Search Results - "Seo, Jinho"

Necroptosis molecular mechanisms: Recent findings regarding novel necroptosis regulators by Seo, Jinho, Nam, Young Woo, Kim, Seongmi, Oh, Doo-Byoung, Song, Jaewhan

“…Necroptosis is a form of programmed necrosis that is mediated by various cytokines and pattern recognition receptors (PRRs). Cells dying by necroptosis show…”
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Fluorescent bioimaging of pH: from design to applications by Hou, Ji-Ting, Ren, Wen Xiu, Li, Kun, Seo, Jinho, Sharma, Amit, Yu, Xiao-Qi, Kim, Jong Seung

“…Protons play crucial roles in many physiological and pathological processes, such as receptor-mediated signal transduction, ion transport, endocytosis,…”
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Polyunsaturated fatty acid biosynthesis pathway determines ferroptosis sensitivity in gastric cancer by Lee, Ji-Yoon, Nam, Miso, Son, Hye Young, Hyun, Kwangbeom, Jang, Seo Young, Kim, Jong Woo, Kim, Min Wook, Jung, Youngae, Jang, Eunji, Yoon, Seon-Jin, Kim, Jungeun, Kim, Jihye, Seo, Jinho, Min, Jeong-Ki, Oh, Kyoung-Jin, Han, Baek-Soo, Kim, Won Kon, Bae, Kwang-Hee, Song, Jaewhan, Kim, Jaehoon, Huh, Yong-Min, Hwang, Geum-Sook, Lee, Eun-Woo, Lee, Sang Chul

“…Ferroptosis is an iron-dependent regulated necrosis mediated by lipid peroxidation. Cancer cells survive under metabolic stress conditions by altering lipid…”
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Rational Design of in Vivo Tau Tangle-Selective Near-Infrared Fluorophores: Expanding the BODIPY Universe by Verwilst, Peter, Kim, Hye-Ri, Seo, Jinho, Sohn, Nak-Won, Cha, Seung-Yun, Kim, Yeongmin, Maeng, Sungho, Shin, Jung-Won, Kwak, Jong Hwan, Kang, Chulhun, Kim, Jong Seung

“…The elucidation of the cause of Alzheimer’s disease remains one of the greatest questions in neurodegenerative research. The lack of highly reliable low-cost…”
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Mannose-6-phosphate glycan for lysosomal targeting: various applications from enzyme replacement therapy to lysosome-targeting chimeras by Seo, Jinho, Oh, Doo-Byoung

“…A lysosome, an acidic membrane-bound organelle, contains hydrolytic enzymes to digest macromolecules for recycling. Many lysosomal enzymes (LEs) traffic to the…”
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CHIP controls necroptosis through ubiquitylation- and lysosome-dependent degradation of RIPK3 by Seo, Jinho, Lee, Eun-Woo, Sung, Hyerim, Seong, Daehyeon, Dondelinger, Yves, Shin, Jihye, Jeong, Manhyung, Lee, Hae-Kyung, Kim, Jung-Hoon, Han, Su Yeon, Lee, Cheolju, Seong, Je Kyung, Vandenabeele, Peter, Song, Jaewhan

“…Receptor-interacting protein kinase 3 (RIPK3) functions as a key regulator of necroptosis. Here, we report that the RIPK3 expression level is negatively…”
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Beclin 1 functions as a negative modulator of MLKL oligomerisation by integrating into the necrosome complex by Seo, Jinho, Seong, Daehyeon, Nam, Young Woo, Hwang, Chi Hyun, Lee, Seung Ri, Lee, Choong-Sil, Jin, Young, Lee, Han-Woong, Oh, Doo-Byoung, Vandenabeele, Peter, Song, Jaewhan

“…Necroptosis is a form of regulated cell death caused by formation of the necrosome complex. However, the factors modulating this process and the systemic…”
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The lipoprotein-associated phospholipase A2 inhibitor Darapladib sensitises cancer cells to ferroptosis by remodelling lipid metabolism by Oh, Mihee, Jang, Seo Young, Lee, Ji-Yoon, Kim, Jong Woo, Jung, Youngae, Kim, Jiwoo, Seo, Jinho, Han, Tae-Su, Jang, Eunji, Son, Hye Young, Kim, Dain, Kim, Min Wook, Park, Jin-Sung, Song, Kwon-Ho, Oh, Kyoung-Jin, Kim, Won Kon, Bae, Kwang-Hee, Huh, Yong-Min, Kim, Soon Ha, Kim, Doyoun, Han, Baek-Soo, Lee, Sang Chul, Hwang, Geum-Sook, Lee, Eun-Woo

“…Arachidonic and adrenic acids in the membrane play key roles in ferroptosis. Here, we reveal that lipoprotein-associated phospholipase A2 (Lp-PLA2) controls…”
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Structural basis for proapoptotic activation of Bak by the noncanonical BH3-only protein Pxt1 by Lim, Dahwan, Choe, So-Hui, Jin, Sein, Lee, Seulgi, Kim, Younjin, Shin, Ho-Chul, Choi, Joon Sig, Oh, Doo-Byoung, Kim, Seung Jun, Seo, Jinho, Ku, Bonsu

“…Bak is a critical executor of apoptosis belonging to the Bcl-2 protein family. Bak contains a hydrophobic groove where the BH3 domain of proapoptotic Bcl-2…”
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Antibody-secreting macrophages generated using CpG-free plasmid eliminate tumor cells through antibody-dependent cellular phagocytosis by Cha, Eun Bi, Shin, Keun Koo, Seo, Jinho, Oh, Doo-Byoung

“…The non-viral delivery of genes into macrophages, known as hard-to-transfect cells, is a challenge. In this study, the microporation of a CpG-free and small…”
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Multifaceted C-terminus of HSP70-interacting protein regulates tumorigenesis via protein quality control by Seo, Jinho, Han, Su Yeon, Seong, Daehyeon, Han, Hyun-Ji, Song, Jaewhan

“…C-terminus of heat shock protein 70 (HSP70)-interacting protein (CHIP) is an E3 ligase involved in a variety of protein homeostasis events implicated in…”
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Molecular Chaperone HSP90 Is Necessary to Prevent Cellular Senescence via Lysosomal Degradation of p14ARF by Han, Su Yeon, Ko, Aram, Kitano, Haruhisa, Choi, Chel Hun, Lee, Min-Sik, Seo, Jinho, Fukuoka, Junya, Kim, Soo-Youl, Hewitt, Stephen M, Chung, Joon-Yong, Song, Jaewhan

“…The tumor suppressor function of p14ARF is regulated at a posttranslational level via mechanisms yet to be fully understood. Here, we report the identification…”
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Post-Translational Regulation of ARF: Perspective in Cancer by Seo, Jinho, Seong, Daehyeon, Lee, Seung Ri, Oh, Doo-Byoung, Song, Jaewhan

“…Tumorigenesis can be induced by various stresses that cause aberrant DNA mutations and unhindered cell proliferation. Under such conditions, normal cells…”
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Engineering Ultrathin Alloy Shell in Au@AuPd Core‐Shell Nanoparticles for Efficient Plasmon‐Driven Photocatalysis by Kang, Eunbi, Seo, Jinho, Park, Hyewon, Wrasman, Cody J., Shin, Jae Won, Jo, Min‐kyun, Cargnello, Matteo, Park, Jeong Young, Lee, Hyosun

“…Bimetallic core‐shell nanoparticles (NPs) possessing a synergetic coupling of plasmonic and catalytic metals have emerged as promising prototypes for efficient…”
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The roles of FADD in extrinsic apoptosis and necroptosis by Lee, E.W., Yonsei University, Seoul, Republic of Korea, Seo, J.H., Yonsei University, Seoul, Republic of Korea, Jeong, M.H., Yonsei University, Seoul, Republic of Korea, Lee, S.S., Kwandong University, Gangneung, Republic of Korea, Song, J.W., Yonsei University, Seoul, Republic of Korea

“…Fas-associated protein with death domain (FADD), an adaptor that bridges death receptor signaling to the caspase cascade, is indispensible for the induction of…”
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Pericardial Recess: Computed Tomography Findings of Varying Disorders by Seo, Jinho, Kim, Youngtong, Jou, Sungshick, Park, Chanho

“…A pericardial recess is frequently seen in patients undergoing chest computed tomography (CT). It is important to be aware of the normal anatomy of the…”
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Antioxidants prevent particulate matter-induced senescence of lung fibroblasts by Jin, Sein, Yoon, Sung-Jin, Jung, Na-Young, Lee, Wang Sik, Jeong, Jinyoung, Park, Young-Jun, Kim, Wantae, Oh, Doo-Byoung, Seo, Jinho

“…Particulate matter (PM) contributes to human diseases, particularly lung disease; however, the molecular mechanism of its action is yet to be determined…”
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New role of E3 ubiquitin ligase in the regulation of necroptosis by Seo, Jinho, Lee, Eun-Woo, Song, Jaewhan

“…Necroptosis is a well-known form of caspase-independent cell death. Necroptosis can be triggered by various extrinsic stimuli, including death ligands in the…”
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BAP1 controls mesenchymal stem cell migration by inhibiting the ERK signaling pathway by Kim, Seobin, Lee, Eun-Woo, Oh, Doo-Byoung, Seo, Jinho

“…Due to their stem-like characteristics and immunosuppressive properties, Mesenchymal stem cells (MSCs) offer remarkable potential in regenerative medicine…”
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Structural and biochemical analyses of Bcl-xL in complex with the BH3 domain of peroxisomal testis-specific 1 by Lim, Dahwan, Jin, Sein, Shin, Ho-Chul, Kim, Wantae, Choi, Joon Sig, Oh, Doo-Byoung, Kim, Seung Jun, Seo, Jinho, Ku, Bonsu

“…Antiapoptotic B-cell lymphoma-2 (Bcl-2) proteins suppress apoptosis by interacting with proapoptotic regulators. They commonly contain a hydrophobic groove…”
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