Search Results - "Senetra, Alexandria"

The Lack of Contribution of 7-Hydroxymitragynine to the Antinociceptive Effects of Mitragynine in Mice: A Pharmacokinetic and Pharmacodynamic Study by Berthold, Erin C, Kamble, Shyam H, Raju, Kanumuri S, Kuntz, Michelle A, Senetra, Alexandria S, Mottinelli, Marco, León, Francisco, Restrepo, Luis F, Patel, Avi, Ho, Nicholas P, Hiranita, Takato, Sharma, Abhisheak, McMahon, Lance R, McCurdy, Christopher R

“…Kratom ( ), a Southeast Asian tree, has been used for centuries in pain relief and mitigation of opium withdrawal symptoms. Mitragynine (MTG), the major kratom…”
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FABP5 is important for cognitive function and is an important regulator of the physiological effects and pharmacokinetics of acute Δ9 tetrahydrocannabinol inhalation in mice by Penman, Samantha L., Roeder, Nicole M., Berthold, Erin C., Senetra, Alexandria S., Marion, Matthew, Richardson, Brittany J., White, Olivia, Fearby, Nathan L., McCurdy, Christopher R., Hamilton, John, Sharma, Abhisheak, Thanos, Panayotis K.

“…Fatty acid binding protein 5 (FABP5) interacts with the endocannabinoid system in the brain via intracellular transport of anandamide, as well as…”
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Pharmacokinetics of delta-9-tetrahydrocannabinol following acute cannabis smoke exposure in mice; effects of sex, age, and strain by Gazarov, Emely A., Zequeira, Sabrina, Senetra, Alexandria S., Howard, John, Sharma, Abhisheak, McCurdy, Christopher R., Lewis, Jada, Bizon, Jennifer L., Setlow, Barry

“…Increased use of cannabis and cannabinoids for recreational and medical purposes has led to a growth in research on their effects in animal models. The…”
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Correlating Lipid Membrane Permeabilities of Imidazolium Ionic Liquids with their Cytotoxicities on Yeast, Bacterial, and Mammalian Cells by Cook, Kendall, Tarnawsky, Katharine, Swinton, Alana J, Yang, Daniel D, Senetra, Alexandria S, Caputo, Gregory A, Carone, Benjamin R, Vaden, Timothy D

“…Alkyl-imidazolium chloride ionic liquids (ILs) have been broadly studied for biochemical and biomedical technologies. They can permeabilize lipid bilayer…”
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Pharmacokinetic Interaction of Kratom and Cannabidiol in Male Rats by Berthold, Erin C, Kamble, Shyam H, Kanumuri, Siva Rama Raju, Kuntz, Michelle A, Senetra, Alexandria S, Chiang, Yi-Hua, Mukhopadhyay, Sushobhan, McCurdy, Christopher R, Sharma, Abhisheak

“…Kratom and cannabidiol products are used to self-treat a variety of conditions, including anxiety and pain, and to elevate mood. Research into the individual…”
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Synergistic interactions of ionic liquids and antimicrobials improve drug efficacy by Yang, Daniel D., Paterna, Nicholas J., Senetra, Alexandria S., Casey, Kaitlyn R., Trieu, Phillip D., Caputo, Gregory A., Vaden, Timothy D., Carone, Benjamin R.

“…Combinations of ionic liquids (ILs) with antimicrobial compounds have been shown to produce synergistic activities in model liposomes. In this study,…”
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Comparative Pharmacokinetics of Commercially Available Cannabidiol Isolate, Broad-Spectrum, and Full-Spectrum Products by Berthold, Erin C., Kamble, Shyam H., Kanumuri, Siva Rama Raju, Kuntz, Michelle A., Senetra, Alexandria S., Chiang, Yi-Hua, McMahon, Lance R., McCurdy, Christopher R., Sharma, Abhisheak

“…Background and Objectives A wide variety of products containing cannabidiol (CBD) are available on the commercial market. One of the most common products, CBD…”
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Investigation of the structure‐activity relationship in ponericin L1 from Neoponera goeldii by Senetra, Alexandria S., Necelis, Matthew R., Caputo, Gregory A.

“…Naturally derived antimicrobial peptides have been an area of great interest because of high selectivity against bacterial targets over host cells and the…”
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Preclinical pharmacokinetic studies of villocarine A, an active Uncaria alkaloid by Chiang, Yi-Hua, Chear, Nelson Jeng-Yeou, Berthold, Erin C, Kuntz, Michelle A, Kanumuri, Siva Rama Raju, Senetra, Alexandria S, Ramanathan, Surash, McCurdy, Christopher R, Sharma, Abhisheak

“…Villocarine A is a bioactive indole alkaloid isolated from the Uncaria genus. It has demonstrated vasorelaxation activity and potential to protect the central…”
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Multiple-Dose Pharmacokinetics and Safety of Mitragynine, the Major Alkaloid of Kratom, in Rats by Chiang, Yi-Hua, Berthold, Erin C., Kuntz, Michelle A., Kanumuri, Siva Rama Raju, Senetra, Alexandria S., Mukhopadhyay, Sushobhan, Hampson, Aidan J., McCurdy, Christopher R., Sharma, Abhisheak

“…This study reports the steady-state pharmacokinetic parameters for mitragynine and characterizes its elimination in male and female rats. Four male and female…”
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Guanidine-to-piperidine switch affords high affinity small molecule NPFF ligands with preference for NPFF1-R and NPFF2-R subtypes by Galal, Kareem A., Obeng, Samuel, Pallares, Victoria L.C., Senetra, Alexandria, Seabra, Maria A.B.L., Awad, Ahmed, McCurdy, Christopher R.

“…The Neuropeptide FF (NPFF) receptor system is known to modulate opioid actions and has been shown to mediate opioid-induced hyperalgesia and tolerance. The…”
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Investigation of the Sequence-Structure-Activity Relationship in Ponericin L1 from Neoponera goeldii & Synergistic Interactions of Ionic Liquids and Antimicrobials to Improve Efficacy by Senetra, Alexandria S

“…Non-traditional antimicrobials have been an area of great interest due to the increasing prevalence of antimicrobial resistance (AMR) in bacteria…”
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