Search Results - "Seo, Keunhee"

SREBP and MDT-15 protect C. elegans from glucose-induced accelerated aging by preventing accumulation of saturated fat by Lee, Dongyeop, Jeong, Dae-Eun, Son, Heehwa G, Yamaoka, Yasuyo, Kim, Hyunmin, Seo, Keunhee, Khan, Abdul Aziz, Roh, Tae-Young, Moon, Dae Won, Lee, Youngsook, Lee, Seung-Jae V

“…Glucose-rich diets shorten the life spans of various organisms. However, the metabolic processes involved in this phenomenon remain unknown. Here, we show that…”
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RNA surveillance via nonsense-mediated mRNA decay is crucial for longevity in daf-2/insulin/IGF-1 mutant C. elegans by Son, Heehwa G., Seo, Mihwa, Ham, Seokjin, Hwang, Wooseon, Lee, Dongyeop, An, Seon Woo A., Artan, Murat, Seo, Keunhee, Kaletsky, Rachel, Arey, Rachel N., Ryu, Youngjae, Ha, Chang Man, Kim, Yoon Ki, Murphy, Coleen T., Roh, Tae-Young, Nam, Hong Gil, Lee, Seung-Jae V.

“…Long-lived organisms often feature more stringent protein and DNA quality control. However, whether RNA quality control mechanisms, such as nonsense-mediated…”
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RNA helicase HEL-1 promotes longevity by specifically activating DAF-16/FOXO transcription factor signaling in Caenorhabditis elegans by Seo, Mihwa, Seo, Keunhee, Hwang, Wooseon, Koo, Hee Jung, Hahm, Jeong-Hoon, Yang, Jae-Seong, Han, Seong Kyu, Hwang, Daehee, Kim, Sanguk, Jang, Sung Key, Lee, Yoontae, Nam, Hong Gil, Lee, Seung-Jae V

“…The homeostatic maintenance of the genomic DNA is crucial for regulating aging processes. However, the role of RNA homeostasis in aging processes remains…”
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KIN‐4/MAST kinase promotes PTEN‐mediated longevity of Caenorhabditis elegans via binding through a PDZ domain by An, Seon Woo A., Choi, Eun‐Seok, Hwang, Wooseon, Son, Heehwa G., Yang, Jae‐Seong, Seo, Keunhee, Nam, Hyun‐Jun, Nguyen, Nhung T. H., Kim, Eun Ji E., Suh, Bo Kyoung, Kim, Youngran, Nakano, Shunji, Ryu, Youngjae, Man Ha, Chang, Mori, Ikue, Park, Sang Ki, Yoo, Joo‐Yeon, Kim, Sanguk, Lee, Seung‐Jae V.

“…PDZ domain‐containing proteins (PDZ proteins) act as scaffolds for protein–protein interactions and are crucial for a variety of signal transduction processes…”
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Heat shock factor 1 mediates the longevity conferred by inhibition of TOR and insulin/IGF‐1 signaling pathways in C. elegans by Seo, Keunhee, Choi, Eunseok, Lee, Dongyeop, Jeong, Dae‐Eun, Jang, Sung Key, Lee, Seung‐Jae

“…Summary Target of rapamycin (TOR) signaling is an evolutionarily well‐conserved pathway that regulates various physiologic processes, including aging and…”
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eIF2A, an initiator tRNA carrier refractory to eIF2α kinases, functions synergistically with eIF5B by Kim, Eunah, Kim, Joon Hyun, Seo, Keunhee, Hong, Ka Young, An, Seon Woo A., Kwon, Junyoung, Lee, Seung-Jae V., Jang, Sung Key

“…The initiator tRNA (Met-tRNA i Met ) at the P site of the small ribosomal subunit plays an important role in the recognition of an mRNA start codon. In…”
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Mitochondrial chaperone HSP‐60 regulates anti‐bacterial immunity via p38 MAP kinase signaling by Jeong, Dae‐Eun, Lee, Dongyeop, Hwang, Sun‐Young, Lee, Yujin, Lee, Jee‐Eun, Seo, Mihwa, Hwang, Wooseon, Seo, Keunhee, Hwang, Ara B, Artan, Murat, Son, Heehwa G, Jo, Jay‐Hyun, Baek, Haeshim, Oh, Young Min, Ryu, Youngjae, Kim, Hyung‐Jun, Ha, Chang Man, Yoo, Joo‐Yeon, Lee, Seung‐Jae V

“…Mitochondria play key roles in cellular immunity. How mitochondria contribute to organismal immunity remains poorly understood. Here, we show that…”
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Prefoldin 6 mediates longevity response from heat shock factor 1 to FOXO in C. elegans by Son, Heehwa G, Seo, Keunhee, Seo, Mihwa, Park, Sangsoon, Ham, Seokjin, An, Seon Woo A, Choi, Eun-Seok, Lee, Yujin, Baek, Haeshim, Kim, Eunju, Ryu, Youngjae, Ha, Chang Man, Hsu, Ao-Lin, Roh, Tae-Young, Jang, Sung Key, Lee, Seung-Jae V

“…Heat shock factor 1 (HSF-1) and forkhead box O (FOXO) are key transcription factors that protect cells from various stresses. In , HSF-1 and FOXO together…”
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RNA helicase HEL-1 promotes longevity by specifically activating DAF-16/FOXO transcription factor signaling inCaenorhabditis elegans by Seo, Mihwa, Seo, Keunhee, Hwang, Wooseon, Koo, Hee Jung, Hahm, Jeong-Hoon, Yang, Jae-Seong, Han, Seong Kyu, Hwang, Daehee, Kim, Sanguk, Jang, Sung Key, Lee, Yoontae, Nam, Hong Gil, Lee, Seung-Jae V.

“…The homeostatic maintenance of the genomic DNA is crucial for regulating aging processes. However, the role of RNA homeostasis in aging processes remains…”
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MON-2, a Golgi protein, mediates autophagy-dependent longevity in Caenorhabditis elegans by Jung, Yoonji, Artan, Murat, Kim, Nari, Yeom, Jeonghun, Hwang, Ara B, Jeong, Dae-Eun, Altintas, Özlem, Seo, Keunhee, Seo, Mihwa, Lee, Dongyeop, Hwang, Wooseon, Lee, Yujin, Sohn, Jooyeon, Kim, Eun Ji E, Ju, Sungeun, Han, Seong Kyu, Nam, Hyun-Jun, Adams, Linnea, Ryu, Youngjae, Moon, Dong Jin, Kang, Chanhee, Yoo, Joo-Yeon, Park, Sang Ki, Ha, Chang Man, Hansen, Malene, Kim, Sanguk, Lee, Cheolju, Park, Seung-Yeol, Lee, Seung-Jae V

“…The Golgi apparatus plays a central role in trafficking cargoes such as proteins and lipids. Defects in the Golgi apparatus lead to various diseases, but its…”
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Regulation of lifespan by chemosensory and thermosensory systems: findings in invertebrates and their implications in mammalian aging by Jeong, Dae-Eun, Artan, Murat, Seo, Keunhee, Lee, Seung-Jae

“…Many environmental factors that dynamically change in nature influence various aspects of animal physiology. Animals are equipped with sensory neuronal systems…”
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