Search Results - "Seng, Tan Poh"

Acute-on-chronic liver failure in a multi-ethnic Asian city:A comparison of patients identified by Asia-Pacific Association for the Study of the Liver and European Association for the Study of the Liver definitions by Selva Rajoo, Anandraj, Lim, Seng-Gee, Phyo, Wah Wah, Tun, Thandar, Dan, Yock-Young, Lee, Yin-Mei, Low, How-Cheng, Lim, Kieron, Tan, Poh-Seng, Lee, Guan-Huei

“…AIM To explore the applicability of the Asia-Pacific Association for the Study of the Liver(APASL) and European Association for the Study of the Liver(EASL)…”
Get full text

A study of 3013 cases of hepatocellular carcinoma: Etiology and therapy before and during the current decade by Lim, Miao‐Shan, Goh, George B‐B, Chang, Jason P‐E, Low, Jee‐Keem, Shelat, Vishalkumar G, Huey, Terence C‐W, Dan, Yock‐Young, Kow, Alfred, Shridhar, Iyer, Tan, Poh‐Seng, Junnarkar, Sameer P, Tan, Chee‐Kiat

“…Background and Aim Hepatocellular carcinoma (HCC) is a significant global problem. With advances in HCC diagnosis and therapy, our hypothesis is that there are…”
Get full text

Comparable Outcomes in Early Hepatocellular Carcinomas Treated with Trans-Arterial Chemoembolization and Radiofrequency Ablation by Tay, Benjamin Wei Rong, Huang, Daniel Q, Mark, Muthiah, Thong, Neo Wee, Guan Huei, Lee, Gee, Lim Seng, Cheng, Low How, Mei, Lee Yin, Thurairajah, Prem, Chen, Lim Jia, Ng, Cheng Han, Lim, Wen Hui, Tan, Darren Jun Hao, Maureen, Da Costa, Alfred, Kow Wei Chieh, Ganpathi, Iyer Shridar, Seng, Tan Poh, Young, Dan Yock

“…The guidelines recommend radiofrequency ablation (RFA) for early hepatocellular carcinomas that are less than 3 cm and trans-arterial chemoembolization (TACE)…”
Get full text

Sunitinib-associated hyperammonemic encephalopathy successfully managed with higher intensity conventional hemodialysis: A case report by Haroon, Sabrina, Ko, Stephanie, Wong, Alvin, Tan, Poh-Seng, Lee, Evan, Lau, Titus

“…Hyperammonemia encephalopathy is a rare but severe complication that has been reported in association with the use of sunitinib, a tyrosine kinase inhibitor…”
Get full text

Progenitor cell markers predict outcome of patients with hepatocellular carcinoma beyond Milan criteria undergoing liver transplantation by Miltiadous, Oriana, Sia, Daniela, Hoshida, Yujin, Fiel, Maria Isabel, Harrington, Andrew N, Thung, Swan N, Tan, Poh Seng, Dong, Hui, Revill, Kate, Chang, Charissa Y, Roayaie, Sasan, Byrne, Thomas J, Mazzaferro, Vincenzo, Rakela, Jorge, Florman, Sander, Schwartz, Myron, Llovet, Josep M

“…Graphical abstract…”
Get full text

Imaging-based surrogate markers of transcriptome subclasses and signatures in hepatocellular carcinoma: preliminary results by Taouli, Bachir, Hoshida, Yujin, Kakite, Suguru, Chen, Xintong, Tan, Poh Seng, Sun, Xiaochen, Kihira, Shingo, Kojima, Kensuke, Toffanin, Sara, Fiel, M. Isabel, Hirschfield, Hadassa, Wagner, Mathilde, Llovet, Josep M.

“…Objectives In this preliminary study, we examined whether imaging-based phenotypes are associated with reported predictive gene signatures in hepatocellular…”
Get full text

DNA hypomethylation induces a DNA replication-associated cell cycle arrest to block hepatic outgrowth in uhrf1 mutant zebrafish embryos by Jacob, Vinitha, Chernyavskaya, Yelena, Chen, Xintong, Tan, Poh Seng, Kent, Brandon, Hoshida, Yujin, Sadler, Kirsten C

“…UHRF1 (ubiquitin-like, containing PHD and RING finger domains, 1) recruits DNMT1 to hemimethylated DNA during replication and is essential for maintaining DNA…”
Get full text

Clinicopathological indices to predict hepatocellular carcinoma molecular classification by Tan, Poh Seng, Nakagawa, Shigeki, Goossens, Nicolas, Venkatesh, Anu, Huang, Tiangui, Ward, Stephen C., Sun, Xiaochen, Song, Won-Min, Koh, Anna, Canasto-Chibuque, Claudia, Deshmukh, Manjeet, Nair, Venugopalan, Mahajan, Milind, Zhang, Bin, Fiel, Maria Isabel, Kobayashi, Masahiro, Kumada, Hiromitsu, Hoshida, Yujin

“…Background & Aims Hepatocellular carcinoma (HCC) is the second most lethal cancer caused by lack of effective therapies. Although promising, HCC molecular…”
Get full text

Molecular subclasses of hepatocellular carcinoma predict sensitivity to fibroblast growth factor receptor inhibition by Schmidt, Benjamin, Wei, Lan, DePeralta, Danielle K., Hoshida, Yujin, Tan, Poh Seng, Sun, Xiaochen, Sventek, Janelle P., Lanuti, Michael, Tanabe, Kenneth K., Fuchs, Bryan C.

“…A recent gene expression classification of hepatocellular carcinoma (HCC) includes a poor survival subclass termed S2 representing about one‐third of all HCC…”
Get full text

Transcriptome profiling of archived sectioned formalin-fixed paraffin-embedded (AS-FFPE) tissue for disease classification by Kojima, Kensuke, April, Craig, Canasto-Chibuque, Claudia, Chen, Xintong, Deshmukh, Manjeet, Venkatesh, Anu, Tan, Poh Seng, Kobayashi, Masahiro, Kumada, Hiromitsu, Fan, Jian-Bing, Hoshida, Yujin

“…Archived tissues from previously completed prospective trials represent invaluable resource for biomarker development. However, such specimens are often stored…”
Get full text

Decreased miR122 in hepatocellular carcinoma leads to chemoresistance with increased arginine by Kishikawa, Takahiro, Otsuka, Motoyuki, Tan, Poh Seng, Ohno, Motoko, Sun, Xiaochen, Yoshikawa, Takeshi, Shibata, Chikako, Takata, Akemi, Kojima, Kentaro, Takehana, Kenji, Ohishi, Maki, Ota, Sana, Noyama, Tomoyuki, Kondo, Yuji, Sato, Masaya, Soga, Tomoyoshi, Hoshida, Yujin, Koike, Kazuhiko

“…Reduced expression of microRNA122 (miR122), a liver-specific microRNA, is frequent in hepatocellular carcinoma (HCC). However, its biological significances…”
Get full text

A comparison of surgery versus transcatheter angiographic embolization in the treatment of nonvariceal upper gastrointestinal bleeding uncontrolled by endoscopy by Ang, Daphne, Teo, Eng Kiong, Tan, Andrew, Ibrahim, Salleh, Tan, Poh Seng, Ang, Tiing Leong, Fock, Kwong Ming

“…BACKGROUNDPatients with recurrent nonvariceal upper gastrointestinal bleeding who have failed endoscopic therapy pose a challenge. Percutaneous transcatheter…”
Get full text

Incidence and Phenotype of Inflammatory Bowel Disease Based on Results From the Asia-Pacific Crohn's and Colitis Epidemiology Study by Ng, Siew C, Tang, Whitney, Ching, Jessica Y, Wong, May, Chow, Chung Mo, Hui, A.J, Wong, T.C, Leung, Vincent K, Tsang, Steve W, Yu, Hon Ho, Li, Mo Fong, Ng, Ka Kei, Kamm, Michael A, Studd, Corrie, Bell, Sally, Leong, Rupert, de Silva, H. Janaka, Kasturiratne, Anuradhani, Mufeena, M.N.F, Ling, Khoon Lin, Ooi, Choon Jin, Tan, Poh Seng, Ong, David, Goh, Khean L, Hilmi, Ida, Pisespongsa, Pises, Manatsathit, Sathaporn, Rerknimitr, Rungsun, Aniwan, Satimai, Wang, Yu Fang, Ouyang, Qin, Zeng, Zhirong, Zhu, Zhenhua, Chen, Min Hu, Hu, Pin Jin, Wu, Kaichun, Wang, Xin, Simadibrata, Marcellus, Abdullah, Murdani, Wu, Justin Cy, Sung, Joseph J.Y, Chan, Francis K.L

“…Background & Aims Inflammatory bowel diseases (IBD) are becoming more common in Asia, but epidemiologic data are lacking. The Asia-Pacific Crohn’s and Colitis…”
Get full text

Switching to or Add-on Peginterferon in Patients on Nucleos(t)ide Analogues for Chronic Hepatitis B: The SWAP RCT by Lim, Seng Gee, Yang, Wei Lyn, Ngu, Jing Hieng, Chang, Jason, Tan, Jessica, Ahmed, Taufique, Dan, Yock Young, Lim, Kieron, Lee, Yin Mei, Lee, Guan Huei, Tan, Poh Seng, Wai, Khin Lay, Phyo, Wah Wah, Khine, Htet Htet Toe Wai, Lee, Chris, Tay, Amy, Chan, Edwin

“…The optimal therapeutic strategy in nucleoside analogue (NA) experienced chronic hepatitis B (CHB) using peginterferon is still unclear; hence we explored a…”
Get full text

Asian Liver Transplant Network Clinical Guidelines on Immunosuppression in Liver Transplantation by Tan, Poh Seng, Muthiah, Mark D, Koh, Tsingyi, Teoh, Yee Leong, Chan, Albert, Kow, Alfred, Zheng, Qishi, Kwon, Choon Hyuck David, Lee, Guan Huei, Lesmana, Cosmas Rinaldi A, de Villa, Vanessa, Fung, James, Lim, Kieron

“…Most management guidelines and much of the available clinical trial evidence for immunosuppressants in liver transplantation (LT) pertain to Western practice…”
Get full text

Comparative biomarkers for HBsAg loss with antiviral therapy shows dominant influence of quantitative HBsAg (qHBsAg) by Lim, Seng Gee, Phyo, Wah Wah, Ling, Joanna Zhi Jie, Cloherty, Gavin, Butler, Emily K., Kuhns, Mary C., McNamara, Anne L., Holzmayer, Vera, Gersch, Jeffrey, Yang, Wei Lyn, Ngu, Jing Hieng, Chang, Jason, Tan, Jessica, Ahmed, Taufique, Dan, Yock Young, Lee, Yin Mei, Lee, Guan Huei, Tan, Poh Seng, Huang, Daniel Q., Khine, Htet Toe Wai, Lee, Chris, Tay, Amy, Chan, Edwin

“…Summary Background Biomarkers such as quantitative HBsAg (qHBsAg), quantitative hepatitis B virus (HBV) core‐related antigen (qHBcrAg) and HBV RNA may be…”
Get full text

Quantitative HBeAg is a strong predictor of HBeAg loss among patients receiving pegylated interferon by Huang, Daniel Q., Shen, Liang, Phyo, Wah Wah, Cloherty, Gavin, Butler, Emily K., Kuhns, Mary C., McNamara, Anne L., Holzmayer, Vera, Gersch, Jeffrey, Anderson, Mark, Yang, Wei Lyn, Ngu, Jing Hieng, Chang, Jason, Tan, Jessica, Ahmed, Taufique, Dan, Yock Young, Lee, Yin Mei, Lee, Guan Huei, Tan, Poh Seng, Muthiah, Mark, Khine, Htet Toe Wai, Lee, Chris, Tay, Amy, Lim, Seng Gee

“…HBeAg loss is an important endpoint for antiviral therapy in chronic hepatitis B (CHB), however there are no reliable biomarkers to identify patients who will…”
Get full text

A genomic and clinical prognostic index for hepatitis C-related early-stage cirrhosis that predicts clinical deterioration by King, Lindsay Y, Canasto-Chibuque, Claudia, Johnson, Kara B, Yip, Shun, Chen, Xintong, Kojima, Kensuke, Deshmukh, Manjeet, Venkatesh, Anu, Tan, Poh Seng, Sun, Xiaochen, Villanueva, Augusto, Sangiovanni, Angelo, Nair, Venugopalan, Mahajan, Milind, Kobayashi, Masahiro, Kumada, Hiromitsu, Iavarone, Massimo, Colombo, Massimo, Fiel, Maria Isabel, Friedman, Scott L, Llovet, Josep M, Chung, Raymond T, Hoshida, Yujin

“…The number of patients with HCV-related cirrhosis is increasing, leading to a rising risk of complications and death. Prognostic stratification in patients…”
Get more information

Comparison of hepatocellular carcinoma between the current decade and the past - a study of 3,013 cases by Lim, Miao-Shan, George Goh, Boon Bee, Jason Chang, Pik Eu, Low, Jee-Keem, Shelat, Vishalkumar Grishchandra, Cheong, Wei-Huey Terence, Dan, Yock-Young, Kow, Alfred, Iyer, Shridhar, Tan, Poh-Seng, Junnarkar, Sameer Padmakumar, Tan, Chee-Kiat

Get full text

THU507 - Comparison of hepatocellular carcinoma between the current decade and the past - a study of 3,013 cases by Lim, Miao-Shan, George Goh, Boon Bee, Jason Chang, Pik Eu, Low, Jee-Keem, Shelat, Vishalkumar Grishchandra, Cheong, Wei-Huey Terence, Dan, Yock-Young, Kow, Alfred, Iyer, Shridhar, Tan, Poh-Seng, Junnarkar, Sameer Padmakumar, Tan, Chee-Kiat

Get full text