Search Results - "Senyukov, Vladimir V"
-
1
Membrane-bound IL-21 promotes sustained ex vivo proliferation of human natural killer cells
Published in PloS one (18-01-2012)“…NK cells have therapeutic potential for a wide variety of human malignancies. However, because NK cells expand poorly in vitro, have limited life spans in…”
Get full text
Journal Article -
2
Off the shelf T cell therapies for hematologic malignancies
Published in Best practice & research. Clinical haematology (01-06-2018)“…Adoptive transfer of autologous CAR-T cells can induce durable remissions in patients with relapsed/refractory hematologic malignancies. However, multiple…”
Get full text
Journal Article -
3
Interferon Gamma Induces Changes in Natural Killer (NK) Cell Ligand Expression and Alters NK Cell-Mediated Lysis of Pediatric Cancer Cell Lines
Published in Frontiers in immunology (06-04-2017)“…Natural killer (NK) cells have therapeutic potential for cancer due to their capacity for targeting tumor cells without prior sensitization. Our laboratory has…”
Get full text
Journal Article -
4
Transcription of the activating receptor NKG2D in natural killer cells is regulated by STAT3 tyrosine phosphorylation
Published in Blood (17-07-2014)“…Signal transducer and activator of transcription 3 (STAT3) is considered a negative regulator of inflammation, as inhibition of STAT3 signaling enhances…”
Get full text
Journal Article -
5
Expansion, purification, and functional assessment of human peripheral blood NK cells
Published in Journal of visualized experiments (02-02-2011)“…Natural killer (NK) cells play an important role in immune surveillance against a variety of infectious microorganisms and tumors. Limited availability of NK…”
Get full text
Journal Article -
6
Erythroid cells in immunoregulation: characterization of a novel suppressor factor
Published in Immunology letters (15-05-2004)“…Nucleated erythroid cells (EC) have been previously reported to possess a potent natural suppressor (NS) activity for B-cell responses. In this study, we…”
Get full text
Journal Article -
7
KIR Ligation During Ex Vivo Expansion Allows Molding Of The KIR Repertoire
Published in Blood (15-11-2013)“…NK Cell subpopulations express tremendous diversity through polymorphisms, haplotypes, differential expression, and licensing of the Killer Immunoglobulin-like…”
Get full text
Journal Article -
8
Single-cell quantification of functional outcomes of CD16 ligation in NK cells by Fc-engineered antibodies
Published in Journal for immunotherapy of cancer (07-11-2013)Get full text
Journal Article -
9
Expansion, Purification, and Functional Assessment of Human Peripheral Blood NK Cells
Published in Journal of visualized experiments (02-02-2011)Get full text
Journal Article -
10
Tumor Growth Inhibitory and Natural Suppressor Activities of Murine Bone Marrow Cells: A Comparative Study
Published in Cellular immunology (25-11-1997)“…The murine bone marrow (BM) cells having a certain phenotypic similarity to null natural suppressor (NS) cells have been previously established to be able to…”
Get full text
Journal Article