Search Results - "Senapati, Arun"

40 Hz Auditory Steady-State Response Is a Pharmacodynamic Biomarker for Cortical NMDA Receptors by Sivarao, Digavalli V, Chen, Ping, Senapati, Arun, Yang, Yili, Fernandes, Alda, Benitex, Yulia, Whiterock, Valerie, Li, Yu-Wen, Ahlijanian, Michael K

“…Schizophrenia patients exhibit dysfunctional gamma oscillations in response to simple auditory stimuli or more complex cognitive tasks, a phenomenon explained…”
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Inhibition of spinal cord dorsal horn neuronal activity by electrical stimulation of the cerebellar cortex by Hagains, Christopher E, Senapati, Arun K, Huntington, Paula J, He, Ji-Wei, Peng, Yuan B

“…The cerebellum plays a major role in not only modulating motor activity, but also contributing to other functions, including nociception. The intermediate…”
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Spinal dorsal horn neuron response to mechanical stimuli is decreased by electrical stimulation of the primary motor cortex by Senapati, Arun K., Huntington, Paula J., Peng, Yuan B.

“…Motor cortex stimulation (MCS) has been used clinically as a tool for the control for central post-stroke pain and neuropathic facial pain. The underlying…”
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Hyperbaric oxygen treatment is comparable to acetylsalicylic acid treatment in an animal model of arthritis by Wilson, Hilary D, Toepfer, Virginia E, Senapati, Arun K, Wilson, Judy R, Fuchs, Perry N

“…Approximately 1 in 5 adults in the United States are affected by the pain, disability, and decreased quality of life associated with arthritis. The primary…”
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Electrical Stimulation of the Anterior Cingulate Cortex Reduces Responses of Rat Dorsal Horn Neurons to Mechanical Stimuli by Senapati, Arun K, Lagraize, Stacey C, Huntington, Paula J, Wilson, Hilary D, Fuchs, Perry N, Peng, Yuan B

“…Department of Psychology, University of Texas at Arlington, Arlington, Texas Submitted 12 January 2005; accepted in final form 11 February 2005 The anterior…”
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Near infrared and visible spectroscopic measurements to detect changes in light scattering and hemoglobin oxygen saturation from rat spinal cord during peripheral stimulation by Liu, Hanli, Radhakrishnan, Harsha, Senapati, Arun K., Hagains, Christopher E., Peswani, Disha, Mathker, Aditya, Bo Peng, Yuan

“…In this study, we investigated dynamic changes in light scattering and hemoglobin oxygen saturation ( S scO 2) on the rat spinal cord due to peripheral…”
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Electrical stimulation of the primary somatosensory cortex inhibits spinal dorsal horn neuron activity by Senapati, Arun K., Huntington, Paula J., LaGraize, Stacey C., Wilson, Hilary D., Fuchs, Perry N., Peng, Yuan B.

“…Cortical stimulation has been demonstrated to alleviate certain pain conditions. The aim of this study was to determine the responses of the spinal cord dorsal…”
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Determination of hemoglobin oxygen saturation in rat sciatic nerve by in vivo near infrared spectroscopy by Radhakrishnan, Harsha, Liu, Hanli, Senapati, Arun Kumar, Peng, Yuan Bo

“…The purpose of this study is to investigate the values of hemoglobin oxygen saturation in the sciatic nerve of the rat following spinal nerve ligation. An…”
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Discovery of Indole- and Indazole-acylsulfonamides as Potent and Selective NaV1.7 Inhibitors for the Treatment of Pain by Luo, Guanglin, Chen, Ling, Easton, Amy, Newton, Amy, Bourin, Clotilde, Shields, Eric, Mosure, Kathy, Soars, Matthew G, Knox, Ronald J, Matchett, Michele, Pieschl, Rick L, Post-Munson, Debra J, Wang, Shuya, Herrington, James, Graef, John, Newberry, Kimberly, Sivarao, Digavalli V, Senapati, Arun, Bristow, Linda J, Meanwell, Nicholas A, Thompson, Lorin A, Dzierba, Carolyn

“…3-Aryl-indole and 3-aryl-indazole derivatives were identified as potent and selective Nav1.7 inhibitors. Compound 29 was shown to be efficacious in the mouse…”
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Correction to Discovery of Indole- and Indazole-acylsulfonamides as Potent and Selective NaV1.7 Inhibitors for the Treatment of Pain by Luo, Guanglin, Chen, Ling, Easton, Amy, Newton, Amy, Bourin, Clotilde, Shields, Eric, Mosure, Kathy, Soars, Matthew G, Knox, Ronald J, Matchett, Michele, Pieschl, Rick L, Post-Munson, Debra J, Wang, Shuya, Herrington, James, Graef, John, Newberry, Kimberly, Sivarao, Digavalli V, Senapati, Arun, Bristow, Linda J, Meanwell, Nicholas A, Thompson, Lorin A, Dzierba, Carolyn

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Oxazolidinone-based allosteric modulators of mGluR5: Defining molecular switches to create a pharmacological tool box by Huang, Hong, Degnan, Andrew P., Balakrishnan, Anand, Easton, Amy, Gulianello, Michael, Huang, Yanling, Matchett, Michele, Mattson, Gail, Miller, Regina, Santone, Kenneth S., Senapati, Arun, Shields, Eric E., Sivarao, Digavalli V., Snyder, Lawrence B., Westphal, Ryan, Whiterock, Valerie J., Yang, Fukang, Bronson, Joanne J., Macor, John E.

“…[Display omitted] Herein we describe the structure activity relationships uncovered in the pursuit of an mGluR5 positive allosteric modulator (PAM) for the…”
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Correction to Discovery of Indole- and Indazole-acylsulfonamides as Potent and Selective Na V 1.7 Inhibitors for the Treatment of Pain by Luo, Guanglin, Chen, Ling, Easton, Amy, Newton, Amy, Bourin, Clotilde, Shields, Eric, Mosure, Kathy, Soars, Matthew G, Knox, Ronald J, Matchett, Michele, Pieschl, Rick L, Post-Munson, Debra J, Wang, Shuya, Herrington, James, Graef, John, Newberry, Kimberly, Sivarao, Digavalli V, Senapati, Arun, Bristow, Linda J, Meanwell, Nicholas A, Thompson, Lorin A, Dzierba, Carolyn

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Discovery of Indole- and Indazole-acylsulfonamides as Potent and Selective Na V 1.7 Inhibitors for the Treatment of Pain by Luo, Guanglin, Chen, Ling, Easton, Amy, Newton, Amy, Bourin, Clotilde, Shields, Eric, Mosure, Kathy, Soars, Matthew G, Knox, Ronald J, Matchett, Michele, Pieschl, Rick L, Post-Munson, Debra J, Wang, Shuya, Herrington, James, Graef, John, Newberry, Kimberly, Sivarao, Digavalli V, Senapati, Arun, Bristow, Linda J, Meanwell, Nicholas A, Thompson, Lorin A, Dzierba, Carolyn

“…3-Aryl-indole and 3-aryl-indazole derivatives were identified as potent and selective Na 1.7 inhibitors. Compound 29 was shown to be efficacious in the mouse…”
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Difluorocyclobutylacetylenes as positive allosteric modulators of mGluR5 with reduced bioactivation potential by Degnan, Andrew P., Maxwell, Darrell, Balakrishnan, Anand, Brown, Jeffrey M., Easton, Amy, Gulianello, Michael, Hanumegowda, Umesh, Hill-Drzewi, Melissa, Miller, Regina, Santone, Kenneth S., Senapati, Arun, Shields, Eric E., Sivarao, Digavalli V., Westphal, Ryan, Whiterock, Valerie J., Zhuo, Xiaoliang, Bronson, Joanne J., Macor, John E.

“…[Display omitted] Schizophrenia is a serious illness that affects millions of patients and has been associated with N-methyl-d-aspartate receptor (NMDAR)…”
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Discovery and Preclinical Evaluation of BMS-955829, a Potent Positive Allosteric Modulator of mGluR5 by Yang, Fukang, Snyder, Lawrence B, Balakrishnan, Anand, Brown, Jeffrey M, Sivarao, Digavalli V, Easton, Amy, Fernandes, Alda, Gulianello, Michael, Hanumegowda, Umesh M, Huang, Hong, Huang, Yanling, Jones, Kelli M, Li, Yu-Wen, Matchett, Michele, Mattson, Gail, Miller, Regina, Santone, Kenneth S, Senapati, Arun, Shields, Eric E, Simutis, Frank J, Westphal, Ryan, Whiterock, Valerie J, Bronson, Joanne J, Macor, John E, Degnan, Andrew P

“…Positive allosteric modulators (PAMs) of the metabotropic glutamate receptor subtype 5 (mGluR5) are of interest due to their potential therapeutic utility in…”
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Light scattering from rat nervous system measured intraoperatively by near-infrared reflectance spectroscopy by Radhakrishnan, Harsha, Senapati, Arun, Kashyap, Dheerendra, Peng, Yuan Bo, Liu, Hanli

“…Our goal is to quantify scattering properties of near-IR light in the rat spinal cord region and to differentiate healthy and demyelinated peripheral nerves…”
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Investigation of the periaqueductal gray matter involvement in the inhibition of dorsal horn neuron activity produced by stimulation of the motor cortex by Senapati, Arun K

“…Stimulation produced analgesia has been performed in chronic pain patients who have undergone various other procedures with little success in alleviation of…”
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Protocol: Detection of degeneration in rat sciatic nerve by in vivo near infrared spectroscopy by Senapati, Arun Kumar, Radhakrishnan, Harsha, Liu, Hanli, Peng, Yuan Bo

“…We have recently developed an optical spectroscopy technique to monitor light scattering changes of the nervous system in vivo. Near infrared (NIR)…”
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Detection of degeneration in rat sciatic nerve by in vivo near infrared spectroscopy by Senapati, Arun Kumar, Radhakrishnan, Harsha, Liu, Hanli, Peng, Yuan Bo

“…We have recently developed an optical spectroscopy technique to monitor light scattering changes of the nervous system in vivo. Near infrared (NIR)…”
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