Search Results - "Sendi, Hossein"

Nanoparticle Delivery of miR-122 Inhibits Colorectal Cancer Liver Metastasis by Sendi, Hossein, Yazdimamaghani, Mostafa, Hu, Mengying, Sultanpuram, Nikhila, Wang, Jie, Moody, Amber S, McCabe, Ellie, Zhang, Jiajie, Graboski, Amanda, Li, Liantao, Rojas, Juan D, Dayton, Paul A, Huang, Leaf, Wang, Andrew Z

“…Liver metastasis is a leading cause of cancer morbidity and mortality. Thus, there has been strong interest in the development of therapeutics that can…”
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The role of liver microenvironment in hepatic metastasis by Williamson, Tovah, Sultanpuram, Nikhila, Sendi, Hossein

“…Metastasis is still poorly understood and thus further research must be conducted to provide insight into the driving factors. Novel research has revealed the…”
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Dual Role of miR-122 in Molecular Pathogenesis of Viral Hepatitis by Sendi, Hossein

“…The hepatic microRNA (miRNA), miR-122, is the most abundant miRNA within the liver, where it accounts for 70% of the total miRNA pool. It is known that…”
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miR-122 inhibition in a human liver organoid model leads to liver inflammation, necrosis, steatofibrosis and dysregulated insulin signaling by Sendi, Hossein, Mead, Ivy, Wan, Meimei, Mehrab-Mohseni, Marjan, Koch, Kenneth, Atala, Anthony, Bonkovsky, Herbert L, Bishop, Colin E

“…To investigate the role of miR-122 in the development and regression of non-alcoholic fatty liver disease (NAFLD) in vitro, we used multicellular 3D human…”
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Hepatitis C, porphyria cutanea tarda and liver iron: an update by Ryan Caballes, F., Sendi, Hossein, Bonkovsky, Herbert L.

“…Porphyria cutanea tarda (PCT) is the most common form of porphyria across the world. Unlike other forms of porphyria, which are inborn errors of metabolism,…”
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Hepatitis B and liver transplantation: Molecular and clinical features that influence recurrence and outcome by Ghaziani, Tahereh, Sendi, Hossein, Shahraz, Saeid, Zamor, Philippe, Bonkovsky, Herbert L

“…Hepatitis B virus(HBV) continues to be a major cause of morbidity and mortality worldwide. It is estimated that about 350 million people throughout the world…”
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Legalon-SIL downregulates HCV core and NS5A in human hepatocytes expressing full-length HCV by Mehrab-Mohseni, Marjan, Sendi, Hossein, Steuerwald, Nury, Ghosh, Sriparna, Schrum, Laura W, Bonkovsky, Herbert L

“…AIM： To determine the effect of Legalon-SIL （LS） on hepatitis C virus （HCV） core and NS5A expression and on heme oxygenase-1 （HMOX-1） and its transcriptional…”
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Serum measures of iron status and HFE gene mutations in patients with hepatitis B virus infection by Ghaziani, Tahereh, Alavian, Seyed-Moayed, Zali, Mohammad R., Shahraz, Saeid, Agah, Mohammdreza, Jensen, Kevin P., Ansari, Shahin, Sendi, Hossein, Lambrecht, Richard W., Covault, Jonathan, Bonkovsky, Herbert L.

“…Aim:  We tested associations between HFE mutations and hepatitis B virus (HBV) infection. We also explored measures of total body iron status and their…”
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Abstract 5033: Targeted delivery of miR-122 into hepatocytes regresses liver metastasis by Sendi, Hossein, Sultanpuram, Nikhila, Wang, Jie, Graboski, Amanda, Li, Liantao, Hu, Mengying, Huang, Leaf, Wang, Andrew Z.

“…Abstract Background: Metastatic tumors in the liver are 20 times more common than primary tumors and considered as a leading cause of mortality in several…”
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Nanoparticle Drug Delivery Can Reduce the Hepatotoxicity of Therapeutic Cargo by Yang, Feifei, Medik, Yusra, Li, Liantao, Tian, Xi, Fu, Dong, Brouwer, Kim L. R., Wagner, Kyle, Sun, Bo, Sendi, Hossein, Mi, Yu, Wang, Andrew Z.

“…Hepatotoxicity is a key concern in the clinical translation of nanotherapeutics because preclinical studies have consistently shown that nanotherapeutics…”
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Abstract 281: Culture of circulating tumor cells isolated from cancer patients with metastatic disease by Sultanpuram, Nikhila Reddy, Kim, Isaiah, Sendi, Hossein, Kanpe, Nicole, Hagen, Tilden, Wagner, Kyle, Wang, Andrew

“…Abstract OBJECTIVE: The purpose of this study is to investigate the feasibility of using decellularized tissue ECM to culture circulating tumor cells (CTCs)…”
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CCR5 [Delta] 32 mutation is not prevalent in Iranians with chronic HBV infection by Khorramdelazad, Hossein, Hakimizadeh, Elham, Hassanshahi, Gholamhossein, Rezayati, Mohammadtaghi, Sendi, Hossein, Arababadi, Mohammad Kazemi

“…CCR5 is an important chemokine receptor involved in the recruitment of specific anti-viral immune cells (e.g., NK cells and T cytotoxic cells) to the liver…”
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CCR5 Δ 32 mutation is not prevalent in Iranians with chronic HBV infection by Khorramdelazad, Hossein, Hakimizadeh, Elham, Hassanshahi, Gholamhossein, Rezayati, Mohammadtaghi, Sendi, Hossein, Arababadi, Mohammad Kazemi

“…CCR5 is an important chemokine receptor involved in the recruitment of specific anti‐viral immune cells (e.g., NK cells and T cytotoxic cells) to the liver…”
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HFE Gene Mutations in Cryptogenic Cirrhosis Patients by Sendi, Hossein, Mehrab-Mohseni, Marjan

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miR-122 decreases HCV entry into hepatocytes through binding to the 3′ UTR of OCLN mRNA by Sendi, Hossein, Mehrab-Mohseni, Marjan, Foureau, David M., Ghosh, Sriparna, Walling, Tracy L., Steuerwald, Nury, Zamor, Philippe J., Kaplan, Keith J., Jacobs, Carl, Ahrens, William A., Russo, Mark W., Clemens, Mark G., Schrum, Laura W., Bonkovsky, Herbert L.

“…Background & Aims Analysis in silico suggests that occludin (OCLN), a key receptor for HCV, is a candidate target of miR‐122; the most abundant hepatic micro…”
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Novel roles of microRNAs in hepatitis C by Sendi, Hossein

“…Approximately, 170 million people are infected by hepatitis C virus (HCV) worldwide, and of these, nearly 85% will develop chronic hepatitis C (CHC). Despite…”
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T helper and B cell escape mutations within the HBc gene in patients with asymptomatic HBV infection: a study from the South-Eastern region of Iran by Assar, Shokrollah, Arababadi, Mohammad Kazemi, Mohit, Maryam, Ahmadabadi, Behzad Nasiri, Pumpens, Paul, Khorramdelazad, Hossein, Hajghani, Masomeh, Assar, Sepideh, Araste, Majid, Nekhei, Zohre, Sendi, Hossein, Kennedy, Derek

“…Escape mutations potentially allow viruses to avoid detection and clearance by the host immune system and may represent a mechanism through which infections…”
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M1806 Global miRNA Expression Profile of HCV Infected Human Hepatoma Cells by Steuerwald, Nury, Bennett, Kristen, Mehrab-Mohseni, Marjan, Sendi, Hossein, Bonkovsky, Herbert L

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CTL escape mutations of core protein are more frequent in strains of HBeAg negative patients with low levels of HBV DNA by Sendi, Hossein, Mehrab-Mohseni, Marjan, Shahraz, Saeid, Norder, Helene, Alavian, Seyed-Moayed, Noorinayer, Babak, Zali, Mohammad R, Pumpens, Paul, Bonkovsky, Herbert L, Magnius, Lars O

“…Abstract Background Recent studies have suggested that Cytotoxic T lymphocytes (CTL) play a key role in eliminating hepatitis B virus (HBV). Objectives We…”
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W1802 CTL Escape Mutation of Core Protein Are More Frequent in Strains of HBeAg Negative Patients with Low Viral Load by Sendi, Hossein, Mehrab-Mohseni, Marjan, Shahraz, Saeid, Norder, Helene, Alavian, Seyed-Mayed, Noorinayer, Babak, Zali, Mohammad R, Pumpens, Paul, Bonkovsky, Herbert L, Magnius, Lars

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