P-185PRELIMINARY RESULTS OF DIAPHRAGM PACING APPLICATION IN AMYOTROPHIC LATERAL SCLEROSIS PATIENTS: FIRST TURKISH EXPERIENCE

Objectives To share the application and results of the diaphragmatic pace stimulating system (DPSS) uses in the amyotrophic lateral sclerosis (ALS) patients for the first time in Turkey. Methods Eleven ALS patients were included in the DPSS application. In defining the DPSS indication, besides quest...

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Bibliographic Details
Published in:	Interactive cardiovascular and thoracic surgery Vol. 17; no. suppl_1; p. S48
Main Authors:	Sanli, Aydin, Sengun, I.S., Ozalevli, S., Onen, A., Itil, O.B., Tasdogen, A., Karacam, V., Savas, A. Arslan, Agaoglu, B., Ozdemir, N.
Format:	Journal Article
Language:	English
Published:	Oxford University Press 01-07-2013
Online Access:	Get full text
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Summary:	Objectives To share the application and results of the diaphragmatic pace stimulating system (DPSS) uses in the amyotrophic lateral sclerosis (ALS) patients for the first time in Turkey. Methods Eleven ALS patients were included in the DPSS application. In defining the DPSS indication, besides questioning the demographic and clinical characteristics of the patients, pulmonary function tests (PFT), arterial blood gas analysis (ABGA), diaphragmatic electromyography for the patients needing it, thoracic computed tomography and diaphragmatic thickness measurements were carried out. Average age of the patients was 57.55 ± 8.80, average disease duration was 2.64 ± 1.43 years. Four patients using mechanical ventilation (MV) had tracheostomy and three patients had percutaneous endoscopic gastrostomy. Average peripheral oxygen saturation (SpO2) value of the patients during the preoperative period was 93.91 ± 2.88%. The number of patients whose forced vital capacity value is below 45% was four. DPSS application was performed by implanting two electrodes to the areas that respond the best to the electrical stimulation of the diaphragm laparoscopically with the application of general anaesthesia. Results During the postoperative period, duration of the hospital stay of the patients was 15.64 ± 7.09 days in average. There were no technical and/or clinical problems as to DPSS application in the patients. One patient completely left the MV support. Late postoperative SpO2 value of the patients was calculated as 96%. A distinct clinical and functional recovery was seen in the patients. Conclusions It was proved that DPSS application can be carried out in ALS patients laparoscopically under general anaesthesia, and that it has positive effects to the clinical, functional and quality of life of the patients. Disclosure All authors have declared no conflicts of interest.
ISSN:	1569-9293 1569-9285
DOI:	10.1093/icvts/ivt288.185