Search Results - "Seng, Wu Yuan"

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    Anticancer Activities of Surfactin and Potential Application of Nanotechnology Assisted Surfactin Delivery by Wu, Yuan-Seng, Ngai, Siew-Ching, Goh, Bey-Hing, Chan, Kok-Gan, Lee, Learn-Han, Chuah, Lay-Hong

    Published in Frontiers in pharmacology (26-10-2017)
    “…Surfactin, a cyclic lipopeptide biosurfactant produced by various strains of Bacillus genus, has been shown to induce cytotoxicity against many cancer types,…”
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    Journal Article
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    Biological Activities of Paeonol in Cardiovascular Diseases: A Review by Vellasamy, Shalini, Murugan, Dharmani, Abas, Razif, Alias, Aspalilah, Seng, Wu Yuan, Woon, Choy Ker

    Published in Molecules (Basel, Switzerland) (17-08-2021)
    “…Paeonol is a naturally existing bioactive compound found in the root bark of and it is traditionally used in Chinese medicine for the prevention and management…”
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    Natural Bioactive Compounds Targeting NADPH Oxidase Pathway in Cardiovascular Diseases by Sofiullah, Siti Sarah M, Murugan, Dharmani Devi, Muid, Suhaila Abd, Seng, Wu Yuan, Kadir, Sharifah Zamiah Syed Abdul, Abas, Razif, Ridzuan, Nurul Raudzah Adib, Zamakshshari, Nor Hisam, Woon, Choy Ker

    Published in Molecules (Basel, Switzerland) (20-01-2023)
    “…Cardiovascular disease (CVD) is the leading cause of death worldwide, in both developed and developing countries. According to the WHO report, the morbidity…”
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    SLC1A2 Gene Polymorphism Influences Methamphetamine-Induced Psychosis by Yahya, Dayang Nooreffazleen, Guad, Rhanye Mac, Wu, Yuan-Seng, Gan, Siew Hua, Gopinath, Subash C B, Zakariah, Hasif Adli, Rashid, Rusdi Abdul, Sim, Maw Shin

    Published in Journal of personalized medicine (31-01-2023)
    “…is a gene encoded for the excitatory amino acid transporter 2 which is responsible for glutamate reuptake from the synaptic cleft in the central nervous…”
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    Molecular Mechanisms of Antiviral Agents against Dengue Virus by Lee, Michelle Felicia, Wu, Yuan Seng, Poh, Chit Laa

    Published in Viruses (01-03-2023)
    “…Dengue is a major global health threat causing 390 million dengue infections and 25,000 deaths annually. The lack of efficacy of the licensed Dengvaxia vaccine…”
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    Antiviral peptides against SARS-CoV-2: therapeutic targets, mechanistic antiviral activity, and efficient delivery by Essa, Raahilah Zahir, Wu, Yuan-Seng, Batumalaie, Kalaivani, Sekar, Mahendran, Poh, Chit-Laa

    Published in Pharmacological reports (01-12-2022)
    “…The global pandemic of COVID-19 is a serious public health concern. Over 625 million confirmed cases and more than 6 million deaths have been recorded…”
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    Journal Article
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    Paracrine IL-6 signaling mediates the effects of pancreatic stellate cells on epithelial-mesenchymal transition via Stat3/Nrf2 pathway in pancreatic cancer cells by Wu, Yuan Seng, Chung, Ivy, Wong, Won Fen, Masamune, Atsushi, Sim, Maw Shin, Looi, Chung Yeng

    “…We previously showed that pancreatic stellate cells (PSC) secreted interleukin (IL)-6 and promoted pancreatic ductal adenocarcinoma (PDAC) cell proliferation…”
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    Molecular dynamics simulations reveal the inhibitory mechanism of Withanolide A against α-glucosidase and α-amylase by Oyewusi, Habeebat Adekilekun, Wu, Yuan-Seng, Safi, Sher Zaman, Wahab, Roswanira Abdul, Hatta, Mohd Hayrie Mohd, Batumalaie, Kalaivani

    “…Diabetes mellitus (DM) is a global chronic disease characterized by hyperglycemia and insulin resistance. The unsavory severe gastrointestinal side-effects of…”
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    Alcohol-associated liver disease: A review on its pathophysiology, diagnosis and drug therapy by Subramaniyan, Vetriselvan, Chakravarthi, Srikumar, Jegasothy, Ravindran, Seng, Wu Yuan, Fuloria, Neeraj Kumar, Fuloria, Shivkanya, Hazarika, Iswar, Das, Anju

    Published in Toxicology reports (01-01-2021)
    “…•Chronic intake of alcohol initiates a pathogenic process that involves the production of protein-aldehyde adducts, and release of cytokines.•Involved gene…”
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    A review on cytomegalovirus in patients with autoimmune inflammatory rheumatic diseases: Prevalence, clinical spectrum, treatment, and antiviral prophylaxis by Brianna, Brianna, Masnammany, Adrian Mark, Wu, Yuan Seng

    Published in Proceedings of Singapore Healthcare (01-03-2024)
    “…Human cytomegalovirus (CMV) is a highly infectious virus that is prevalent among adults worldwide. In immunocompetent individuals, CMV infection rarely causes…”
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    Selective phytochemicals targeting pancreatic stellate cells as new anti-fibrotic agents for chronic pancreatitis and pancreatic cancer by Ramakrishnan, Puvanesswaray, Loh, Wei Mee, Gopinath, Subash C.B., Bonam, Srinivasa Reddy, Fareez, Ismail M., Mac Guad, Rhanye, Sim, Maw Shin, Wu, Yuan Seng

    Published in Acta pharmaceutica Sinica. B (01-03-2020)
    “…Activated pancreatic stellate cells (PSCs) have been widely accepted as a key precursor of excessive pancreatic fibrosis, which is a crucial hallmark of…”
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    Anti- COVID-19 drug discovery by flavonoid derivatives: an extensive computational drug design approach by Banerjee, Subhasis, Mukherjee, Souvik, Mohsin Kazi, Sen, Kalyan Kumar, Das, Arka, Hasan, Raquibul, Wu, Yuan-Seng, Eftekhari, Aziz, Das, Sreemoy Kanti, Nur-E-Alam, Mohammad, Sarker, Md Moklesur Rahman, Nur Azlina, Mohd Fahami

    Published in Cellular and Molecular Biology (08-09-2024)
    “…The present study deals with the in-silico analyses of several flavonoid derivatives to explore COVID-19 through pharmacophore modelling, molecular docking,…”
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