Search Results - "Sengelov, Henrik"
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Epidemiology and Clinical Significance of Secondary and Therapy-Related Acute Myeloid Leukemia: A National Population-Based Cohort Study
Published in Journal of clinical oncology (01-11-2015)“…Secondary and therapy-related acute myeloid leukemia (sAML and tAML, respectively) remain therapeutic challenges. Still, it is unclear whether their inferior…”
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Detection of the novel HLA allele, HLA‐DRB108:112, identified in a Danish family
Published in HLA (01-02-2023)“…HLA‐DRB1*08:112 differs from HLA‐DRB1*08:01 in exon 2 at amino acid 62; asparagine to lysine substitution…”
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Cytokine autoantibodies are stable throughout the haematopoietic stem cell transplantation course and are associated with distinct biomarker and blood cell profiles
Published in Scientific reports (14-12-2021)“…Cytokine-specific autoantibodies (c-aAbs) represent an emerging field in endogenous immunodeficiencies, and the immunomodulatory potential of c-aAbs is now…”
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Ocular graft-versus-host disease and dry eye disease after paediatric haematopoietic stem cell transplantation - incidence and risk factors
Published in Bone marrow transplantation (Basingstoke) (01-03-2022)“…Ocular graft-versus-host disease (oGVHD) contributes substantially to morbidity after allogeneic haematopoietic stem cell transplantation (HSCT) but is…”
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Chronic ocular graft-versus-host disease after allogeneic haematopoietic stem cell transplantation in Denmark – factors associated with risks and rates in adults according to conditioning regimen
Published in Bone marrow transplantation (Basingstoke) (01-01-2021)“…We investigated risks and hazard rates of developing chronic ocular graft-versus-host disease (oGVHD) in a large nationwide, single centre study by using the…”
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Insulin-Like Growth Factor Gene Polymorphisms Predict Clinical Course in Allogeneic Hematopoietic Stem Cell Transplantation
Published in Frontiers in immunology (24-07-2020)“…Allogeneic hematopoietic stem cell transplantation (HSCT) is challenged by significant toxicities that are propagated by systemic inflammation caused by…”
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Metabolic Potential of the Gut Microbiome Is Significantly Impacted by Conditioning Regimen in Allogeneic Hematopoietic Stem Cell Transplantation Recipients
Published in International journal of molecular sciences (01-10-2022)“…Allogeneic hematopoietic stem cell transplantation (aHSCT) is a putative curative treatment for malignant hematologic disorders. During transplantation, the…”
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Identification of the novel HLA allele, HLA‐DPA101:46, identified in a man of Serbian origin
Published in HLA : immune response genetics (01-07-2021)“…HLA‐DPA1*01:46 differs from HLA‐DPA1*01:03 in exon 2 at amino acid 85; Aspartate to Asparagine substitution…”
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Impact of Antibiotic Treatment on the Gut Microbiome and its Resistome in Hematopoietic Stem Cell Transplant Recipients
Published in The Journal of infectious diseases (28-06-2023)“…Abstract Antibiotic-resistant bacterial infections are increasingly an issue in allogenic hematopoietic stem cell transplant patients. How antibiotic treatment…”
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Evaluation of infliximab as second-line treatment of acute graft versus host disease -validating response on day 7 and 28 as predictors of survival
Published in Bone marrow transplantation (Basingstoke) (01-07-2018)“…Several immunosuppressive drugs have been proposed for second-line treatment of steroid-refractory acute graft versus host disease (aGvHD) after allogeneic…”
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Epidemiology of bloodstream infections after myeloablative and non‐myeloablative allogeneic hematopoietic stem cell transplantation: A single‐center cohort study
Published in Transplant infectious disease (01-10-2017)“…Background Patients who undergo allogeneic hematopoietic stem cell transplantation (allo‐HSCT) often develop bloodstream infections (BSI). We aimed to describe…”
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Clinical activity of azacitidine in patients who relapse after allogeneic stem cell transplantation for acute myeloid leukemia
Published in Haematologica (Roma) (01-07-2016)“…Disease relapse is the most common cause of treatment failure after allogeneic stem cell transplantation for acute myeloid leukemia and myelodysplastic…”
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Allogeneic Hematopoietic Stem-Cell Transplantation for Acute Myeloid Leukemia in Remission: Comparison of Intravenous Busulfan Plus Cyclophosphamide (Cy) Versus Total-Body Irradiation Plus Cy As Conditioning Regimen—A Report From the Acute Leukemia Working Party of the European Group for Blood and Marrow Transplantation
Published in Journal of clinical oncology (01-10-2013)“…Cyclophosphamide (Cy) combined with total-body irradiation (TBI) or with busulfan (Bu) are currently the most common myeloablative regimens used in allogeneic…”
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Associations Between Mental Disorders in Donors and Matched Recipients of Hematopoietic Stem Cell Transplants: A Population-Based Cohort Study
Published in Biological psychiatry global open science (01-11-2024)“…Immunological mechanisms have been implicated in the development of mental disorders, and interestingly, case reports have suggested that hematopoietic stem…”
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Bone marrow toxicity and immune reconstitution in melanoma and non-melanoma solid cancer patients after non-myeloablative conditioning with chemotherapy and checkpoint inhibition
Published in Cytotherapy (Oxford, England) (01-08-2021)“…Lymphodepletion with non-myeloablative (NMA) chemotherapy is currently a prerequisite for adoptive cell therapy (ACT). ACT based on tumor-infiltrating…”
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Improved Overall Survival, Relapse-Free-Survival, and Less Graft-vs.-Host-Disease in Patients With High Immune Reconstitution of TCR Gamma Delta Cells 2 Months After Allogeneic Stem Cell Transplantation
Published in Frontiers in immunology (22-08-2019)“…T-cell receptor (TCR) γδ cells are perceived as innate-like effector cells with the possibility of mediating graft-vs. -tumor (GVT) without causing…”
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The impact of pre-transplantation diabetes and obesity on acute graft-versus-host disease, relapse and death after allogeneic hematopoietic cell transplantation: a study from the EBMT Transplant Complications Working Party
Published in Bone marrow transplantation (Basingstoke) (01-02-2024)“…Obesity and diabetes can modulate immune responses, which may impact allogeneic HCT outcomes and GvHD. From the EBMT registry, we included 36,539 adult…”
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