Search Results - "Sena, Emily S"

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    Reproducibility of preclinical animal research improves with heterogeneity of study samples by Voelkl, Bernhard, Vogt, Lucile, Sena, Emily S, Würbel, Hanno

    Published in PLoS biology (01-02-2018)
    “…Single-laboratory studies conducted under highly standardized conditions are the gold standard in preclinical animal research. Using simulations based on 440…”
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    Incidence, prevalence, and predictors of chemotherapy-induced peripheral neuropathy: A systematic review and meta-analysis by Seretny, Marta, Currie, Gillian L., Sena, Emily S., Ramnarine, Sabrina, Grant, Robin, MacLeod, Malcolm R., Colvin, Leslie A., Fallon, Marie

    Published in Pain (Amsterdam) (01-12-2014)
    “…Chemotherapy-induced peripheral neuropathy (CIPN) is a disabling pain condition resulting from chemotherapy for cancer. Severe acute CIPN may require…”
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    Can animal models of disease reliably inform human studies? by van der Worp, H Bart, Howells, David W, Sena, Emily S, Porritt, Michelle J, Rewell, Sarah, O'Collins, Victoria, Macleod, Malcolm R

    Published in PLoS medicine (01-03-2010)
    “…H. Bart van der Worp and colleagues discuss the controversies and possibilities of translating the results of animal experiments into human clinical trials…”
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    Publication bias in reports of animal stroke studies leads to major overstatement of efficacy by Sena, Emily S, van der Worp, H Bart, Bath, Philip M W, Howells, David W, Macleod, Malcolm R

    Published in PLoS biology (01-03-2010)
    “…The consolidation of scientific knowledge proceeds through the interpretation and then distillation of data presented in research reports, first in review…”
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    The Automated Systematic Search Deduplicator (ASySD): a rapid, open-source, interoperable tool to remove duplicate citations in biomedical systematic reviews by Hair, Kaitlyn, Bahor, Zsanett, Macleod, Malcolm, Liao, Jing, Sena, Emily S

    Published in BMC biology (07-09-2023)
    “…Abstract Background Researchers performing high-quality systematic reviews search across multiple databases to identify relevant evidence. However, the same…”
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    Stem cell transplantation in traumatic spinal cord injury: a systematic review and meta-analysis of animal studies by Antonic, Ana, Sena, Emily S, Lees, Jennifer S, Wills, Taryn E, Skeers, Peta, Batchelor, Peter E, Macleod, Malcolm R, Howells, David W

    Published in PLoS biology (01-12-2013)
    “…Spinal cord injury (SCI) is a devastating condition that causes substantial morbidity and mortality and for which no treatments are available. Stem cells offer…”
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    Evaluation of excess significance bias in animal studies of neurological diseases by Tsilidis, Konstantinos K, Panagiotou, Orestis A, Sena, Emily S, Aretouli, Eleni, Evangelou, Evangelos, Howells, David W, Al-Shahi Salman, Rustam, Macleod, Malcolm R, Ioannidis, John P A

    Published in PLoS biology (01-07-2013)
    “…Animal studies generate valuable hypotheses that lead to the conduct of preventive or therapeutic clinical trials. We assessed whether there is evidence for…”
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    Screening for in vitro systematic reviews: a comparison of screening methods and training of a machine learning classifier by Wilson, Emma, Cruz, Florenz, Maclean, Duncan, Ghanawi, Joly, McCann, Sarah K, Brennan, Paul M, Liao, Jing, Sena, Emily S, Macleod, Malcolm

    Published in Clinical science (1979) (31-01-2023)
    “…Existing strategies to identify relevant studies for systematic review may not perform equally well across research domains. We compare four approaches based…”
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    Standardized mean differences cause funnel plot distortion in publication bias assessments by Zwetsloot, Peter-Paul, Van Der Naald, Mira, Sena, Emily S, Howells, David W, IntHout, Joanna, De Groot, Joris Ah, Chamuleau, Steven Aj, MacLeod, Malcolm R, Wever, Kimberley E

    Published in eLife (08-09-2017)
    “…Meta-analyses are increasingly used for synthesis of evidence from biomedical research, and often include an assessment of publication bias based on visual or…”
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    Olfactory Ensheathing Cell Transplantation in Experimental Spinal Cord Injury: Effect size and Reporting Bias of 62 Experimental Treatments: A Systematic Review and Meta-Analysis by Watzlawick, Ralf, Rind, Julian, Sena, Emily S, Brommer, Benedikt, Zhang, Tian, Kopp, Marcel A, Dirnagl, Ulrich, Macleod, Malcolm R, Howells, David W, Schwab, Jan M

    Published in PLoS biology (31-05-2016)
    “…Olfactory ensheathing cell (OEC) transplantation is a candidate cellular treatment approach for human spinal cord injury (SCI) due to their unique regenerative…”
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    Meta-analysis of pre-clinical studies of early decompression in acute spinal cord injury: a battle of time and pressure by Batchelor, Peter E, Wills, Taryn E, Skeers, Peta, Battistuzzo, Camila R, Macleod, Malcolm R, Howells, David W, Sena, Emily S

    Published in PloS one (23-08-2013)
    “…The use of early decompression in the management of acute spinal cord injury (SCI) remains contentious despite many pre-clinical studies demonstrating benefits…”
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