Search Results - "Sengoku, Renpei"

Aging and Alzheimer's disease pathology by Sengoku, Renpei

“…The number of people with dementia worldwide is predicted to increase to 131.5 million by 2050. When studying dementia, understanding the basis of the…”
Get full text

Great Psychological Distress Induced by COVID-19 on Healthcare Workers in Japan by Sengoku, Renpei

Get full text

Neuropathological features of cognitive decline in Lewy body dementia by Sengoku, Renpei

“…Parkinson's disease (PD) is associated with mild cognitive impairment and dementia. The causes of cognitive impairment in PD are diverse, and some remain…”
Get full text

Lewy pathology of the esophagus correlates with the progression of Lewy body disease: a Japanese cohort study of autopsy cases by Tanei, Zen-ichi, Saito, Yuko, Ito, Shinji, Matsubara, Tomoyasu, Motoda, Atsuko, Yamazaki, Mikihiro, Sakashita, Yasuhiro, Kawakami, Ito, Ikemura, Masako, Tanaka, Shinya, Sengoku, Renpei, Arai, Tomio, Murayama, Shigeo

“…Lewy body disease (LBD) is a spectrum of progressive neurodegenerative disorders characterized by the wide distribution of Lewy bodies and neurites in the…”
Get full text

Effect of istradefylline on mood disorders in Parkinson's disease by Nagayama, Hiroshi, Kano, Osamu, Murakami, Hidetomo, Ono, Kenjiro, Hamada, Masashi, Toda, Tatsushi, Sengoku, Renpei, Shimo, Yasushi, Hattori, Nobutaka

“…AbstractDepression is the most common psychiatric complication in patients with Parkinson's disease (PD). Istradefylline, a new anti-parkinsonian agent with…”
Get full text

Morphological study of the phrenic nerve to determine a reference value for the myelinated fiber density in elderly individuals by Motoda, Atsuko, Matsubara, Tomoyasu, Tanei, Zen‐ichi, Sakashita, Yasuhiro, Yamazaki, Mikihiro, Kawakami, Ito, Sengoku, Renpei, Arai, Tomio, Maruyama, Hirofumi, Saito, Yuko, Murayama, Shigeo

“…Phrenic nerves (PNs) play an important role in respiration; however, very few morphological studies have assessed them. This study aimed to provide control…”
Get full text

Lewy pathology of the submandibular gland in Lewy body disease: A report of autopsy cases by Sakashita, Yasuhiro, Matsubara, Tomoyasu, Takata, Tadayuki, Tanei, Zen‐ichi, Motoda, Atsuko, Yamazaki, Mikihiro, Kawakami, Ito, Sengoku, Renpei, Saito, Yuko, Arai, Tomio, Yamada, Masahito, Murayama, Shigeo

“…Accumulation of phosphorylated α‐synuclein in the central and peripheral nervous systems is a histological hallmark of Lewy body disease (LBD), including…”
Get full text

Multimodal treatment, including extracorporeal shock wave therapy, for refractory chronic tension-type headache: a case report by Takekawa, Toru, Chino, Toshifumi, Yamada, Naoki, Watanabe, Shu, Abo, Masahiro, Sengoku, Renpei

“…Few reports have described multidisciplinary treatment, including extracorporeal shock wave therapy, for patients with refractory chronic tension-type…”
Get full text

Homovanillic acid and 5-hydroxyindole acetic acid as biomarkers for dementia with Lewy bodies and coincident Alzheimer's disease: An autopsy-confirmed study by Morimoto, Satoru, Takao, Masaki, Hatsuta, Hiroyuki, Nishina, Yasushi, Komiya, Tadashi, Sengoku, Renpei, Nakano, Yuta, Uchino, Akiko, Sumikura, Hiroyuki, Saito, Yuko, Kanemaru, Kazutomi, Murayama, Shigeo

“…Dementia with Lewy bodies (DLB) and Alzheimer's disease (AD) are the two most common causes of dementia. Both pathologies often coexist, and AD patients with…”
Get full text

Rasagiline does not exacerbate autonomic blood pressure dysregulation in early or mild Parkinson’s disease by Oka, Hisayoshi, Sengoku, Renpei, Nakahara, Atsuo, Yamazaki, Mikihiro

“…•Blood pressure dysregulation is important in Parkinson’s disease.•Anti-Parkinsonian drugs that have less effect on blood pressure should be used.•Some…”
Get full text

Japanese version of the Montreal Cognitive Assessment cut‐off score to clarify improvement of mild cognitive impairment after exercise training in community‐dwelling older adults by Nara, Marina, Sugie, Masamitsu, Takahashi, Tetsuya, Koyama, Teruyuki, Sengoku, Renpei, Fujiwara, Yoshinori, Obuchi, Shuichi, Harada, Kazumasa, Kyo, Shunei, Ito, Hideki

“…Aim Physical exercise improves cognitive function in people with mild cognitive impairment (MCI). However, information about whether the degree of MCI before…”
Get full text

Parkinson's disease with a typical clinical course of 17 years overlapped by Creutzfeldt-Jakob disease: an autopsy case report by Kubo, Shin-Ichiro, Matsubara, Tomoyasu, Taguchi, Takeshi, Sengoku, Renpei, Takeuchi, Atsuko, Saito, Yuko

“…Late-stage Parkinson's disease (PD) often presents with neuropsychiatric symptoms such as dementia, psychosis, excessive daytime sleepiness, apathy,…”
Get full text

Neurofibrillary tangle-predominant dementia followed by amyloid β pathology: a clinico-radio-pathological case providing insights into current disease-modifying therapeutic strategy by Matsubara, Tomoyasu, Ishii, Kenji, Saito, Yoko, Tokumaru, Aya Midori, Arakawa, Akira, Hara, Manato, Kurihara, Masanori, Sengoku, Renpei, Kanemaru, Kazutomi, Iwata, Atsushi, Arai, Tomio, Miyashita, Akinori, Ikeuchi, Takeshi, Hasegawa, Masato, Murayama, Shigeo, Saito, Yuko

Get full text

Evaluating the impact of adjunctive istradefylline on the cumulative dose of levodopa-containing medications in Parkinson's disease: study protocol for the ISTRA ADJUST PD randomized, controlled study by Hatano, Taku, Kano, Osamu, Sengoku, Renpei, Yoritaka, Asako, Suzuki, Keisuke, Nishikawa, Noriko, Mukai, Yohei, Nomura, Kyoichi, Yoshida, Norihito, Seki, Morinobu, Matsukawa, Miho Kawabe, Terashi, Hiroo, Kimura, Katsuo, Tashiro, Jun, Hirano, Shigeki, Murakami, Hidetomo, Joki, Hideto, Uchiyama, Tsuyoshi, Shimura, Hideki, Ogaki, Kotaro, Fukae, Jiro, Tsuboi, Yoshio, Takahashi, Kazushi, Yamamoto, Toshimasa, Yanagisawa, Naotake, Nagayama, Hiroshi

“…Levodopa remains the most effective symptomatic treatment for Parkinson's disease (PD) more than 50 years after its clinical introduction. However, the onset…”
Get full text

Anhedonia and its correlation with clinical aspects in Parkinson's disease by Nagayama, Hiroshi, MD, PhD, Maeda, Tetsuya, MD, PhD, Uchiyama, Tsuyoshi, MD, PhD, Hashimoto, Masaya, MD, PhD, Nomoto, Nobuatsu, MD, PhD, Kano, Osamu, MD, PhD, Takahashi, Tatsuya, MD, PhD, Terashi, Hiroo, MD, PhD, Hamada, Shinsuke, MD, Hasegawa, Takafumi, MD, PhD, Hatano, Taku, MD, PhD, Takahashi, Tetsuya, MD, PhD, Baba, Yasuhiko, MD, PhD, Sengoku, Renpei, MD, PhD, Watanabe, Hirohisa, MD, PhD, Inoue, Manabu, MD, PhD, Kadowaki, Taro, MD, PhD, Kaneko, Satoshi, MD, PhD, Shimura, Hideki, MD, Kubo, Shin-ichiro, MD, PhD

“…Abstract Anhedonia is one of the non-motor symptoms observed in the Parkinson ' s disease (PD). However, there is no clear relationship between anhedonia and…”
Get full text

Impact of Istradefylline on Levodopa Dose Escalation in Parkinson’s Disease: ISTRA ADJUST PD Study, a Multicenter, Open-Label, Randomized, Parallel-Group Controlled Study by Hatano, Taku, Sengoku, Renpei, Nagayama, Hiroshi, Yanagisawa, Naotake, Yoritaka, Asako, Suzuki, Keisuke, Nishikawa, Noriko, Mukai, Yohei, Nomura, Kyoichi, Yoshida, Norihito, Seki, Morinobu, Matsukawa, Miho Kawabe, Terashi, Hiroo, Kimura, Katsuo, Tashiro, Jun, Hirano, Shigeki, Murakami, Hidetomo, Joki, Hideto, Uchiyama, Tsuyoshi, Shimura, Hideki, Ogaki, Kotaro, Fukae, Jiro, Tsuboi, Yoshio, Takahashi, Kazushi, Yamamoto, Toshimasa, Kaida, Kenichi, Ihara, Ryoko, Kanemaru, Kazutomi, Kano, Osamu

“…Introduction A higher levodopa dose is a risk factor for motor complications in Parkinson’s disease (PD). Istradefylline (IST) is used as adjunctive treatment…”
Get full text

Analysis of the Adrenal Gland Is Useful for Evaluating Pathology of the Peripheral Autonomic Nervous System in Lewy Body Disease by Fumimura, Yuichi, Ikemura, Masako, Saito, Yuko, Sengoku, Renpei, Kanemaru, Kazutomi, Sawabe, Motoji, Arai, Tomio, Ito, Genta, Iwatsubo, Takeshi, Fukayama, Masashi, Mizusawa, Hidehiro, Murayama, Shigeo

“…ABSTRACTLewy body disease is defined as Lewy body-related neuronal degeneration involving the nigrostriatal system, limbic-neocortical system, and peripheral…”
Get full text

Stroke patients with cerebral microbleeds on MRI scans have arteriolosclerosis as well as systemic atherosclerosis by Shimoyama, Takashi, Iguchi, Yasuyuki, Kimura, Kazumi, Mitsumura, Hidetaka, Sengoku, Renpei, Kono, Yu, Morita, Masayo, Mochio, Soichiro

“…Cerebral microbleeds (CMBs) are recognized as a manifestation of arteriolosclerosis in cerebral small vessels. However, little is known regarding whether…”
Get full text

Malignant Middle Cerebral Artery Infarction Resulting from Dissection of Middle Cerebral Artery by Sakuta, Kenichi, MD, Sengoku, Renpei, MD, Mitsumura, Hidetaka, MD, Kono, Yu, MD, Kan, Issei, MD, Kaku, Shogo, MD, Iguchi, Yasuyuki, MD

“…A 30-year-old man presented with headache, left hemiparesis, and uncal herniation. Magnetic resonance imaging showed acute infarction in the right middle…”
Get full text

The current state of the New York Brain Bank and a proposal for the establishment of the brain bank network in Japan by Sengoku, Renpei

“…Brain banks are becoming increasingly important due to a worldwide decline in autopsy rates, and the consequent shortage of tissue for research purposes. The…”
Get more information