Search Results - "Senoh, Hachiro"

Studies on Anti-inflammatory Agents. IV. Synthesis and Pharmacological Properties of 1, 5-Diarylpyrazoles and Related Derivatives by TSUJI, Kiyoshi, NAKAMURA, Katsuya, KONISHI, Nobukiyo, TOJO, Takashi, OCHI, Takehiro, SENOH, Hachiro, MATSUO, Masaaki

“…A series of novel 1, 5-diarylpyrazole derivatives was synthesized and tested for anti-inflammatory and analgesic activities to develop anti-inflammatory agents…”
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Studies on Anti-inflammatory Agents. V. Synthesis and Pharmacological Properties of 3-(Difluoromethyl)-1-(4-methoxyphenyl)-5-(4-(methylsulfinyl)phenyl)pyrazole and Related Compounds by TSUJI, Kiyoshi, KONISHI, Nobukiyo, SPEARS, Glen W., OGINO, Takashi, NAKAMURA, Katsuya, TOJO, Takashi, OCHI, Takehiro, SHIMOJO, Fumio, SENOH, Hachiro, MATSUO, Masaaki

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T cell activation-associated hepatic injury : mediation by tumor necrosis factors and protection by interleukin 6 by MIZUHARA, H, O'NEILL, E, SEKI, N, OGAWA, T, KUSUNOKI, C, OTSUKA, K, SATOH, S, NIWA, M, SENOH, H, FUJIWARA, H

“…This study investigates the molecular mechanisms underlying the induction of and protection from T cell activation-associated hepatic injury. When BALB/c mice…”
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Critical involvement of interferon gamma in the pathogenesis of T-cell activation-associated hepatitis and regulatory mechanisms of interleukin-6 for the manifestations of hepatitis by Mizuhara, H, Uno, M, Seki, N, Yamashita, M, Yamaoka, M, Ogawa, T, Kaneda, K, Fujii, T, Senoh, H, Fujiwara, H

“…A single intravenous injection of concanavalin A (Con A) induces T-cell activation and an acute hepatitis in mice. This study investigated the role of…”
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Anti-inflammatory and analgesic effects of FK3311, a selective inhibitor of cyclooxygenase in inflamed tissues by Ochi, Takehiro, Senoh, Hachiro

“…FK3311 (4'acetyl-2'-「2, 4-difluorophenoxy」 methanesulfonanilide), is a neutral non-steroidal anti-inflammatory compound with improved gastrointestinal…”
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The pharmacological profiles of novel tachykinin antagonists, FR 113680 and FK 224 by Senoh, Hachiro, Morimoto, Hiroshi

“…We have discovered novel substance P (SP) antagonists, FR 113680 「N^α -「N^α -(N^α -acetyl-L-threonyl)-N^in…”
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Effects of novel tachykinin antagonists, FR 113680 and FK 224, on cigarette smoke-induced rat tracheal plasma extravasation by Morimoto, Hiroshi, Senoh, Hachiro

“…We examined the effects of novel tachykinin antagonists, FR 113680 and FK 224, on rat tracheal plasma extravasation induced by cigarette smoke. Intravenous…”
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The participation of arachidonic acid metabolites in cargeenan-induced inflammation and hyperalgesia by Ochi, Takehiro, Senoh, Hachiro

“…We studied the role of arachidonic acid metabolites in cargeenan-induced edama and hyperalgesia. Injection of cargeenan into the rat paws resulted in edema and…”
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The participation of arachidonate metabolites in yeast-induced hyperalgesia and edema by Ochi, Takehiro, Senoh, Hachiro

“…We studied the role of arachidonate metabolites in yeast-induced hyperalgesia and edema. Injection of brewer's yeast into the rat paw results in edema and…”
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Antiplatelet activities of FK409. a new spontaneous nitric oxide releaser by Hirasawa, Yoshimi, Maeda, Kazuhiro, Senoh, Hachiro, Yoshida, Keizo, Kita, Yasuhiro

“…FK409 is a new spontaneous nitric oxide (NO) releaser. In this study, we investigated the in vitro and in vivo antiplatelet effects of FK409 in rats, compared…”
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Plasma Extravasation by Chemical Mediators in Rat Skin and Trachea: A Role of Neurogenic Agents on Tracheal Edema Formation by MORIMOTO, Hiroshi, FUJII, Takashi, SENOH, Hachiro

“…The plasma extravasation inducing activities of several chemical mediators (allergic agents: histamine, leukotriene C4 (LTC4) and platelet activating factor…”
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Strain difference in the induction of T‐cell activation–associated, interferon gamma–dependent hepatic injury in mice by Mizuhara, Hidekazu, Kuno, Masako, Seki, Nobuo, Yu, Wen‐Gong, Yamaoka, Makiko, Yamashita, Masakatsu, Ogawa, Toshikazu, Kaneda, Kenji, Fujii, Takashi, Senoh, Hachiro, Fujiwara, Hiromi

“…A single intravenous injection of concanavalin A (Con A) induces T‐cell activation–associated inflammatory injury selectively in the liver. This study…”
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The antiinflammatory effect of budesonide ointment and cream by Hiroi, J, Fujii, T, Satoh, S, Yoneda, K, Senoh, H, Mori, J, Kikuchi, H

“…The antiinflammatory effect of topically applied budesonide ointment on carrageenin induced paw edema in rats, croton oil induced ear edema in rats, passive…”
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The participation of arachidonate metabolites in type II collagen-induced arthritis in mice by Ochi, Takehiro, Mizuhara, Hidekazu, Seki, Nobuo, Morimoto, Hiroshi, Imazumi, Katsunori, Matsuda, Atsushi, Yamashita, Masakatsu, Fujii, Takashi, Senoh, Hachiro

“…We studied the role of arachidonic acid cascade in type II collagen-induced arthritis in DBA/1 mice. The mice were immunized with 0.1 mg bovine type II…”
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Host mediated anti-tumor effect of Nocardia rubra cell wall skeleton on syngeneic tumor in mice by Hirai, O, Fujitsu, T, Oku, R, Satoh, H, Shimomura, K, Ennyu, K, Senoh, H, Mori, J, Kikuchi, H

“…The mode of action of Nocardia rubra cell wall skeleton (N-CWS) on Meth A fibrosarcoma (Meth A) was studied in BALB/c mice. N-CWS suppressed or regressed the…”
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The anti-inflammatory effect of auranofin by Hiroi, J, Ohara, K, Fujitsu, T, Hirai, O, Satoh, S, Ochi, T, Senoh, H, Mori, J, Kikuchi, H

“…The anti-inflammatory effects of auranofin were studied and compared with those of indomethacin, gold sodium thiomalate (GST) and D-penicillamine. Auranofin…”
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The antiinflammatory effect of budesonide by Hiroi, J, Fujii, T, Satoh, S, Ochi, T, Kobayashi, K, Ohyanagi, Y, Senoh, H, Mori, J, Kikuchi, H

“…The systemic and topical antiinflammatory activities of budesonide (B) were studied in rats and mice and compared with those of commercially available…”
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Clinical benefits and tolerability of increased fill volumes in Japanese peritoneal dialysis patients by Fukatsu, A, Komatsu, Y, Senoh, H, Miyai, H, Tanaka, Y, Oiwa, T, Nakauchi, M, Kasori, R, Takahashi, S, Kawahara, H, Mayber, N, Yost, LE, Ogrinc, FG, Mujais, S

“…Division of Artificial Kidneys, Kyoto University Hospital, Japan. afukatsu@kuhp.kyoto-u.ac.jp…”
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Antianginal effects of FK409, a new spontaneous NO releaser by Kita, Yasuhiro, Ozaki, Reiko, Sakai, Shigeru, Sugimoto, Toshiko, Hirasawa, Yoshimi, Ohtsuka, Minoru, Senoh, Hachiro, Yoshida, Keizo, Maeda, Kazuhiro

“…1 The aim of this study was to compare antianginal effects of (±)‐(E)‐ethyl‐2‐[(E)‐hydroxyimino]‐5‐nitro‐3‐hexeneamide (FK409), a new spontaneous nitric oxide…”
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DISTURBANCE OF IMMUNE SYSTEM IN MICE BY ADMINISTRATION OF 7, 12-DIMETHYLBENZ[a]ANTHRACENE AND NORMAL THYMOCYTES by MATSUOKA, Yuji, FUJIWARA, Hiromi, SENOH, Hachiro, KITAGAWA, Masayasu

“…Mice given 7, 12-dimethylbenz[a]anthracene (DMBA) simultaneously with immunization with bacterial α-amylase (BαA) showed an augmented anti-BαA response in sera…”
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