Search Results - "Sena, Diniz M."
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Ligand based conformational space studies of the μ-opioid receptor
Published in Biochimica et biophysica acta. General subjects (01-03-2021)“…G protein-coupled receptors (GPCRs) comprise a family of membrane proteins that can be activated by a variety of external factors. The μ-opioid receptor (MOR),…”
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2
Structural heterogeneity of the μ-opioid receptor’s conformational ensemble in the apo state
Published in Scientific reports (03-04-2017)“…G-protein coupled receptors (GPCRs) are the largest and most pharmaceutically relevant family of membrane proteins. Here, fully unbiased, enhanced sampling…”
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3
Modulation of the antibiotic activity against multidrug resistant strains of 4-(phenylsulfonyl) morpholine
Published in Saudi journal of biological sciences (01-01-2016)“…The compound 4-(Phenylsulfonyl) morpholine belongs to the class of sulfonamides, which are widely used in the treatment of a large number of diseases caused by…”
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4
Identification and modulatory activity assessment of 2-hydroxy-3,4,6-trimethoxyacetophenone isolated from croton anisodontus müll. Arg.(euphorbiaceae)
Published in Natural product communications (01-05-2014)“…The n-hexane extract of the stem bark of Croton anisodontus yielded 2-hydroxy-3,4,6-trimethoxyacetophenone, a well-known substance, but isolated from this…”
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5
Potentiation of antibiotic activity by chalcone (E)-1-(4′-aminophenyl)-3-(furan-2-yl)-prop-2-en-1-one against gram-positive and gram-negative MDR strains
Published in Microbial pathogenesis (01-11-2020)“…Chalcones are α,β-unsaturated ketones containing the 1,3-diarylprop-2-en-1-one framework. This study aims to evaluate the potentiation of antibacterial…”
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6
Synthesis and antibacterial activity of a new derivative of the Meldrun acid: 2,2-dimethyl-5-(4H-1,2,4-triazol-4-ylaminomethylene)-1,3-dioxane-4,6-dione (C9H10N4O4)
Published in EXCLI journal (01-01-2014)“…The discovery of new substances with proven antimicrobial activity is the current study goal of various researchers. Usage of synthetic products has grown…”
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Raman spectroscopy of topiramate under high pressure conditions
Published in Journal of Raman spectroscopy (01-03-2010)“…Topiramate is a white crystalline solid with powerful anticonvulsant activity and is used to treat epilepsy. Drug manufacturing involves various physical and…”
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8
Physicochemical and spectroscopical investigation of Pequi (Caryocar coriaceum Wittm.) pulp oil
Published in Grasas y aceites (Sevilla) (01-06-2010)“…El presente trabajo describe la caracterización físico-química del aceite de la pulpa de Caryocar coriaceum (Wittm), "pequi". La composición química fue…”
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9
Vibrational and thermal properties of crystalline topiramate
Published in Journal of the Brazilian Chemical Society (2008)“…Topiramate, a powerful anticonvulsant drug, was investigated by X-ray diffractometry, FT-Raman, FT-IR, TGA and DTA techniques as well as by DFT calculations…”
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10
Structural heterogeneity of the [mu]-opioid receptor's conformational ensemble in the apo state
Published in Scientific reports (01-04-2017)“…G-protein coupled receptors (GPCRs) are the largest and most pharmaceutically relevant family of membrane proteins. Here, fully unbiased, enhanced sampling…”
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Journal Article