Search Results - "Seo, Jai"

The atypical mechanosensitive microRNA-712 derived from pre-ribosomal RNA induces endothelial inflammation and atherosclerosis by Son, Dong Ju, Kumar, Sandeep, Takabe, Wakako, Woo Kim, Chan, Ni, Chih-Wen, Alberts-Grill, Noah, Jang, In-Hwan, Kim, Sangok, Kim, Wankyu, Won Kang, Sang, Baker, Andrew H., Woong Seo, Jai, Ferrara, Katherine W., Jo, Hanjoong

“…MicroRNAs (miRNAs) regulate cardiovascular biology and disease, but the role of flow-sensitive microRNAs in atherosclerosis is still unclear. Here we identify…”
Get full text

In situ T-cell transfection by anti-CD3-conjugated lipid nanoparticles leads to T-cell activation, migration, and phenotypic shift by Kheirolomoom, Azadeh, Kare, Aris J., Ingham, Elizabeth S., Paulmurugan, Ramasamy, Robinson, Elise R., Baikoghli, Mo, Inayathullah, Mohammed, Seo, Jai W., Wang, James, Fite, Brett Z., Wu, Bo, Tumbale, Spencer K., Raie, Marina N., Cheng, R. Holland, Nichols, Lisa, Borowsky, Alexander D., Ferrara, Katherine W.

“…Ex vivo programming of T cells can be efficacious but is complex and expensive; therefore, the development of methods to transfect T cells in situ is…”
Get full text

The comparative efficacies of intra-articular and IV tranexamic acid for reducing blood loss during total knee arthroplasty by Seo, Jai-Gon, Moon, Young-Wan, Park, Sang-Hoon, Kim, Sang-Min, Ko, Kyung-Rae

“…Purpose Reduction in blood loss during surgery stabilizes hemodynamic status and aids in recovery after total knee arthroplasty (TKA). In this study, the…”
Get full text

Long-Circulating 15 nm Micelles Based on Amphiphilic 3-Helix Peptide–PEG Conjugates by Dong, He, Dube, Nikhil, Shu, Jessica Y, Seo, Jai W, Mahakian, Lisa M, Ferrara, Katherine W, Xu, Ting

“…Generating stable, multifunctional organic nanocarriers will have a significant impact on drug formulation. However, it remains a significant challenge to…”
Get full text

Multimodal imaging enables early detection and characterization of changes in tumor permeability of brain metastases by Thorsen, Frits, Fite, Brett, Mahakian, Lisa M., Seo, Jai W., Qin, Shengping, Harrison, Victoria, Johnson, Sarah, Ingham, Elizabeth, Caskey, Charles, Sundstrøm, Terje, Meade, Thomas J., Harter, Patrick N., Skaftnesmo, Kai Ove, Ferrara, Katherine W.

“…Our goal was to develop strategies to quantify the accumulation of model therapeutics in small brain metastases using multimodal imaging, in order to enhance…”
Get full text

Specific penetration and accumulation of a homing peptide within atherosclerotic plaques of apolipoprotein E-deficient mice by Hamzah, Juliana, Kotamraju, Venkata R, Seo, Jai W, Agemy, Lilach, Fogal, Valentina, Mahakian, Lisa M, Peters, David, Roth, Lise, Gagnon, M. Karen J, Ferrara, Katherine W, Ruoslahti, Erkki

“…The ability to selectively deliver compounds into atherosclerotic plaques would greatly benefit the detection and treatment of atherosclerotic disease. We…”
Get full text

Optimal rotational positioning of tibial component in total knee arthroplasty: determined by linker surgical technique using a high definition CT by Jung, Woon-Hwa, Seo, Jai-Gon, Kim, Dong Hyun, Balabadra, Suryamanikanta, Mandot, Utkrisht, Kumar, Dinesh

“…Introduction The rotational alignment of femoral and tibial components is an important determinant of the success of Total Knee Arthroplasty (TKA). The optimal…”
Get full text

Pre-clinical evaluation of immunoPET imaging using agonist CD40 monoclonal antibody in pancreatic tumor-bearing mice by Aghevlian, Sadaf, Wu, Bo, Raie, Marina Nura, Tumbale, Spencer K., Kare, Aris J., Seo, Jai W., Ferrara, Katherine W.

“…A novel [64Cu]Cu-NOTA-aCD40 immunoPET tracer was developed to image a CD40+ pancreatic tumor model in C57BL/6 mice and to study the biodistribution profile of…”
Get full text

Primary Total Knee Arthroplasty in Infection Sequelae About the Native Knee by Seo, Jai-Gon, MD, Moon, Young-Wan, MD, Park, Sang-Hoon, MD, Han, Kye-Young, MD, Kim, Sang-Min, MD

“…Abstract The aim of this study is to assess the results of primary total knee arthroplasty (TKA) after bone or joint sepsis about the native knee and to…”
Get full text

Outcomes of long retrograde intramedullary nailing for periprosthetic supracondylar femoral fractures following total knee arthroplasty by Lee, Sung-San, Lim, Seung-Jae, Moon, Young-Wan, Seo, Jai-Gon

“…Background The treatment of periprosthetic supracondylar femoral fractures following total knee arthroplasty (TKA) is challenging because of osteopenia and the…”
Get full text

Effect of Alkyl Length of Peptide–Polymer Amphiphile on Cargo Encapsulation Stability and Pharmacokinetics of 3‑Helix Micelles by Dube, Nikhil, Seo, Jai W, Dong, He, Shu, Jessica Y, Lund, Reidar, Mahakian, Lisa M, Ferrara, Katherine W, Xu, Ting

“…3-Helix micelles have demonstrated excellent in vitro and in vivo stability. Previous studies showed that the unique design of the peptide–polymer conjugate…”
Get full text

Ultrasound ablation enhances drug accumulation and survival in mammary carcinoma models by Wong, Andrew W, Fite, Brett Z, Liu, Yu, Kheirolomoom, Azadeh, Seo, Jai W, Watson, Katherine D, Mahakian, Lisa M, Tam, Sarah M, Zhang, Hua, Foiret, Josquin, Borowsky, Alexander D, Ferrara, Katherine W

“…Magnetic resonance-guided focused ultrasound (MRgFUS) facilitates noninvasive image-guided conformal thermal therapy of cancer. Yet in many scenarios, the…”
Get full text

Dynamic contrast enhanced MRI detects changes in vascular transport rate constants following treatment with thermally-sensitive liposomal doxorubicin by Fite, Brett Z., Kheirolomoom, Azadeh, Foiret, Josquin L., Seo, Jai W., Mahakian, Lisa M., Ingham, Elizabeth S., Tam, Sarah M., Borowsky, Alexander D., Curry, Fitz-Roy E., Ferrara, Katherine W.

“…Temperature-sensitive liposomal formulations of chemotherapeutics, such as doxorubicin, can achieve locally high drug concentrations within a tumor and tumor…”
Get full text

Erratum to: The comparative efficacies of intra-articular and IV tranexamic acid for reducing blood loss during total knee arthroplasty by Seo, Jai-Gon, Moon, Young-Wan, Park, Sang-Hoon, Kim, Sang-Min, Ko, Kyung-Rae

Get full text

Social and economic exchange in the employee-organization relationship: the moderating role of reciprocation wariness by Shore, Lynn M, Bommer, William H, Rao, Alaka N, Seo, Jai

“…Purpose - This paper examines the relationships that social and economic exchanges, two elements of the employee-organization relationship (EOR), had with…”
Get full text

Comparison of Cruciate Retaining and PCL Sacrificing TKA with Respect to Medial and Lateral Gap Differences in Varus Knees After Medial Release by Kim, Sang-Min, MD, PhD, Jang, Sung-Won, MD, Seo, Jai-Gon, MD, PhD, Lee, Sung-Sahn, MD, Moon, Young-Wan, MD, PhD

“…Abstract We aimed to clarify whether the increase in medial gap after medial release is influenced by the retention or sacrifice of posterior cruciate ligament…”
Get full text

UBR2 of the N-end rule pathway is required for chromosome stability via histone ubiquitylation in spermatocytes and somatic cells by An, Jee Young, Kim, Euna, Zakrzewska, Adriana, Yoo, Young Dong, Jang, Jun Min, Han, Dong Hoon, Lee, Min Jae, Seo, Jai Wha, Lee, Yong Jun, Kim, Tae-You, de Rooij, Dirk G, Kim, Bo Yeon, Kwon, Yong Tae

“…The N-end rule pathway is a proteolytic system in which its recognition components (N-recognins) recognize destabilizing N-terminal residues of short-lived…”
Get full text

Long-term follow-up and survivorship of single-radius, posterior-stabilized total knee arthroplasty by Chang, Moon Jong, So, Sangyeon, Park, Chan-Deok, Seo, Jai Gon, Moon, Young-Wan

“…We sought to determine the 10-year survivorship of single-radius, posterior-stabilized total knee arthroplasty (TKA) in Asian patients. We also aimed to…”
Get full text

Evaluation of Doxorubicin-Loaded 3‑Helix Micelles as Nanocarriers by Dube, Nikhil, Shu, Jessica Y, Dong, He, Seo, Jai W, Ingham, Elizabeth, Kheirolomoom, Azadeh, Chen, Pin-Yuan, Forsayeth, John, Bankiewicz, Krystof, Ferrara, Katherine W, Xu, Ting

“…Designing stable drug nanocarriers, 10–30 nm in size, would have significant impact on their transport in circulation, tumor penetration, and therapeutic…”
Get full text

Reconstruction of a deficient patella in revision total knee arthroplasty: results of a new surgical technique using transcortical wiring by Seo, Jai-Gon, Moon, Young-Wan, Lee, Byung-Hoon, Kim, Sang-Min

“…This study aimed to report the results of a novel surgical technique for the reconstruction of a deficient patella during revision total knee arthroplasty…”
Get full text