated macrophages (TAMs) inhibit…”
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Comparison of the effects of empagliflozin and sotagliflozin on a zebrafish model of diabetic heart failure with reduced ejection fraction
Published in Experimental & molecular medicine (01-06-2023)“…The sodium-glucose cotransporter 2 (SGLT2) inhibitor empagliflozin (EMPA) and dual SGLT1/2 inhibitor sotagliflozin (SOTA) are emerging as heart failure (HF)…”
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4
Bone morphogenetic protein 7 induces mesenchymal‐to‐epithelial transition in melanoma cells, leading to inhibition of metastasis
Published in Cancer science (01-11-2009)“…Bone morphogenetic protein (BMP) 7 counteracts physiological epithelial‐to‐mesenchymal transition, a process that is indicative of epithelial plasticity in…”
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Human originated bacteria, Lactobacillus rhamnosus PL60, produce conjugated linoleic acid and show anti-obesity effects in diet-induced obese mice
Published in Biochimica et biophysica acta (01-07-2006)“…Many previous studies have reported that conjugated linoleic acid could be produced by starter culture bacteria, but the effects of the bacteria were not…”
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6
Macrophages in intestinal inflammation and resolution: a potential therapeutic target in IBD
Published in Nature reviews. Gastroenterology & hepatology (01-09-2019)“…Macrophages are the gatekeepers of intestinal immune homeostasis as they discriminate between innocuous antigens and potential pathogens to maintain oral…”
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7
Plant homeodomain finger protein 2 promotes bone formation by demethylating and activating Runx2 for osteoblast differentiation
Published in Cell research (01-10-2014)“…Plant homeodomain finger protein 2 (PHF2), which contains a plant homeodomain and a Jumonji-C domain, is an epigenetic regulator that demethylates lysine 9 in…”
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Taurodeoxycholate Increases the Number of Myeloid-Derived Suppressor Cells That Ameliorate Sepsis in Mice
Published in Frontiers in immunology (18-09-2018)“…Bile acids (BAs) control metabolism and inflammation by interacting with several receptors. Here, we report that intravenous infusion of taurodeoxycholate…”
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Signal transducer and activator of transcription 3 (Stat3) contributes to T‐cell homeostasis by regulating pro‐survival Bcl‐2 family genes
Published in Immunology (01-11-2013)“…Summary The naive T‐cell pool in peripheral lymphoid tissues is fairly stable in terms of number, diversity and functional capabilities in spite of the absence…”
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10
GM-CSF Grown Bone Marrow Derived Cells Are Composed of Phenotypically Different Dendritic Cells and Macrophages
Published in Molecules and cells (01-10-2016)“…Granulocyte-macrophage colony stimulating factor (GM-CSF) has a role in inducing emergency hematopoiesis upon exposure to inflammatory stimuli. Although GM-CSF…”
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11
Metabolic features of macrophages in inflammatory diseases and cancer
Published in Cancer letters (28-01-2018)“…Macrophages are now considered to be important players in various inflammatory diseases as well as tumor progression. Emerging evidence reveals that macrophage…”
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12
Production of specific antibodies against SARS-coronavirus nucleocapsid protein without cross reactivity with human coronaviruses 229E and OC43
Published in Journal of veterinary science (Suwŏn-si, Korea) (01-06-2010)“…Severe acute respiratory syndrome (SARS) is a life-threatening disease for which accurate diagnosis is essential. Although many tools have been developed for…”
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13
Highly expressed recombinant human follicle-stimulating hormone from Chinese hamster ovary cells grown in serum-free medium and its effect on induction of folliculogenesis and ovulation
Published in Fertility and sterility (15-05-2010)“…Objective To develop efficient Chinese hamster ovary (CHO) cells that express recombinant human FSH (rhFSH) in serum-free conditions and to investigate the…”
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14
GM-CSF Grown Bone Marrow Derived Cells Are Composed of Phenotypically Different Dendritic Cells and Macrophages
Published in Molecules and cells (2016)“…Granulocyte-macrophage colony stimulating factor (GM-CSF) has a role in inducing emergency hematopoiesis upon exposure to inflammatory stimuli. Although GM-CSF…”
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15
Comparative absorption, distribution, and excretion of titanium dioxide and zinc oxide nanoparticles after repeated oral administration
Published in Particle and fibre toxicology (26-03-2013)“…The in vivo kinetics of nanoparticles is an essential to understand the hazard of nanoparticles. Here, the absorption, distribution, and excretion patterns of…”
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16
Effect of fluorescent whitening agent on the transcription of cell damage-related genes in zebrafish embryos
Published in Journal of applied toxicology (01-09-2012)“…ABSTRACT 7‐Diethylamino‐4‐methylcoumarin (DEMC) is a fluorescent whitening agent (FWAs). There have been some studies on DEMC's protective effects against…”
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17
Therapeutic potential of histamine H4 receptor antagonist as a preventive treatment for diabetic retinopathy in mice
Published in Scientific reports (30-09-2024)“…Diabetic retinopathy (DR) is a prevalent complication of diabetes, often resulting in vision loss and blindness. Existing treatments primarily aim to control…”
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Cre/loxP‐regulated transgenic zebrafish model for neural progenitor‐specific oncogenic Kras expression
Published in Cancer science (01-01-2010)“…Ras proteins regulate signaling pathways that control many cellular responses, such as proliferation, survival, and differentiation. However, there are…”
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GM-CSF Induces Inflammatory Macrophages by Regulating Glycolysis and Lipid Metabolism
Published in The Journal of immunology (1950) (15-11-2016)“…GM-CSF induces proinflammatory macrophages, but the underlying mechanisms have not been studied thus far. In this study, we investigated the mechanisms of how…”
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Epidemiological study of fowl glioma-inducing virus in chickens in Asia and Germany
Published in Avian pathology (01-01-2012)“…Fowl glioma-inducing virus (FGV), which belongs to avian leukosis virus (ALV) subgroup A, induces fowl glioma. This disease is characterized by multiple…”
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