Search Results - "Sengupta, J. N."

The role of transient receptor potential vanilloid 1 in mechanical and chemical visceral hyperalgesia following experimental colitis by Miranda, A, Nordstrom, E, Mannem, A, Smith, C, Banerjee, B, Sengupta, J.N

“…Abstract The transient receptor potential vanilloid 1 receptor (TRPV1) is an important nociceptor involved in neurogenic inflammation. We aimed to examine the…”
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Biphasic Modulation of Spinal Visceral Nociceptive Transmission From the Rostroventral Medial Medulla in the Rat by Zhuo, M, Sengupta, J. N, Gebhart, G. F

“…Department of Pharmacology, College of Medicine, The University of Iowa, Iowa City, Iowa 52242 Zhuo, M., J. N. Sengupta, and G. F. Gebhart. Biphasic Modulation…”
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Differential effects of transient receptor vanilloid one (TRPV1) antagonists in acid-induced excitation of esophageal vagal afferent fibers of rats by Peles, S, Medda, B.K, Zhang, Zhihong, Banerjee, B, Lehmann, A, Shaker, R, Sengupta, J.N

“…Abstract Gastro-esophageal acid reflux can stimulate esophageal vagal sensory afferents by activating proton-sensitive ion channel transient receptor vanilloid…”
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Effects of kappa opioids in the inflamed rat colon by Sengupta, J N, Snider, A, Su, X, Gebhart, G F

“…The objective of this study was to examine the antinociceptive effects of peripherally restricted kappa-opioid receptor agonists (ORAs) in a rat model of…”
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Neonatal cystitis‐induced colonic hypersensitivity in adult rats: a model of viscero‐visceral convergence by Miranda, A., Mickle, A., Schmidt, J., Zhang, Z., Shaker, R., Banerjee, B., Sengupta, J. N.

“…Background  The objective of this study was to determine if neonatal cystitis alters colonic sensitivity later in life and to investigate the role of…”
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Models of gastric hyperalgesia in the rat by Ozaki, Noriyuki, Bielefeldt, Klaus, Sengupta, J N, Gebhart, G F

“…Despite the prevalence of dyspepsia, nonhuman models for study of gastric hyperalgesia are limited. We thus characterized responses to gastric distension (GD)…”
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Mechanosensitive Properties of Gastric Vagal Afferent Fibers in the Rat by Ozaki, Noriyuki, Sengupta, J. N, Gebhart, G. F

“…Department of Pharmacology, College of Medicine, University of Iowa, Iowa City, Iowa 52242 Ozaki, Noriyuki, J. N. Sengupta, and G. F. Gebhart. Mechanosensitive…”
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Mechanosensitive properties of pelvic nerve afferent fibers innervating the urinary bladder of the rat by Sengupta, J N, Gebhart, G F

“…1. Single-unit activity was recorded from S1 dorsal root afferent fibers in pentobarbital-anesthetized rats. In 25 experiments, 245 afferent fibers were…”
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Characterization of mechanosensitive pelvic nerve afferent fibers innervating the colon of the rat by Sengupta, J N, Gebhart, G F

“…1. Single-unit activity was recorded from S1 sacral dorsal root afferent fibers in the anesthetized rat. A total of 364 afferent fibers were identified by…”
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Response properties of antral mechanosensitive afferent fibers and effects of ionotropic glutamate receptor antagonists by Sengupta, J.N, Petersen, J, Peles, S, Shaker, R

“…The ionotropic glutamate receptors N-methyl- d-aspartate (NMDA) and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors are present…”
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Altered mechanosensitive properties of vagal afferent fibers innervating the stomach following gastric surgery in rats by Miranda, A, Mickle, A, Medda, B, Zhang, Z, Phillips, R.J, Tipnis, N, Powley, T.L, Shaker, R, Sengupta, J.N

“…Abstract Background and aims: Several types of gastric surgeries have been associated with early satiety, dyspepsia and food intolerances. We aimed to examine…”
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Effect of reflux‐induced inflammation on transient receptor potential vanilloid one (TRPV1) expression in primary sensory neurons innervating the oesophagus of rats by Banerjee, B., Medda, B. K., Lazarova, Z., Bansal, N., Shaker, R., Sengupta, J. N.

“…A possible mechanism of oesophageal hypersensitivity is the acid‐induced activation of transient receptor potential vanilloid receptor 1 (TRPV1) in the primary…”
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Response properties of the brainstem neurons of the cat following intra-esophageal acid–pepsin infusion by Medda, B.K., Sengupta, J.N., Lang, I.M., Shaker, R.

“…Studies in humans have documented that acute acid infusion into the esophagus leads to decrease in threshold for sensations to mechanical distension of the…”
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Kappa, but not mu or delta, opioids attenuate responses to distention of afferent fibers innervating the rat colon by Sengupta, JN, Su, X, Gebhart, GF

“…BACKGROUND & AIMS: Discomfort and pain are the principal conscious sensations that arise from the viscera, and both are increased in frequency and intensity in…”
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Effects of Opioids on Mechanosensitive Pelvic Nerve Afferent Fibers Innervating the Urinary Bladder of the Rat by Su, X, Sengupta, J. N, Gebhart, G. F

“…X. Su , J. N. Sengupta , and G. F. Gebhart The University of Iowa, College of Medicine, Department of Pharmacology, Bowen Science Building, Iowa City, Iowa…”
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Differential c-Fos expression in the nucleus of the solitary tract and spinal cord following noxious gastric distention in the rat by Traub, R.J, Sengupta, J.N, Gebhart, G.F

“…c-Fos has been used as a marker for activity in the spinal cord following noxious somatic or visceral stimulation. Although the viscera receive dual afferent…”
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Probiotic Lactobacillus rhamnosus GG (LGG) and prebiotic prevent neonatal inflammation‐induced visceral hypersensitivity in adult rats by Kannampalli, P., Pochiraju, S., Chichlowski, M., Berg, B. M., Rudolph, C., Bruckert, M., Miranda, A., Sengupta, J. N.

“…Background Increasing evidence indicates a positive effect of probiotics on the nervous system. The objective of this study was to determine if probiotic…”
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Effects of Kappa Opioid Receptor-Selective Agonists on Responses of Pelvic Nerve Afferents to Noxious Colorectal Distension by Su, X, Sengupta, J. N, Gebhart, G. F

“…X. Su , J. N. Sengupta , and G. F. Gebhart Department of Pharmacology, College of Medicine, The University of Iowa, Iowa City, Iowa 52242 Su, X., J. N…”
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Differential effects of mu-, delta-, and kappa-opioid receptor agonists on mechanosensitive gastric vagal afferent fibers in the rat by Ozaki, N, Sengupta, J N, Gebhart, G F

“…Single-fiber recordings were made from the decentralized right cervical vagus nerve (hyponodosal) of the rat. A total of 56 afferent fibers that responded to…”
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Colonic butyrate‐ algesic or analgesic? by Kannampalli, P., Shaker, R., Sengupta, J. N.

“…Irritable bowel syndrome (IBS) is a common health issue that is characterized by abdominal pain, abnormal bowel movements, and altered visceral perception. The…”
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