Search Results - "Seoane, L. M"

Uroguanylin levels in intestine and plasma are regulated by nutritional status in a leptin-dependent manner by Folgueira, C, Sanchez-Rebordelo, E, Barja-Fernandez, S, Leis, R, Tovar, S, Casanueva, F. F, Dieguez, C, Nogueiras, R, Seoane, L. M

“…PURPOSE: Uroguanylin (UGN) is a 16 amino acid peptide produced mainly by intestinal epithelial cells. Nutrients intake increases circulating levels of…”
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Ghrelin elicits a marked stimulatory effect on GH secretion in freely-moving rats by Seoane, LM, Tovar, S, Baldelli, R, Arvat, E, Ghigo, E, Casanueva, FF, Dieguez, C

“…Ghrelin is a growth hormone-releasing acylated peptide from stomach. The purified peptide consist of 28 amino acids in which the serine 3 residue is…”
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Hypothalamic levels of NPY, MCH, and prepro‐orexin mRNA during pregnancy and lactation in the rat: role of prolactin by García, M. C., López, M., Gualillo, O., Seoane, L. M., Diéguez, C., Señarís, Rosa Maria

“…ABSTRACT Pregnancy and lactation provide excellent models of physiological hyperphagia and hyper‐prolactinemia. To identify possible factors associated with…”
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A possible role of neuropeptide Y, agouti-related protein and leptin receptor isoforms in hypothalamic programming by perinatal feeding in the rat by LOPEZ, M, SEOANE, L. M, TOVAR, S, GARCIA, M. C, NOGUEIRAS, R, DIEGUEZ, C, SENARIS, R. M

“…Perinatal overfeeding predisposes humans and rats to obesity and diabetes in later life. One classical model for studying the effect of early feeding is…”
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Peripheral Endocannabinoid System-Mediated Actions of Rimonabant on Growth Hormone Secretion are Ghrelin-Dependent by Al-Massadi, O., Gabellieri, E., Trujillo, M. L ., Señaris, R., Pagotto, U., Pasquali, R., Casanueva, F. F., Seoane, L . M.

“…The somatotroph axis is a crucial pathway regulating metabolism. Despite the fact that the endocannabinoid system has been also revealed as a potent modulator…”
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Age, sex, and lactating status regulate ghrelin secretion and GOAT mRNA levels from isolated rat stomach by Al-Massadi, O, Crujeiras, A B, González, R C, Pardo, M, Diéguez, C, Casanueva, F F, Seoane, L M

“…Ghrelin is a stomach derivate peptide involved in energy homeostasis regulation, and ghrelin O-acyltransferase (GOAT) is the enzyme responsible for ghrelin…”
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Macronutrients act directly on the stomach to regulate gastric ghrelin release by Al Massadi, O., Pardo, M., Roca-Rivada, A., Castelao, C., Casanueva, F. F., Seoane Camino, L. M.

“…Background : Ghrelin is a gastric secreted hormone deeply implicated in meal initiation and body weight regulation. This peptide is a peripheral orexigenic…”
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Perinatal overfeeding in rats results in increased levels of plasma leptin but unchanged cerebrospinal leptin in adulthood by LOPEZ, M, TOVAR, S, VAZQUEZ, M. J, NOGUEIRAS, R, SEOANE, L. M, GARCIA, M, SENARIS, R. M, DIEGUEZ, C

“…To study the effect of perinatal programming and overfeeding on the hypothalamic control mechanisms of food intake in adult rats. Neonatal programming effects…”
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Growth hormone and somatostatin directly inhibit gastric ghrelin secretion. An in vitro organ culture system by Seoane, L M, Al-Massadi, O, Barreiro, F, Dieguez, C, Casanueva, F F

“…Ghrelin is a 28-amino-acid hormone produced mainly by the stomach which strongly promotes food intake. It is the only known peripheral orexigenic hormone that…”
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The vagus nerve as a regulator of growth hormone secretion by Al-Massadi, O., Trujillo, M.L., Señaris, R., Pardo, M., Castelao, C., Casanueva, F.F., Seoane, L.M.

“…The growth hormone (GH) axis is mainly regulated by the growth hormone releasing hormone (GHRH) and somatostatin (SS) hypothalamic peptides. Nevertheless,…”
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Influence of thyroid status and growth hormone deficiency on ghrelin by CAMINOS, J. E, SEOANE, L. M, TOVAR, S. A, CASANUEVA, F. F, DIEGUEZ, C

“…To assess whether some of the alterations in energy homeostasis present in thyroid function disorders and GH deficiency could be mediated by ghrelin. To assess…”
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Orexin A suppresses in vivo GH secretion by Seoane, LM, Tovar, SA, Perez, D, Mallo, F, Lopez, M, Senaris, R, Casanueva, FF, Dieguez, C

“…BACKGROUND/AIMS: Orexins (OXs) are a newly described family of hypothalamic neuropeptides. Based on the distribution of OX neurons and their receptors in the…”
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Drug development strategies for the treatment of obesity: how to ensure efficacy, safety, and sustainable weight loss by Barja-Fernandez, S, Leis, R, Casanueva, F F, Seoane, L M

“…The prevalence of obesity has increased worldwide, and approximately 25%-35% of the adult population is obese in some countries. The excess of body fat is…”
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Cellular Distribution and Regulation of Ghrelin Messenger Ribonucleic Acid in the Rat Pituitary Gland by Caminos, J. E, Nogueiras, R, Blanco, M, Seoane, L. M, Bravo, S, Alvarez, C. V, García-Caballero, T, Casanueva, F. F, Diéguez, C

“…Ghrelin, a 28-amino-acid acylated peptide, strongly stimulates GH release and food intake. In the present study, we found that ghrelin is expressed in…”
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Regulation of serum leptin levels by gonadal function in rats by PINILLA, L, SEOANE, L. M, GONZALEZ, L, CARRO, E, AGUILAR, E, CASANUEVA, F. F, DIEGUEZ, C

“…The aim of this study was to investigate the regulation of serum leptin levels by gender and gonadal steroid milieu. Thus, we measured serum leptin levels by…”
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Gastric GDF15 levels are regulated by age, sex, and nutritional status in rodents and humans by Pena-Leon, V., Perez-Lois, R., Villalon, M., Folgueira, C., Barja-Fernández, S., Prida, E., Baltar, J., Santos, F., Fernø, J., García-Caballero, T., Nogueiras, R., Quiñones, M., Al-Massadi, O., Seoane, L. M.

“…Aim Growth differentiation factor 15 (GDF15) is a stress response cytokine that has been proposed as a relevant metabolic hormone. Descriptive studies have…”
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Secreted factors derived from obese visceral adipose tissue regulate the expression of breast malignant transformation genes by Crujeiras, A B, Cabia, B, Carreira, M C, Amil, M, Cueva, J, Andrade, S, Seoane, L M, Pardo, M, Sueiro, A, Baltar, J, Morais, T, Monteiro, M P, Lopez-Lopez, R, Casanueva, F F

“…Background/Objectives: Obese adipose tissue, especially the visceral depot, exhibits altered production of several molecules that could have a role on the…”
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Uroguanylin: a new actor in the energy balance movie by Folgueira, C, Barja-Fernandez, S, Gonzalez-Saenz, P, Pena-Leon, V, Castelao, C, Ruiz-Piñon, M, Casanueva, F F, Nogueiras, R, Seoane, L M

“…Uroguanylin (UGN) is a potential target in the fight against obesity. The mature protein is released after enzymatic cleavage from its natural precursor,…”
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FNDC5 is produced in the stomach and associated to body composition by Barja-Fernández, S., Folgueira, C., Castelao, C., Al-Massadi, O., Bravo, S. B., Garcia-Caballero, T., Leis, R., Pardo, M., Casanueva, F. F., Seoane, L. M.

“…The fibronectin type III domain-containing protein 5 (FNDC5) discovered in 2002 has recently gained attention due to its potential role in protecting against…”
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Central obestatin administration does not modify either spontaneous or ghrelin-induced food intake in rats by Seoane, L M, Al-Massadi, O, Pazos, Y, Pagotto, U, Casanueva, F F

“…The isolation of ghrelin unveiled a new system implicated in food intake regulation. The recently isolated hormone obestatin derives from the same precursor of…”
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