Search Results - "Sen, Abhishek K."
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Development of an E. coli-based norbaeocystin production platform and evaluation of behavioral effects in rats
Published in Metabolic engineering communications (01-06-2022)“…Interest in the potential therapeutic efficacy of psilocybin and other psychedelic compounds has escalated significantly in recent years. To date, little is…”
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Unlocking the biosynthesis of psychedelic-inspired indolethylamines
Published in Trends in biochemical sciences (Amsterdam. Regular ed.) (01-03-2024)“…A recent report by Chen et al. describes the discovery of RmNMT, a highly active and promiscuous tryptamine N-methyltransferase from the cane toad, Rhinella…”
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Pharmacological and behavioural effects of tryptamines present in psilocybin‐containing mushrooms
Published in British journal of pharmacology (01-10-2024)“…Background and Purpose Demand for new antidepressants has resulted in a re‐evaluation of the therapeutic potential of psychedelic drugs. Several tryptamines…”
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Evaluation of TrpM and PsiD substrate promiscuity reveals new biocatalytic capabilities
Published in Biotechnology progress (18-06-2024)“…N-methylated tryptamines, such as the hallucinogenic natural products, psilocybin and N,N-dimethyltryptamine (DMT), are gaining interest from the medical…”
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Effect of psilocybin on decision-making and motivation in the healthy rat
Published in Behavioural brain research (25-02-2023)“…Psilocybin and its active metabolite psilocin are hallucinogenic serotonergic agonists with high affinity for several serotonin receptors. In addition to…”
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In vivo biosynthesis of N,N-dimethyltryptamine, 5-MeO-N,N-dimethyltryptamine, and bufotenine in E.coli
Published in Metabolic engineering (01-07-2023)“…N,N-dimethyltryptamine (DMT), 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) and 5-hydroxy-N,N-dimethyltryptamine (bufotenine) are psychedelic tryptamines found…”
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In vivo biosynthesis of N,N-dimethyltryptamine, 5-MeO-N,N-dimethyltryptamine, and bufotenine in E. coli
Published in Metabolic engineering (01-07-2023)Get full text
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