Search Results - "Seo, Sung‐Yum"

Design, synthesis, kinetic mechanism and molecular docking studies of novel 1-pentanoyl-3-arylthioureas as inhibitors of mushroom tyrosinase and free radical scavengers by Larik, Fayaz Ali, Saeed, Aamer, Channar, Pervaiz Ali, Muqadar, Urooj, Abbas, Qamar, Hassan, Mubashir, Seo, Sung-Yum, Bolte, Michael

“…A series of novel 1-pentanoyl-3-arylthioureas was designed as new mushroom tyrosinase inhibitors and free radical scavengers. The title compounds were obtained…”
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A Brief Review on Fluorescent Copper Sensor Based on Conjugated Organic Dyes by Saleem, Muhammad, Rafiq, Muhammad, Hanif, Muhammad, Shaheen, Muhammad Ashraf, Seo, Sung-Yum

“…The design and development of the fluorescence reporting molecules for the trace recognition of the metallic ions in the aqueous, mixed organic aqueous media,…”
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Synthesis, kinetic mechanism and docking studies of vanillin derivatives as inhibitors of mushroom tyrosinase by Ashraf, Zaman, Rafiq, Muhammad, Seo, Sung-Yum, Babar, Mustafeez Mujtaba, Zaidi, Najam-us-Sahar Sadaf

“…[Display omitted] The purpose of the present study was to discover the extent of contribution to antityrosinase activity by adding hydroxy substituted benzoic…”
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Exploration of Novel Human Tyrosinase Inhibitors by Molecular Modeling, Docking and Simulation Studies by Hassan, Mubashir, Ashraf, Zaman, Abbas, Qamar, Raza, Hussain, Seo, Sung-Yum

“…Research studies on human tyrosinase inhibitors and exploration for better cytotoxic agents remain an important line in drug discovery and development at the…”
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The exploration of novel Alzheimer’s therapeutic agents from the pool of FDA approved medicines using drug repositioning, enzyme inhibition and kinetic mechanism approaches by Hassan, Mubashir, Raza, Hussain, Abbasi, Muhammad Athar, Moustafa, Ahmed A., Seo, Sung-Yum

“…[Display omitted] •Drug repositioning approach was used to predict the possible therapeutic effects of FDA approved drugs against AD disease.•The screened…”
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Hybrid Pharmacophoric Approach in the Design and Synthesis of Coumarin Linked Pyrazolinyl as Urease Inhibitors, Kinetic Mechanism and Molecular Docking by Saeed, Aamer, Mahesar, Parvez Ali, Channar, Pervaiz Ali, Larik, Fayaz Ali, Abbas, Qamar, Hassan, Mubashir, Raza, Hussain, Seo, Sung‐Yum

“…The current research article reports the synthesis of coumarinyl pyrazolinyl thioamide derivatives and their biological activity as inhibitors of jack bean…”
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Novel 1,3‐oxazine‐tetrazole hybrids as mushroom tyrosinase inhibitors and free radical scavengers: Synthesis, kinetic mechanism, and molecular docking studies by Qamar, Rabia, Saeed, Aamer, Larik, Fayaz Ali, Abbas, Qamar, Hassan, Mubashir, Raza, Hussain, Seo, Sung‐Yum

“…A variety of 5‐(2H‐tetrazol‐5‐yl)‐4‐thioxo‐2‐(substituted phenyl)‐4,5‐dihydro‐1,3‐oxazin‐6‐ones (3a–k) have been synthesized from 1,3‐oxazine‐5‐carbonitriles…”
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Novel C-2 Symmetric Molecules as α-Glucosidase and α-Amylase Inhibitors: Design, Synthesis, Kinetic Evaluation, Molecular Docking and Pharmacokinetics by Shahzad, Danish, Saeed, Aamer, Larik, Fayaz Ali, Channar, Pervaiz Ali, Abbas, Qamar, Alajmi, Mohamed F, Arshad, M Ifzan, Erben, Mauricio F, Hassan, Mubashir, Raza, Hussain, Seo, Sung-Yum, El-Seedi, Hesham R

“…A series of symmetrical salicylaldehyde-bishydrazine azo molecules, - , have been synthesized, characterized by H-NMR and C-NMR, and evaluated for their in…”
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Design and Synthesis of New Porphyrin Analogues as Potent Photosensitizers for Photodynamic Therapy: Spectroscopic Approach by Mahajan, Prasad G., Dige, Nilam C., Vanjare, Balasaheb D., Kim, Chong-Hyeak, Seo, Sung-Yum, Lee, Ki Hwan

“…New porphyrin analogues have been designed and synthesized using pyrrole, various aldehydes and propionic acid. The formation of desired compounds was analyzed…”
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Sulfonamide-Linked Ciprofloxacin, Sulfadiazine and Amantadine Derivatives as a Novel Class of Inhibitors of Jack Bean Urease; Synthesis, Kinetic Mechanism and Molecular Docking by Channar, Pervaiz Ali, Saeed, Aamer, Albericio, Fernando, Larik, Fayaz Ali, Abbas, Qamar, Hassan, Mubashir, Raza, Hussain, Seo, Sung-Yum

“…Sulfonamide derivatives serve as an important building blocks in the drug design discovery and development (4D) process. Ciprofloxacin-, sulfadiazine- and…”
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Novel 1,2,4-triazole analogues as mushroom tyrosinase inhibitors: synthesis, kinetic mechanism, cytotoxicity and computational studies by Vanjare, Balasaheb D., Mahajan, Prasad G., Dige, Nilam C., Raza, Hussain, Hassan, Mubashir, Han, Yohan, Kim, Song Ja, Seo, Sung-Yum, Lee, Ki Hwan

“…We have created a novel series of mushroom tyrosinase inhibitors with 1,2,4-triazole as fundamental skeleton. The target compound 1,2,4-triazol-3-ylthio)- N…”
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Acetazolamide Inhibits the Level of Tyrosinase and Melanin: An Enzyme Kinetic, In Vitro, In Vivo, and In Silico Studies by Abbas, Qamar, Raza, Hussain, Hassan, Mubashir, Phull, Abdul Rehman, Kim, Song Ja, Seo, Sung‐Yum

“…Melanin is the major factor that determines skin color and protects from ultraviolet radiation. In present study we evaluated the anti‐melanogenesis effect of…”
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Synthesis and biological evaluation of 1,2,4-triazolidine-3-thiones as potent acetylcholinesterase inhibitors: in vitro and in silico analysis through kinetics, chemoinformatics and computational approaches by Mahajan, Prasad G., Dige, Nilam C., Vanjare, Balasaheb D., Raza, Hussain, Hassan, Mubashir, Seo, Sung-Yum, Kim, Chong- Hyeak, Lee, Ki Hwan

“…We have designed and synthesized a novel acidic ionic liquid and explored its catalytic efficiency for the synthesis of 1,2,4-triazolidine-3-thione…”
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Drug-1,3,4-Thiadiazole Conjugates as Novel Mixed-Type Inhibitors of Acetylcholinesterase: Synthesis, Molecular Docking, Pharmacokinetics, and ADMET Evaluation by Ujan, Rabail, Saeed, Aamer, Channar, Pervaiz Ali, Larik, Fayaz Ali, Abbas, Qamar, Alajmi, Mohamed F, El-Seedi, Hesham R, Rind, Mahboob Ali, Hassan, Mubashir, Raza, Hussain, Seo, Sung-Yum

“…A small library of new drug-1,3,4-thiazidazole hybrid compounds ( ⁻ ) was synthesized, characterized, and assessed for their acetyl cholinesterase enzyme…”
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An expedient synthesis of N‐(1‐(5‐mercapto‐4‐((substituted benzylidene)amino)‐4H‐1,2,4‐triazol‐3‐yl)‐2‐phenylethyl)benzamides as jack bean urease inhibitors and free radical scavengers: Kinetic mechanism and molecular docking studies by Saeed, Aamer, Larik, Fayaz Ali, Channar, Pervaiz Ali, Mehfooz, Haroon, Ashraf, Mohammad Haseeb, Abbas, Qamar, Hassan, Mubashir, Seo, Sung‐Yum

“…In this study, some new azomethine‐triazole hybrids 5a–5l derived from N‐benzoyl‐L‐phenylalanine were synthesized and characterized. The synthesized compounds…”
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Development of highly potent melanogenesis inhibitor by in vitro, in vivo and computational studies by Abbas, Qamar, Ashraf, Zaman, Hassan, Mubashir, Nadeem, Humaira, Latif, Muhammad, Afzal, Samina, Seo, Sung-Yum

“…The present work describes the synthesis of few hydroxylated amide derivatives as melanogenesis inhibitors. In vitro, in vivo and computational studies proved…”
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Symmetrical Heterocyclic Cage Skeleton: Synthesis, Urease Inhibition Activity, Kinetic Mechanistic Insight, and Molecular Docking Analyses by Hanif, Muhammad, Kanwal, Fariha, Rafiq, Muhammad, Hassan, Mubashir, Mustaqeem, Muhammad, Seo, Sung-Yum, Zhang, Yunlong, Lu, Changrui, Chen, Ting, Saleem, Muhammad

“…The present study focuses on the design and synthesis of a cage-like organic skeleton containing two triazole rings jointed via imine linkage. These molecules…”
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Extending the scope of amantadine drug by incorporation of phenolic azo Schiff bases as potent selective inhibitors of carbonic anhydrase II, drug‐likeness and binding analysis by Channar, Pervaiz A., Saeed, Aamer, Shahzad, Danish, Larik, Fayaz Ali, Hassan, Mubashir, Raza, Hussain, Abbas, Qamar, Seo, Sung‐Yum

“…A series of Amantadine‐based azo Schiff base dyes 6a–6e have been synthesized and characterized by 1H NMR and 13C NMR and evaluated for their in vitro carbonic…”
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Iminothiazoline-Sulfonamide Hybrids as Jack Bean Urease Inhibitors; Synthesis, Kinetic Mechanism and Computational Molecular Modeling by Saeed, Aamer, Mahmood, Shams-ul, Rafiq, Muhammad, Ashraf, Zaman, Jabeen, Farukh, Seo, Sung-Yum

“…The present work reports the synthesis of several 2‐iminothiazoline derivatives of sulfanilamide (3a–j) as inhibitors of jack bean ureases. The title compounds…”
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Convergent synthesis of carbonic anhydrase inhibiting bi‐heterocyclic benzamides: Structure–activity relationship and mechanistic explorations through enzyme inhibition, kinetics, and computational studies by Khan, Farhan M., Abbasi, Muhammad A., Aziz‐ur‐Rehman, Siddiqui, Sabahat Z., Sadiq Butt, Abdul R., Raza, Hussain, Zafar, Ayesha, Ali Shah, Syed A., Shahid, Muhammad, Seo, Sung‐Yum

“…By using a convergent methodology, a novel series of N‐arylated 4‐yl‐benzamides containing a bi‐heterocyclic thiazole–triazole core was synthesized, and the…”
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