Search Results - "Sempoux, C."

Escalating incidence of eosinophilic esophagitis in Canton of Vaud, Switzerland, 1993–2013: a population‐based study by Giriens, B., Yan, P., Safroneeva, E., Zwahlen, M., Reinhard, A., Nydegger, A., Vavricka, S., Sempoux, C., Straumann, A., Schoepfer, A. M.

“…Background Eosinophilic esophagitis (EoE) is a chronic, inflammatory disease of the esophagus with a rapidly increasing incidence. However, population‐based…”
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Pancreatic β-cell mass in European subjects with type 2 diabetes by Rahier, J, Guiot, Y, Goebbels, R.M, Sempoux, C, Henquin, J.C

“…Decreases in both β-cell function and number can contribute to insulin deficiency in type 2 diabetes. Here, we quantified the β-cell mass in pancreas obtained…”
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Novel Histologic Scoring System for Long‐Term Allograft Fibrosis After Liver Transplantation in Children by Venturi, C., Sempoux, C., Bueno, J., Ferreres Pinas, J. C., Bourdeaux, C., Abarca‐Quinones, J., Rahier, J., Reding, R.

“…The existing systems for scoring fibrosis were not developed to evaluate transplanted livers. Our aim was to design and validate a novel fibrosis scoring…”
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Morphological Mosaicism of the Pancreatic Islets: A Novel Anatomopathological Form of Persistent Hyperinsulinemic Hypoglycemia of Infancy by Sempoux, C, Capito, C, Bellanné-Chantelot, C, Verkarre, V, de Lonlay, P, Aigrain, Y, Fekete, C, Guiot, Y, Rahier, J

“…Background: Morphological studies of the pancreas in persistent hyperinsulinemic hypoglycemia of infancy (PHHI) have focused on the diagnosis of focal vs…”
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Immune cell infiltration in colonic cancer: correlation between biopsy and surgical specimens by Bordry, N, Germann, M, Foukas, P G, Sempoux, C, Yan, P, Dormond, O, Speiser, D E, Demartines, N, Sauvain, M-O

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Pancreatic neuroendocrine tumour grading on endoscopic ultrasound-guided fine needle aspiration: high reproducibility and inter-observer agreement of the Ki-67 labelling index by Weynand, B., Borbath, I., Bernard, V., Sempoux, C., Gigot, J.-F., Hubert, C., Lannoy, V., Deprez, P. H., Jouret-Mourin, A.

“…Objectives Assessment of proliferation by the Ki‐67 labelling index (Ki67‐LI) is an important parameter of pancreatic neuroendocrine tumour (pNET) prognosis on…”
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Dynamics of Allograft Fibrosis in Pediatric Liver Transplantation by Venturi, C., Sempoux, C., Quinones, J. A., Bourdeaux, C., Hoyos, S. P., Sokal, E., Reding, R.

“…Progressive liver allograft fibrosis (LAF) is well known to occur long term, as shown by its high prevalence in late posttransplant liver biopsies (LBs). To…”
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Combination of gemcitabine and cetuximab in patients with advanced cholangiocarcinoma: a phase II study of the Belgian Group of Digestive Oncology by Borbath, I., Ceratti, A., Verslype, C., Demols, A., Delaunoit, T., Laurent, S., Deleporte, A., Vergauwe, P., Van Maanen, A., Sempoux, C., Van Cutsem, E., Van Laethem, J.L.

“…Cholangiocarcinomas are uncommon tumours with a poor prognosis, that frequently present epidermal growth factor receptor overexpression. In a multi-centre…”
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Human equilibrative nucleoside transporter 1 (hENT1) expression is a potential predictive tool for response to gemcitabine in patients with advanced cholangiocarcinoma by Borbath, I, Verbrugghe, L, Lai, R, Gigot, J.F, Humblet, Y, Piessevaux, H, Sempoux, C

“…Abstract Background Cholangiocarcinoma (CC) is a rare cancer of the liver. Surgery offers the only chance for cure. When surgery is unfeasible, chemotherapy is…”
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The malignant transformation of hepatocellular adenoma: experience of a French liver center by Sempoux, C, Blanc, J.F, Le Bail, B, Chiche, L, Balabaud, C, Bioulac-Sage, P

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ABCC8 and KCNJ11 molecular spectrum of 109 patients with diazoxide-unresponsive congenital hyperinsulinism by Bellanné-Chantelot, C, Saint-Martin, C, Ribeiro, M-J, Vaury, C, Verkarre, V, Arnoux, J-B, Valayannopoulos, V, Gobrecht, S, Sempoux, C, Rahier, J, Fournet, J-C, Jaubert, F, Aigrain, Y, Nihoul-Fékété, C, de Lonlay, P

“…Congenital hyperinsulinism (CHI) is characterised by an over secretion of insulin by the pancreatic β-cells. This condition is mostly caused by mutations in…”
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Ductular reactions provide a structural biliary network to preserve bile drainage in the CDE-model of hepatocellular chronic liver injury by Clerbaux, L.-A, Manco, R, Van Hul, N, Español-Suñer, R, Bouzin, C, Sempoux, C, Theise, N, Leclercq, I

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Pathological responses after angiogenesis or EGFR inhibitors in metastatic colorectal cancer depend on the chemotherapy backbone by Carrasco, J, Gizzi, M, Pairet, G, Lannoy, V, Lefesvre, P, Gigot, J-F, Hubert, C, Jouret-Mourin, A, Humblet, Y, Canon, J-L, Sempoux, C, Chapaux, X, Danse, E, Tinton, N, Navez, B, Van den Eynde, M

“…Background: Optimal preoperative treatment before colorectal cancer metastases (CRCM) resection remains unclear. This study evaluated pathological responses…”
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Lymph node ratio and surgical quality are strong prognostic factors of rectal cancer: results from a single referral centre by Leonard, D., Remue, C., Abbes Orabi, N., van Maanen, A., Danse, E., Dragean, A., Debetancourt, D., Humblet, Y., Jouret-Mourin, A., Maddalena, F., Medina Benites, A., Scalliet, P., Sempoux, C., Van den Eynde, M., De Schoutheete, J. C., Kartheuser, A.

“…Aim Nodal stage is a strong prognostic factor of oncological outcome of rectal cancer. To compensate for the variation in total number of harvested nodes,…”
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Phase I/II study of preoperative cetuximab, capecitabine, and external beam radiotherapy in patients with rectal cancer by Machiels, J-P, Sempoux, C, Scalliet, P, Coche, J-C, Humblet, Y, Van Cutsem, E, Kerger, J, Canon, J-L, Peeters, M, Aydin, S, Laurent, S, Kartheuser, A, Coster, B, Roels, S, Daisne, J-F, Honhon, B, Duck, L, Kirkove, C, Bonny, M-A, Haustermans, K

“…Background: To assess the safety and preliminary efficacy of concurrent radiotherapy, capecitabine, and cetuximab in the preoperative treatment of patients…”
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The PPARgamma agonist pioglitazone inhibits early neoplastic occurrence in the rat liver by Borbath, I, Leclercq, I, Moulin, P, Sempoux, C, Horsmans, Y

“…Abstract Hepatocellular carcinoma (HCC) is increasing worldwide and is the fifth main cause of cancer-related death. HCC develops on a preneoplastic organ, the…”
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P330 ACTIVATION OF INTERFERON AND NF-κB PATHWAYS IN EARLY HUMAN ALCOHOLIC LIVER DISEASE DEVELOPMENT by Stärkel, P, Lanthier, N, De Saeger, C, Sempoux, C, Leclercq, I.A, Horsmans, Y

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Limited therapeutic efficacy of pioglitazone on progression of hepatic fibrosis in rats by Leclercq, I A, Sempoux, C, Stärkel, P, Horsmans, Y

“…Aim: Peroxisome proliferator activated receptor γ (PPARγ) agonists have been shown to prevent hepatic fibrosis in rodents. We evaluated the therapeutic…”
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Need for objective and reproducible criteria in histopathological assessment of total mesorectal excision specimens: lessons from a national improvement project by Demetter, P., Vandendael, T., Sempoux, C., Ectors, N., Cuvelier, C. A., Nagy, N., Hoorens, A., Jouret-Mourin, A.

“…Aim Data on quality control of the pathologic evaluation of total mesorectal excision (TME) specimens are scarce. We aimed to assess differences between…”
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Propylthiouracyl-induced severe liver toxicity： An indication for alanine aminotransferase monitoring by Benyounes, M, Sempoux, C, Daumerie, C, Rahier, J, Geubel, A P

“…Propylthiouracyl （PTU）-related liver toxicity is likely to occur in about 1% of treated patients. In case of acute or subacute hepatitis, liver failure may…”
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