Search Results - "Seo, Jeongyun"
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A microengineered pathophysiological model of early-stage breast cancer
Published in Lab on a chip (01-01-2015)“…A mounting body of evidence in cancer research suggests that the local microenvironment of tumor cells has a profound influence on cancer progression and…”
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Journal Article -
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Red blood cells induce necroptosis of lung endothelial cells and increase susceptibility to lung inflammation
Published in American journal of respiratory and critical care medicine (01-12-2014)“…Red blood cell (RBC) transfusions are associated with increased risk of acute respiratory distress syndrome (ARDS) in the critically ill, yet the mechanisms…”
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Journal Article -
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A microengineered model of RBC transfusion-induced pulmonary vascular injury
Published in Scientific reports (13-06-2017)“…Red blood cell (RBC) transfusion poses significant risks to critically ill patients by increasing their susceptibility to acute respiratory distress syndrome…”
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Journal Article -
4
Multiscale reverse engineering of the human ocular surface
Published in Nature medicine (01-08-2019)“…Here we present a miniaturized analog of a blinking human eye to reverse engineer the complexity of the interface between the ocular system and the external…”
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A Human Vascular Injury‐on‐a‐Chip Model of Hemostasis
Published in Small (Weinheim an der Bergstrasse, Germany) (01-04-2021)“…Hemostasis is an innate protective mechanism that plays a central role in maintaining the homeostasis of the vascular system during vascular injury. Studying…”
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Human Organ-On-Chips for the Study of Biomechanical Forces in Health and Disease
Published 01-01-2020“…The dynamically changing biomechanical environment in human organs plays a profound role in various cellular functions such as proliferation, three-dimensional…”
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Dissertation -
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Surface-directed engineering of tissue anisotropy in microphysiological models of musculoskeletal tissue
Published in Science advances (12-03-2021)“…Here, we present an approach to model and adapt the mechanical regulation of morphogenesis that uses contractile cells as sculptors of engineered tissue…”
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A bioinspired microfluidic model of liquid plug-induced mechanical airway injury
Published in Biomicrofluidics (01-07-2018)“…Occlusion of distal airways due to mucus plugs is a key pathological feature common to a wide variety of obstructive pulmonary diseases. Breathing-induced…”
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Journal Article