Search Results - "Sentis, Stephanie"

Cracking the Estrogen Receptor's Posttranslational Code in Breast Tumors by Le Romancer, Muriel, Poulard, Coralie, Cohen, Pascale, Sentis, Stéphanie, Renoir, Jack-Michel, Corbo, Laura

“…Estrogen signaling pathways, because of their central role in regulating the growth and survival of breast tumor cells, have been identified as suitable and…”
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Role of PRMT1 and PRMT5 in Breast Cancer by Martinez, Sébastien, Sentis, Stéphanie, Poulard, Coralie, Trédan, Olivier, Le Romancer, Muriel

“…Breast cancer is the most common cancer diagnosed in women worldwide. Early-stage breast cancer is curable in ~70-80% of patients, while advanced metastatic…”
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Regulation of Estrogen Rapid Signaling through Arginine Methylation by PRMT1 by Le Romancer, Muriel, Treilleux, Isabelle, Leconte, Nicolas, Robin-Lespinasse, Yannis, Sentis, Stéphanie, Bouchekioua-Bouzaghou, Katia, Goddard, Sophie, Gobert-Gosse, Stéphanie, Corbo, Laura

“…Evidence is emerging that estrogen receptor α (ERα) is central to the rapid transduction of estrogen signaling to the downstream kinase cascades; however, the…”
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Schwann cells support oncogenic potential of pancreatic cancer cells through TGFβ signaling by Roger, Elodie, Martel, Sylvie, Bertrand-Chapel, Adrien, Depollier, Arnaud, Chuvin, Nicolas, Pommier, Roxane M., Yacoub, Karam, Caligaris, Cassandre, Cardot-Ruffino, Victoire, Chauvet, Véronique, Aires, Sophie, Mohkam, Kayvan, Mabrut, Jean-Yves, Adham, Mustapha, Fenouil, Tanguy, Hervieu, Valérie, Broutier, Laura, Castets, Marie, Neuzillet, Cindy, Cassier, Philippe A., Tomasini, Richard, Sentis, Stéphanie, Bartholin, Laurent

“…Pancreatic ductal adenocarcinoma (PDAC) is one of the solid tumors with the poorest prognosis. The stroma of this tumor is abundant and composed of…”
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Tenascin-X promotes epithelial-to-mesenchymal transition by activating latent TGF-β by Alcaraz, Lindsay B, Exposito, Jean-Yves, Chuvin, Nicolas, Pommier, Roxane M, Cluzel, Caroline, Martel, Sylvie, Sentis, Stéphanie, Bartholin, Laurent, Lethias, Claire, Valcourt, Ulrich

“…Transforming growth factor β (TGF-β) isoforms are secreted as inactive complexes formed through noncovalent interactions between the bioactive TGF-β entity and…”
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SMAD2/3 mediate oncogenic effects of TGF-β in the absence of SMAD4 by Bertrand-Chapel, Adrien, Caligaris, Cassandre, Fenouil, Tanguy, Savary, Clara, Aires, Sophie, Martel, Sylvie, Huchedé, Paul, Chassot, Christelle, Chauvet, Véronique, Cardot-Ruffino, Victoire, Morel, Anne-Pierre, Subtil, Fabien, Mohkam, Kayvan, Mabrut, Jean-Yves, Tonon, Laurie, Viari, Alain, Cassier, Philippe, Hervieu, Valérie, Castets, Marie, Mauviel, Alain, Sentis, Stéphanie, Bartholin, Laurent

“…TGF-β signaling is involved in pancreatic ductal adenocarcinoma (PDAC) tumorigenesis, representing one of the four major pathways genetically altered in 100%…”
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Generation of a conditional Flpo/FRT mouse model expressing constitutively active TGFβ in fibroblasts by Cardot-Ruffino, Victoire, Chauvet, Véronique, Caligaris, Cassandre, Bertrand-Chapel, Adrien, Chuvin, Nicolas, Pommier, Roxane M., Valcourt, Ulrich, Vincent, David F., Martel, Sylvie, Aires, Sophie, Kaniewski, Bastien, Dubus, Pierre, Cassier, Philippe, Sentis, Stéphanie, Bartholin, Laurent

“…Transforming growth factor (TGFβ) is a secreted factor, which accumulates in tissues during many physio- and pathological processes such as embryonic…”
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Transcriptional Repression of Estrogen Receptor α Signaling by SENP2 in Breast Cancer Cells by Nait Achour, Thiziri, Sentis, Stéphanie, Teyssier, Catherine, Philippat, Amandine, Lucas, Annick, Corbo, Laura, Cavaillès, Vincent, Jalaguier, Stéphan

“…Estrogen receptors (ERs) are ligand-activated transcription factors involved in many physiological and pathological processes, including breast cancer. Their…”
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TIF1γ Suppresses Tumor Progression by Regulating Mitotic Checkpoints and Chromosomal Stability by Pommier, Roxane M, Gout, Johann, Vincent, David F, Alcaraz, Lindsay B, Chuvin, Nicolas, Arfi, Vanessa, Martel, Sylvie, Kaniewski, Bastien, Devailly, Guillaume, Fourel, Geneviève, Bernard, Pascal, Moyret-Lalle, Caroline, Ansieau, Stéphane, Puisieux, Alain, Valcourt, Ulrich, Sentis, Stéphanie, Bartholin, Laurent

“…The transcription accessory factor TIF1γ/TRIM33/RFG7/PTC7/Ectodermin functions as a tumor suppressor that promotes development and cellular differentiation…”
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Generation of an Fsp1 (fibroblast‐specific protein 1)‐Flpo transgenic mouse strain by Cardot‐Ruffino, Victoire, Chauvet, Véronique, Caligaris, Cassandre, Bertrand‐Chapel, Adrien, Chuvin, Nicolas, Pommier, Roxane M., Valcourt, Ulrich, Vincent, David, Martel, Sylvie, Aires, Sophie, Kaniewski, Bastien, Dubus, Pierre, Cassier, Philippe, Sentis, Stéphanie, Bartholin, Laurent

“…Summary Recombination systems represent a major breakthrough in the field of genetic model engineering. The Flp recombinases (Flp, Flpe, and Flpo) bind and…”
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hCAF1, a new regulator of PRMT1-dependent arginine methylation by Robin-Lespinasse, Yannis, Sentis, Stéphanie, Kolytcheff, Chloé, Rostan, Marie-Claude, Corbo, Laura, Le Romancer, Muriel

“…Protein arginine methylation is an emergent post-translational modification involved in a growing number of cellular processes, including transcriptional…”
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hCAF1/CNOT7 regulates interferon signalling by targeting STAT1 by Chapat, Clément, Kolytcheff, Chloé, Le Romancer, Muriel, Auboeuf, Didier, De La Grange, Pierre, Chettab, Kamel, Sentis, Stéphanie, Corbo, Laura

“…Stringent regulation of the interferon (IFN) signalling pathway is essential for maintaining the immune response to pathogens and tumours. The transcription…”
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Protein arginine methylation in estrogen signaling and estrogen-related cancers by Teyssier, Catherine, Le Romancer, Muriel, Sentis, Stéphanie, Jalaguier, Stéphan, Corbo, Laura, Cavaillès, Vincent

“…Estrogen signaling pathways regulate multiple cellular processes including proliferation and differentiation, and dysregulation of these pathways underlies…”
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Conservation of the deadenylase activity of proteins of the Caf1 family in human by Bianchin, Claire, Mauxion, Fabienne, Sentis, Stéphanie, Séraphin, Bertrand, Corbo, Laura

“…The yeast Pop2 protein, belonging to the eukaryotic Caf1 family, is required for mRNA deadenylation in vivo. It also catalyzes poly(A) degradation in vitro,…”
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Correction: Schwann cells support oncogenic potential of pancreatic cancer cells through TGFβ signaling by Roger, Elodie, Martel, Sylvie, Bertrand-Chapel, Adrien, Depollier, Arnaud, Chuvin, Nicolas, Pommier, Roxane M., Yacoub, Karam, Caligaris, Cassandre, Cardot-Ruffino, Victoire, Chauvet, Véronique, Aires, Sophie, Mohkam, Kayvan, Mabrut, Jean-Yves, Adham, Mustapha, Fenouil, Tanguy, Hervieu, Valérie, Broutier, Laura, Castets, Marie, Neuzillet, Cindy, Cassier, Philippe A., Tomasini, Richard, Sentis, Stéphanie, Bartholin, Laurent

“…The original version of this article contained an error in the name of one of the co-authors (Kayvan Mohkam). This has been corrected in the PDF and HTML…”
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A Particular DNA Structure is Required for the Function of a Cis-Acting Component of the Epstein-Barr Virus OriLyt Origin of Replication by Portes-Sentis, Stephanie, Sergeant, Alain, Gruffat, Henri

“…OriLyt, the cis-acting element of Epstein-Barr virus lytic origin of replication, consists of upstream and downstream components. The upstream component plays…”
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Sumoylation of the Estrogen Receptor α Hinge Region Regulates Its Transcriptional Activity by Sentis, Stephanie, Le Romancer, Murielle, Bianchin, Claire, Rostan, Marie-Claude, Corbo, Laura

“…The steroid hormone 17β-estradiol (estrogen) plays a significant role in the normal physiology of the mammary gland and breast cancer development primarily…”
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BTG2 antiproliferative protein interacts with the human CCR4 complex existing in vivo in three cell-cycle-regulated forms by Morel, Anne-Pierre, Sentis, Stéphanie, Bianchin, Claire, Le Romancer, Muriel, Jonard, Laurence, Rostan, Marie-Claude, Rimokh, Ruth, Corbo, Laura

“…The yeast CCR4-NOT complex exists in two forms (1.0 and 1.9 MDa) that share several common subunits, including yCCR4, yCAF1 and five NOT proteins (NOT1-5)…”
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Acinar-to-Ductal Metaplasia Induced by Transforming Growth Factor Beta Facilitates KRAS G12D -driven Pancreatic Tumorigenesis by Chuvin, Nicolas, Vincent, David F, Pommier, Roxane M, Alcaraz, Lindsay B, Gout, Johann, Caligaris, Cassandre, Yacoub, Karam, Cardot, Victoire, Roger, Elodie, Kaniewski, Bastien, Martel, Sylvie, Cintas, Celia, Goddard-Léon, Sophie, Colombe, Amélie, Valantin, Julie, Gadot, Nicolas, Servoz, Emilie, Morton, Jennifer, Goddard, Isabelle, Couvelard, Anne, Rebours, Vinciane, Guillermet, Julie, Sansom, Owen J, Treilleux, Isabelle, Valcourt, Ulrich, Sentis, Stéphanie, Dubus, Pierre, Bartholin, Laurent

“…Transforming growth factor beta (TGFβ) acts either as a tumor suppressor or as an oncogene, depending on the cellular context and time of activation. TGFβ…”
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Post-translational modifications modulate estrogen receptor alpha activity in breast tumors by Poulard, Coralie, Bouchekioua-Bouzaghou, Katia, Sentis, Stéphanie, Corbo, Laura, Le Romancer, Muriel

“…Regulation of the proteome by post-translational modifications (PTM) emerges as a major contributing factor to the functional diversity in biology regulating…”
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