Search Results - "Senior, Aaron J"

Iodoetherification as a strategy towards sp3-rich scaffolds for drug discovery by Barnes, Lydia, Birkinshaw, Timothy N., Senior, Aaron J., Brügge, Oscar Siles, Lewis, William, Argent, Stephen P., Moody, Christopher J., Nortcliffe, Andrew

“…[Display omitted] Functionalised tetrahydropyran and spirooxepane scaffolds were prepared utilising an iodoetherification strategy and elaborated to…”
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Iodoetherification as a strategy towards sp 3 -rich scaffolds for drug discovery by Barnes, Lydia, Birkinshaw, Timothy N, Senior, Aaron J, Brügge, Oscar Siles, Lewis, William, Argent, Stephen P, Moody, Christopher J, Nortcliffe, Andrew

“…Functionalised tetrahydropyran and spirooxepane scaffolds were prepared utilising an iodoetherification strategy and elaborated to demonstrate their potential…”
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Free–Wilson Analysis of Comprehensive Data on Phosphoinositide-3-kinase (PI3K) Inhibitors Reveals Importance of N‑Methylation for PI3Kδ Activity by Barnes, Lydia, Blaber, Hollie, Brooks, David T. K, Byers, Lewis, Buckley, Daniel, Byron, Zoe C, Chilvers, Richard G, Cochrane, Liam, Cooney, Edward, Damian, Heather A, Francis, Luke, Fu He, Daniel, Grace, Jack M. J, Green, Harley J, Hogarth, Edmund J. P, Jusu, Leyla, Killalea, C. Elizabeth, King, Oliver, Lambert, Joseph, Lee, Zoe J, Lima, Nuria S, Long, Christina L, Mackinnon, May-Li, Mahdy, Shusha, Matthews-Wright, Jolyon, Millward, Makenzie J, Meehan, Matthew F, Merrett, Christopher, Morrison, Lisa, Parke, Hal R. I, Payne, Charlotte, Payne, Lawrence, Pike, Craig, Seal, Alexander, Senior, Aaron J, Smith, Keenan M, Stanelyte, Kamile, Stillibrand, Joe, Szpara, Rachel, Taday, Freya F. H, Threadgould, Antony M, Trainor, Rohan J, Waters, Jordan, Williams, Oliver, Wong, Carrie K. W, Wood, Katherine, Barton, Nick, Gruszka, Anna, Henley, Zoe, Rowedder, James E, Cookson, Rosa, Jones, Katherine L, Nadin, Alan, Smith, Ian E, Macdonald, Simon J. F, Nortcliffe, Andrew

“…Phosphoinositide-3-kinase δ (PI3Kδ) is a critical regulator of cell growth and transformation and has been explored as a therapeutic target for a range of…”
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