Search Results - "Seoane, LM"

Ghrelin elicits a marked stimulatory effect on GH secretion in freely-moving rats by Seoane, LM, Tovar, S, Baldelli, R, Arvat, E, Ghigo, E, Casanueva, FF, Dieguez, C

“…Ghrelin is a growth hormone-releasing acylated peptide from stomach. The purified peptide consist of 28 amino acids in which the serine 3 residue is…”
Get full text

Influence of thyroid status and growth hormone deficiency on ghrelin by CAMINOS, J. E, SEOANE, L. M, TOVAR, S. A, CASANUEVA, F. F, DIEGUEZ, C

“…To assess whether some of the alterations in energy homeostasis present in thyroid function disorders and GH deficiency could be mediated by ghrelin. To assess…”
Get full text

Orexin A suppresses in vivo GH secretion by Seoane, LM, Tovar, SA, Perez, D, Mallo, F, Lopez, M, Senaris, R, Casanueva, FF, Dieguez, C

“…BACKGROUND/AIMS: Orexins (OXs) are a newly described family of hypothalamic neuropeptides. Based on the distribution of OX neurons and their receptors in the…”
Get full text

Regulation of serum leptin levels by gonadal function in rats by PINILLA, L, SEOANE, L. M, GONZALEZ, L, CARRO, E, AGUILAR, E, CASANUEVA, F. F, DIEGUEZ, C

“…The aim of this study was to investigate the regulation of serum leptin levels by gender and gonadal steroid milieu. Thus, we measured serum leptin levels by…”
Get full text

Agouti-Related Peptide, Neuropeptide Y, and Somatostatin-Producing Neurons Are Targets for Ghrelin Actions in the Rat Hypothalamus by Seoane, Luisa M, López, Miguel, Tovar, Sulay, Casanueva, Felipe F, Señarís, Rosa, Diéguez, Carlos

“…Ghrelin, the endogenous ligand of the GH secretagogue receptor, acts at central level to elicit GH release and regulate food intake. To elucidate the neural…”
Get full text

Drug development strategies for the treatment of obesity: how to ensure efficacy, safety, andsustainable weight loss by Barja-Fernandez S, Leis R, Casanueva FF, Seoane LM

“…S Barja-Fernandez,1-3 R Leis,2 FF Casanueva,3,4 LM Seoane1,3 1Grupo Fisiopatología Endocrina, 2Departamento de Pediatría, Universidad de Santiago de Compostela…”
Get full text

Drug development strategies for the treatment of obesity: how to ensure efficacy, safety, and sustainable weight loss by Barja-Fernandez, S, Leis, R, Casanueva, F F, Seoane, L M

“…The prevalence of obesity has increased worldwide, and approximately 25%-35% of the adult population is obese in some countries. The excess of body fat is…”
Get full text

A possible role of neuropeptide Y, agouti-related protein and leptin receptor isoforms in hypothalamic programming by perinatal feeding in the rat by LOPEZ, M, SEOANE, L. M, TOVAR, S, GARCIA, M. C, NOGUEIRAS, R, DIEGUEZ, C, SENARIS, R. M

“…Perinatal overfeeding predisposes humans and rats to obesity and diabetes in later life. One classical model for studying the effect of early feeding is…”
Get full text

Hypothalamic levels of NPY, MCH, and prepro‐orexin mRNA during pregnancy and lactation in the rat: role of prolactin by García, M. C., López, M., Gualillo, O., Seoane, L. M., Diéguez, C., Señarís, Rosa Maria

“…ABSTRACT Pregnancy and lactation provide excellent models of physiological hyperphagia and hyper‐prolactinemia. To identify possible factors associated with…”
Get full text

Leptin increases in vivo GH responses to GHRH and GH-releasing peptide-6 in food-deprived rats by Carro, E, Seoane, LM, Senaris, R, Casanueva, FF, Dieguez, C

“…BACKGROUND: Leptin has recently been shown to have a stimulatory effect on basal GH secretion. However, the mechanisms by which leptin exert this effect are…”
Get full text

Effect of Food Restriction on Ghrelin in Normal-Cycling Female Rats and in Pregnancy by Gualillo, Oreste, Caminos, Jorge E., Nogueiras, Rubén, Seoane, Luisa M., Arvat, Eva, Ghigo, Ezio, Casanueva, Felipe F., Diéguez, Carlos

“…Objective: Ghrelin is a 28‐amino‐acid acylated peptide that was recently identified as the endogenous ligand for the growth hormone secretagogue receptor…”
Get full text

Orexin-A regulates growth hormone-releasing hormone mRNA content in a nucleus-specific manner and somatostatin mRNA content in a growth hormone-dependent fashion in the rat hypothalamus by López, Miguel, Seoane, Luisa María, Tovar, Sulay, Nogueiras, Rubén, Diéguez, Carlos, Señarís, Rosa

“…The orexins or hypocretins are two neuropeptides involved in the regulation of diverse biological processes such as feeding, sleep and neuroendocrine function…”
Get full text

Cellular Distribution and Regulation of Ghrelin Messenger Ribonucleic Acid in the Rat Pituitary Gland by Caminos, J. E, Nogueiras, R, Blanco, M, Seoane, L. M, Bravo, S, Alvarez, C. V, García-Caballero, T, Casanueva, F. F, Diéguez, C

“…Ghrelin, a 28-amino-acid acylated peptide, strongly stimulates GH release and food intake. In the present study, we found that ghrelin is expressed in…”
Get full text

Regulation of peptide YY levels by age, hormonal, and nutritional status by Tovar, S.A, Seoane, L.M, Caminos, J.E, Nogueiras, R, Casanueva, F.F, Dieguez, C

“…Objective: Peptide YY (PYY) 3‐36 has recently been recognized as an important gut hormone that influences food intake. Peripheral injections of PYY 3‐36 in…”
Get full text

Regulation of in vivo TSH secretion by leptin by Seoane, Luisa M, Carro, Eva, Tovar, Sulay, Casanueva, Felipe F, Dieguez, Carlos

“…Leptin, the product of the ob gene, is a hormone secreted by adipocytes that regulates food intake and energy expenditure. The hypothalamus–pituitary–thyroid…”
Get full text

Influence of endogenous leptin tone on the estrous cycle and luteinizing hormone pulsatility in female rats by Carro, E, Pinilla, L, Seoane, L M, Considine, R V, Aguilar, E, Casanueva, F F, Dieguez, C

“…Recent data indicate that leptin may well play an important regulatory role in the hypothalamo-pituitary-gonadal axis. In order to further unravel the…”
Get more information

Neuropeptide Y, but not agouti-related peptide or melanin-concentrating hormone, is a target peptide for orexin-A feeding actions in the rat hypothalamus by López, Miguel, Seoane, Luisa María, García, María del Carmen, Diéguez, Carlos, Señarís, Rosa

“…We examined the effects of orexin A on the mRNA levels of neuropeptide Y, agouti-related peptide, melanin-concentrating hormone, prepro-orexin and orexin…”
Get more information

Role of growth hormone (GH)-releasing hormone and somatostatin on leptin-induced GH secretion by Carro, E, Señarís, R M, Seoane, L M, Frohman, L A, Arimura, A, Casanueva, F F, Diéguez, C

“…Leptin is a hormone secreted by the adipocytes that regulates food intake and energy expenditure. It is known that growth hormone (GH) secretion is markedly…”
Get more information

Regulation of somatotroph cell function by the adipose tissue by Dieguez, C, Carro, E, Seoane, L M, Garcia, M, Camina, J P, Senaris, R, Popovic, V, Casanueva, F F

“…Obese subjects exhibit a marked decrease in plasma growth hormone (GH) levels. However, the mechanisms by which increased adiposity leads to an impairment of…”
Get full text

Interaction between leptin and neuropeptide Y on in vivo growth hormone secretion by Carro, E, Seoane, L M, Señaris, R, Considine, R V, Casanueva, F F, Dieguez, C

“…Leptin, the product of the ob gene, is a recently discovered hormone secreted by adipocytes that regulates food intake and energy expenditure. Leptin has…”
Get more information