Search Results - "Senneff, Thomas C."
-
1
Site-specific effects of neurosteroids on GABAA receptor activation and desensitization
Published in eLife (21-09-2020)“…This study examines how site-specific binding to three identified neurosteroid-binding sites in the α 1 β 3 GABA A receptor (GABA A R) contributes to…”
Get full text
Journal Article -
2
Steady‐state activation and modulation of the synaptic‐type α1β2γ2L GABAA receptor by combinations of physiological and clinical ligands
Published in Physiological reports (01-09-2019)“…The synaptic α1β2γ2 GABAA receptor is activated phasically by presynaptically released GABA. The receptor is considered to be inactive between synaptic events…”
Get full text
Journal Article -
3
Steady-state activation of the high-affinity isoform of the α4β2δ GABAA receptor
Published in Scientific reports (05-11-2019)“…Activation of GABA A receptors consisting of α4, β2 (or β3), and δ subunits is a major contributor to tonic inhibition in several brain regions. The goal of…”
Get full text
Journal Article -
4
Site-specific effects of neurosteroids on GABA A receptor activation and desensitization
Published in eLife (21-09-2020)“…This study examines how site-specific binding to three identified neurosteroid-binding sites in the α β GABA receptor (GABA R) contributes to neurosteroid…”
Get full text
Journal Article -
5
Steady‐state activation and modulation of the synaptic‐type α 1 β 2 γ 2L GABA A receptor by combinations of physiological and clinical ligands
Published in Physiological reports (01-09-2019)“…The synaptic α1β2γ2 GABAA receptor is activated phasically by presynaptically released GABA. The receptor is considered to be inactive between synaptic events…”
Get full text
Journal Article -
6
Site-specific effects of neurosteroids on GABA.sub.A receptor activation and desensitization
Published in eLife (21-09-2020)“…This study examines how site-specific binding to three identified neurosteroid-binding sites in the [alpha].sub.1[beta].sub.3 GABA.sub.A receptor (GABA.sub.AR)…”
Get full text
Journal Article -
7
Steady-state activation of the high-affinity isoform of the α4β2δ GABA A receptor
Published in Scientific reports (05-11-2019)“…Activation of GABA receptors consisting of α4, β2 (or β3), and δ subunits is a major contributor to tonic inhibition in several brain regions. The goal of this…”
Get full text
Journal Article -
8
Steady-state activation and modulation of the synaptic-type α1β2γ2L GABA A receptor by combinations of physiological and clinical ligands
Published in Physiological reports (01-09-2019)“…The synaptic α1β2γ2 GABA receptor is activated phasically by presynaptically released GABA. The receptor is considered to be inactive between synaptic events…”
Get full text
Journal Article