Search Results - "Seo, Hee Chan"
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Quantitative phosphoproteomic analysis reveals system-wide signaling pathways downstream of SDF-1/CXCR4 in breast cancer stem cells
Published in Proceedings of the National Academy of Sciences - PNAS (27-05-2014)“…Breast cancer is the leading cause of cancer-related mortality in women worldwide, with an estimated 1.7 million new cases and 522,000 deaths around the world…”
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Hox cluster disintegration with persistent anteroposterior order of expression in Oikopleura dioica
Published in Nature (02-09-2004)“…Tunicate embryos and larvae have small cell numbers and simple anatomical features in comparison with other chordates, including vertebrates. Although they…”
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SIX3 and SIX6 interact with GEMININ via C-terminal regions
Published in Biochemistry and biophysics reports (01-12-2019)“…The histoarchitecture and function of eye and forebrain depend on a well-controlled balance between cell proliferation and differentiation. For example, the…”
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The C-Terminal Domain of Eukaryotic Initiation Factor 5 Promotes Start Codon Recognition by Its Dynamic Interplay with eIF1 and eIF2β
Published in Cell reports (Cambridge) (28-06-2012)“…Recognition of the proper start codon on mRNAs is essential for protein synthesis, which requires scanning and involves eukaryotic initiation factors (eIFs)…”
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Differential Evolution of the 13 Atlantic Salmon Hox Clusters
Published in Molecular biology and evolution (01-07-2008)“…Hox cluster organization represents a valuable marker to study the effects of recent genome duplication in salmonid fish (25-100 Mya). Using polymerase chain…”
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Autoregulatory binding sites in the zebrafish six3a promoter region define a new recognition sequence for Six3 proteins
Published in The FEBS journal (01-04-2010)“…The homeodomain (HD) transcription factor Six3, which is a member of the Six/Sine oculis family, is essential for development of the eyes and forebrain in…”
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Isolation and characterization of two teleost melanopsin genes and their differential expression within the inner retina and brain
Published in Journal of comparative neurology (1911) (27-01-2003)“…Melanopsin is a newly discovered photopigment that is believed to be involved in the regulation of circadian rhythms in tetrapods. Here we describe the…”
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Spatio-temporal expression patterns of anterior Hox genes in Atlantic salmon ( Salmo salar)
Published in Gene Expression Patterns (01-09-2008)“…Hox genes encode transcription factors that play important roles in patterning the anterior–posterior (A–P) body axis. In vertebrates, up to 14 Hox genes are…”
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Identification of the neurotrophic factor sequence of prosaposin
Published in The FASEB journal (01-05-1995)“…Prosaposin, recently identified as a neurotrophic factor (1), is the precursor of saposins A, B, C, and D. The neurotrophic activity of prosaposin resides in…”
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Identification and distribution of nitric oxide synthase in the brain of adult zebrafish
Published in Neuroscience letters (06-10-2000)“…Nitric oxide (NO) is proposed to be involved in developmental and plastic processes. We investigated the presence and distribution of nitric oxide synthase…”
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RNA interference: mechanisms and applications
Published in Biotechnology Annual Review (2001)“…RNA interference (RNAi) is a phenomenon induced by double-stranded RNA (dsRNA) in which gene expression is inhibited through specific degradation of mRNA. The…”
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Book Chapter Journal Article -
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Involvement of Epidermal Growth Factor Receptor-Linked Signaling Responses in Pseudomonas fluorescens-Infected Alveolar Epithelial Cells
Published in Infection and Immunity (01-05-2011)“…Pseudomonas fluorescens is an opportunistic indoor pathogen that can cause severe airway proinflammatory responses. Pulmonary epithelium, like other mucosal…”
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Miniature Genome in the Marine Chordate Oikopleura dioica
Published in Science (American Association for the Advancement of Science) (21-12-2001)“…Oikopleura dioica is a small pelagic chordate belonging to the class of larvaceans. To obtain a view of overall genome organization, the authors randomly…”
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Remodelling of the homeobox gene complement in the tunicate Oikopleura dioica
Published in Current biology (11-01-2005)“…Homeodomain transcription factors are involved in many developmental processes [1] and have been intensely studied in a few model organisms, such as mouse,…”
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Six class homeobox genes in Drosophila belong to three distinct families and are involved in head development
Published in Mechanisms of development (01-05-1999)“…The vertebrate Six genes are homologues of the Drosophila homeobox gene sine oculis ( so), which is essential for development of the entire visual system. Here…”
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Hypervariable and highly divergent intron-exon organizations in the chordate Oikopleura dioica
Published in Journal of molecular evolution (01-10-2004)“…Oikopleura dioica is a pelagic tunicate with a very small genome and a very short life cycle. In order to investigate the intron-exon organizations in…”
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Retinal expression of zebrafish six3.1 and its regulation by Pax6
Published in Biochemical and biophysical research communications (19-09-2003)“…Homologues of the homeobox genes sine oculis ( so) and eyeless ( ey) are important regulators of eye development in both vertebrates and invertebrates. A…”
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Topography of different photoreceptor cell types in the larval retina of Atlantic halibut (Hippoglossus hippoglossus)
Published in Journal of experimental biology (15-07-2001)“…The identities of single cone cells in the retina of Atlantic halibut (Hippoglossus hippoglossus) larvae were studied by in situ hybridisation using RNA probes…”
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Identification of Prosaposin as a Neurotrophic Factor
Published in Proceedings of the National Academy of Sciences - PNAS (27-09-1994)“…Prosaposin was identified as a neurotrophic factor stimulating neurite outgrowth in murine neuroblastoma (NS20Y) cells and choline acetyltransferase (ChAT)…”
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The zebrafish Pax3 and Pax7 homologues are highly conserved, encode multiple isoforms and show dynamic segment-like expression in the developing brain
Published in Mechanisms of development (1998)“…This study describes the isolation and characterization of zebrafish homologues of the mammalian Pax3 and Pax7 genes. The proteins encoded by both zebrafish…”
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