Search Results - "Senapati, Dillip K."
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Structural analysis of the AICD central 12 residue peptide stretch and its interactions with metals and polyphenols, as a potential drug target for AD
Published in Journal of biomolecular structure & dynamics (01-11-2024)“…Structural analysis of the central 12 residue stretch of Amyloid precursor protein Intracellular Domain (AICD 16-27 : T-S-I-H-H-G-V-V-E-V-D-A) was carried out…”
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2
A cationic amphiphilic peptide chaperone rescues Aβ42 aggregation and cytotoxicity
Published in RSC medicinal chemistry (22-02-2023)“…Directing Aβ42 to adopt a conformation that is free from aggregation and cell toxicity is an attractive and viable strategy to design therapeutics for…”
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Journal Article -
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Deciphering the Conformations of Glutathione Oxidized Peptide: A Comparative NMR Study in Solution and Solid-State Environments
Published in Magnetic resonance in chemistry (16-10-2024)“…Glutathione (GSH) and its oxidized dimer (GSSG) play an important role in living systems as an antioxidant, balancing the presence of reactive oxygen species…”
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Proteolytically Stable ααγ-Hybrid Peptides Inhibit the Aggregation and Cytotoxicity of Aβ42
Published in ACS chemical neuroscience (20-09-2023)“…The recent approval of antibody-based therapy for targeting the clearance of amyloid plaques fuels the research in designing small molecules and peptide…”
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Journal Article -
5
A cationic amphiphilic peptide chaperone rescues Aβ 42 aggregation and cytotoxicity
Published in RSC medicinal chemistry (22-02-2023)“…Directing Aβ to adopt a conformation that is free from aggregation and cell toxicity is an attractive and viable strategy to design therapeutics for…”
Get full text
Journal Article -
6
Proteolytically Stable ααγ-Hybrid Peptides Inhibit the Aggregation and Cytotoxicity of Aβ 42
Published in ACS chemical neuroscience (20-09-2023)Get full text
Journal Article -
7
A cationic amphiphilic peptide chaperone rescues Aβ aggregation and cytotoxicity
Published in RSC medicinal chemistry (22-02-2023)“…Directing Aβ 42 to adopt a conformation that is free from aggregation and cell toxicity is an attractive and viable strategy to design therapeutics for…”
Get full text
Journal Article