Search Results - "Sendera, Timothy J"

Performance evaluation of commercial short-oligonucleotide microarrays and the impact of noise in making cross-platform correlations by Shippy, Richard, Sendera, Timothy J, Lockner, Randall, Palaniappan, Chockalingam, Kaysser-Kranich, Tamma, Watts, George, Alsobrook, John

“…Despite the widespread use of microarrays, much ambiguity regarding data analysis, interpretation and correlation of the different technologies exists. There…”
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Selection of hyperfunctional siRNAs with improved potency and specificity by Wang, Xiaowei, Wang, Xiaohui, Varma, Rajeev K, Beauchamp, Lesslie, Magdaleno, Susan, Sendera, Timothy J

“…One critical step in RNA interference (RNAi) experiments is to design small interfering RNAs (siRNAs) that can greatly reduce the expression of the target…”
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Oligodeoxyribonucleotide probe accessibility on a three-dimensional DNA microarray surface and the effect of hybridization time on the accuracy of expression ratios by Dorris, David R, Nguyen, Allen, Gieser, Linn, Lockner, Randall, Lublinsky, Anna, Patterson, Marcus, Touma, Edward, Sendera, Timothy J, Elghanian, Robert, Mazumder, Abhijit

“…DNA microarrays are now routinely used to monitor the transcript levels of thousands of genes simultaneously. However, the array fabrication method,…”
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An assessment of Motorola CodeLink™ microarray performance for gene expression profiling applications by Ramakrishnan, Ramesh, Dorris, David, Lublinsky, Anna, Nguyen, Allen, Domanus, Marc, Prokhorova, Anna, Gieser, Linn, Touma, Edward, Lockner, Randall, Tata, Murthy, Zhu, Xiaomei, Patterson, Marcus, Shippy, Richard, Sendera, Timothy J., Mazumder, Abhijit

“…DNA microarrays enable users to obtain information on differences in transcript abundance on a massively parallel scale. Recently, however, data analyses have…”
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Distribution and retrograde transport of trophic factors in the central nervous system: functional implications for the treatment of neurodegenerative diseases by Mufson, E J, Kroin, J S, Sendera, T J, Sobreviela, T

“…Neurotrophins play a crucial role in the maintenance, survival and selective vulnerability of various neuronal populations within the normal and diseased…”
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Dysregulation of Gene Expression in the 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Lesioned Mouse Substantia Nigra by Miller, Renee M, Callahan, Linda M, Casaceli, Cindy, Chen, Linlin, Kiser, Gretchen L, Chui, Buena, Kaysser-Kranich, Tamma M, Sendera, Timothy J, Palaniappan, Chockalingam, Federoff, Howard J

“…Parkinson's disease pathogenesis proceeds through several phases, culminating in the loss of dopaminergic neurons of the substantia nigra (SN). Although the…”
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Combined histomorphometric and gene-expression profiling applied to toxicology by Kriete, Andres, Anderson, Mary K, Love, Brad, Freund, John, Caffrey, James J, Young, M Brook, Sendera, Timothy J, Magnuson, Scott R, Braughler, J Mark

“…We have developed a unique methodology for the combined analysis of histomorphometric and gene-expression profiles amenable to intensive data mining and…”
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Expression profiling with oligonucleotide arrays: technologies and applications for neurobiology by Sendera, Timothy J, Dorris, David, Ramakrishnan, Ramesh, Nguyen, Allen, Trakas, Dionisios, Mazumder, Abhijit

“…DNA microarrays have been used in applications ranging from the assignment of gene function to analytical uses in prognostics. However, the detection…”
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External RNA Controls Consortium: a progress report by Liu, Z.L

“…Standard controls and best practice guidelines advance acceptance of data from research, preclinical and clinical laboratories by providing a means for…”
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Morphometry of rat olfactory bulbs stained for cytochrome oxidase reveals that the entire population of glomeruli forms early in the neonatal period by Meisami, E, Sendera, T J

“…Cytochrome oxidase staining selectively highlights the synapse-rich neuropil of olfactory bulb glomeruli. Detailed morphometric enumeration of glomeruli in…”
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