Search Results - "Sennitt, Matthew"

Effect of high-fat diet on the expression of proteins in muscle, adipose tissues, and liver of C57BL/6 mice by Schmid, Gerhard M., Converset, Véronique, Walter, Nadia, Sennitt, Matthew V., Leung, Kit-Yi, Byers, Helen, Ward, Malcolm, Hochstrasser, Denis F., Cawthorne, Michael A., Sanchez, Jean-Charles

“…In the present study, the effect of a high fat diet on the expression of proteins in insulin target tissues was analyzed using a proteomic approach…”
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Prolonged treatment of genetically obese mice with conjugated linoleic acid improves glucose tolerance and lowers plasma insulin concentration: possible involvement of PPAR activation by Wargent, Ed, Sennitt, Matthew V, Stocker, Claire, Mayes, Andrew E, Brown, Louise, O'Dowd, Jacqueline, Wang, Steven, Einerhand, Alexandra W C, Mohede, Inge, Arch, Jonathan R S, Cawthorne, Michael A

“…Studies in rodents and some studies in humans have shown that conjugated linoleic acid (CLA), especially its trans-10, cis-12 isomer, reduces body fat content…”
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Effect of Rosiglitazone on the Differential Expression of Diabetes-associated Proteins in Pancreatic Islets of C57Bl/6 lep/lep Mice by Sanchez, Jean-Charles, Converset, Véronique, Nolan, Anna, Schmid, Gerhard, Wang, Steven, Heller, Manfred, Sennitt, Matthew V, Hochstrasser, Denis F, Cawthorne, Michael A

“…The insulin sensitizer drug, rosiglitazone, has been shown to have a protective effect on pancreatic islet cell structure and function in animal models of type…”
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The mouse SWISS-2D PAGE database: a tool for proteomics study of diabetes and obesity by Sanchez, Jean-Charles, Chiappe, Diego, Converset, Véronique, Hoogland, Christine, Binz, Pierre-Alain, Paesano, Salvo, Appel, Ron D., Wang, Steven, Sennitt, Matthew, Nolan, Anna, Cawthorne, Michael A., Hochstrasser, Denis F.

“…A number of two‐dimensional electrophoresis (2‐DE) reference maps from mouse samples have been established and could be accessed through the internet. An…”
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Effect of rosiglitazone on the differential expression of obesity and insulin resistance associated proteins in lep/lep mice by Sanchez, Jean-Charles, Converset, Véronique, Nolan, Anna, Schmid, Gerhard, Wang, Steven, Heller, Manfred, Sennitt, Matthew V., Hochstrasser, Denis F., Cawthorne, Michael A.

“…Peroxisome proliferator‐activated receptors (PPARs) participate in the molecular mechanism of pathologies with altered lipid homeostasis such as type 2…”
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The effects of rexinoids and rosiglitazone on body weight and uncoupling protein isoform expression in the Zucker fa/fa rat by Emilsson, Valur, O'Dowd, Jacqueline, Wang, Steven, Liu, Yong-Ling, Sennitt, Matthew, Heyman, Richard, Cawthorne, Michael A.

“…Agonists for the retinoid X receptor (RXR), the rexinoids, and the peroxisome proliferator-activated receptor gamma (PPAR γ), the thiazolidinediones, are…”
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Antihyperglycemic Effects of Novel Long- and Short-Acting Glucokinase Activators (PSN105 and PSN010) in Diabetic Animals by Fyfe, Matthew C T, Cawthorne, Michael A, Sennitt, Matthew V, Printz, Richard L

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Effect of Rosiglitazone on the Differential Expression of Diabetes Associated Proteins in Pancreatic Islets of C57B1/6J lep/lep Mice by SANCHEZ, JEAN-CHARLES, ROUGE, VERONIQUE, HOCHSTRASSER, DENIS, SENNITT, MATTHEW V, WANG, STEVEN, PALLETT, ANNA A, CAWTHORNE, MICHAEL A

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BRL 35135, a potent and selective atypical β-adrenoceptor agonist by Cawthorne, MA, Sennitt, MV, Arch, JR, Smith, SA

“…BRL 35135, via its active deesterified metabolite BRL 37344, is a potent example of a new group of β-adrenoceptor agonists that stimulate selectively a novel β…”
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The selectivity in vitro of the stereoisomers of the beta-3 adrenoceptor agonist BRL 37344 by Oriowo, M A, Chapman, H, Kirkham, D M, Sennitt, M V, Ruffolo, Jr, R R, Cawthorne, M A

“…The stimulation by BRL 37344 of lipolysis in rat adipose tissues, and of relaxation of the rat distal colon, is mediated by the beta-3 adrenoceptor. The…”
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The rat lipolytic beta-adrenoceptor: studies using novel beta-adrenoceptor agonists by Wilson, C, Wilson, S, Piercy, V, Sennitt, M V, Arch, J R

“…EC50 and relative intrinsic activity values were obtained for isoprenaline, fenoterol, salbutamol, prenalterol and three new beta-adrenoceptor agonists, BRL…”
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Anti-hyperglycaemic action of BRL 26830, a novel beta-adrenoceptor agonist, in mice and rats by Sennitt, M V, Arch, J R, Levy, A L, Simson, D L, Smith, S A, Cawthorne, M A

“…BRL 26830, (R*,R*)-(+/-)-methyl 4-[2-[(2-hydroxy-2-phenylethyl)amino] propyl] benzoate, is a new orally active anti-hyperglycaemic agent. In 24 hr-fasted rats…”
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Effects of BRL 26830, a novel beta-adrenoceptor agonist, on glucose tolerance, insulin sensitivity and glucose turnover in Zucker (fa/fa) rats by Smith, S A, Levy, A L, Sennitt, M V, Simson, D L, Cawthorne, M A

“…Zucker fa/fa rats exhibit glucose intolerance in comparison with lean Fa/? littermates. A single acute dose of BRL 26830 (2.9 mg/kg p.o.) improved glucose…”
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Effect of a novel thermogenic beta-adrenoceptor agonist (BRL 26830) on insulin resistance in soleus muscle from obese Zucker rats by Challiss, R A, Budohoski, L, Newsholme, E A, Sennitt, M V, Cawthorne, M A

“…Young lean (Fa/?) and obese (fa/fa) rats were treated with the thermogenic beta-adrenoceptor agonist, BRL 26830, for 3 weeks. In lean rats this treatment had…”
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