Search Results - "Senecal, Adrien"

Single-Cell and Single-Molecule Analysis of Gene Expression Regulation by Vera, Maria, Biswas, Jeetayu, Senecal, Adrien, Singer, Robert H, Park, Hye Yoon

“…Recent advancements in single-cell and single-molecule imaging technologies have resolved biological processes in time and space that are fundamental to…”
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Real-Time Dynamics of RNA Polymerase II Clustering in Live Human Cells by Cisse, Ibrahim I., Izeddin, Ignacio, Causse, Sebastien Z., Boudarene, Lydia, Senecal, Adrien, Muresan, Leila, Dugast-Darzacq, Claire, Hajj, Bassam, Dahan, Maxime, Darzacq, Xavier

“…Transcription is reported to be spatially compartmentalized in nuclear transcription factories with clusters of RNA polymerase II (Pol II). However, little is…”
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Transcription Factors Modulate c-Fos Transcriptional Bursts by Senecal, Adrien, Munsky, Brian, Proux, Florence, Ly, Nathalie, Braye, Floriane E., Zimmer, Christophe, Mueller, Florian, Darzacq, Xavier

“…Transcription is a stochastic process occurring mostly in episodic bursts. Although the local chromatin environment is known to influence the bursting behavior…”
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FISH-quant: automatic counting of transcripts in 3D FISH images by Mueller, Florian, Senecal, Adrien, Tantale, Katjana, Marie-Nelly, Hervé, Ly, Nathalie, Collin, Olivier, Basyuk, Eugenia, Bertrand, Edouard, Darzacq, Xavier, Zimmer, Christophe

“…Transcription is inherently stochastic even in clonal cell populations 1. Studies at single-cell-single-molecule level enable a quantitative understanding of…”
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Transcriptional burst fraction and size dynamics during lens fiber cell differentiation and detailed insights into the denucleation process by Limi, Saima, Senecal, Adrien, Coleman, Robert, Lopez-Jones, Melissa, Guo, Peng, Polumbo, Christina, Singer, Robert H., Skoultchi, Arthur I., Cvekl, Ales

“…Genes are transcribed in irregular pulses of activity termed transcriptional bursts. Cellular differentiation requires coordinated gene expression; however, it…”
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Imaging Transcription Dynamics in Single Cancer Cells by Senecal, Adrien, Kenworthy, Charles, Lavis, Luke, Liu, Wei-Li, Singer, Robert H., Coleman, Robert A.

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Dual Inhibition of Mdmx and Mdm2 Using an Alpha-Helical P53 Stapled Peptide (ALRN-6924) As a Novel Therapeutic Strategy in Acute Myeloid Leukemia by Carvajal, Luis A., Ben-Neriah, Daniela, Senecal, Adrien, Bernard, Lumie, Narayanagari, Swathi-Rao, Kenworthy, Charles, Thiruthuvanathan, Victor, Guerlavais, Vincent, Annis, D. Allen, Bartholdy, Boris, Will, Britta, Anampa, Jesus, Mantzaris, Ioannis, Aivado, Manuel A., Singer, Robert H, Coleman, Robert, Verma, Amit, Steidl, Ulrich G.

“…While the TP53 tumor suppressor gene is mutated in more than 50% of human tumors, in Acute Myeloid Leukemia (AML) TP53 mutations are rare, occurring in less…”
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Dual inhibition of HDMX and HDM2 in acute myeloid leukemia by Carvajal, Luis, Ben-Neriah, Daniela, Senecal, Adrien, Benard, Lumie, Narayanagari, Swathi-Rao, Kenworhty, Charles, Thiruthuvanathan, Victor, Guerlavais, Vincent, Annis, Allen, Bartholdy, Boris, Will, Britta, Anampa, Jesus, Mantzaris, Ioannis, Aivado, Manuel, Singer, Robert, Coleman, Robert, Verma, Amit, Steidl, Ulrich

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