Search Results - "Semple, C. A. M"

A bioinformatic screen for novel A–I RNA editing sites reveals recoding editing in BC10 by Clutterbuck, D. R., Leroy, A., O'Connell, M. A., Semple, C. A. M.

“…Motivation: Recent studies have demonstrated widespread adenosine–inosine RNA editing in non-coding sequence. However, the extent of editing in coding…”
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In silico identification of transcripts and SNPs from a region of 4p linked with bipolar affective disorder by Semple, C. A. M., Morris, S. W., Porteous, D. J., Evans, K. L.

“…Contact: c.semple@hgu.mrc.ac.uk Availability: Files containing the accession numbers of all EST clusters and SNPs from this study are available at…”
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Physical mapping: integrating computational and molecular genetic data by LE HELLARD, S., SEMPLE, C. A. M., MORRIS, S. W., PORTEOUS, D. J., EVANS, K. L.

“…A crucial step beyond the identification of genetic linkage of a disease to a chromosomal region is the production of a physical map that will allow the…”
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BiForce Toolbox: powerful high-throughput computational analysis of gene-gene interactions in genome-wide association studies by Gyenesei, Attila, Moody, Jonathan, Laiho, Asta, Semple, Colin A M, Haley, Chris S, Wei, Wen-Hua

“…Genome-wide association studies (GWAS) have discovered many loci associated with common disease and quantitative traits. However, most GWAS have not studied…”
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Meet the parents: bioinformatics and computational biology by Semple, C A M

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Beta-defensin evolution: selection complexity and clues for residues of functional importance by Semple, C A M, Taylor, K, Eastwood, H, Barran, P E, Dorin, J R

“…We have examined the evolution of the genes at the major human beta-defensin locus and the orthologous loci in a range of other primates and mammals. For the…”
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Chromosomal Location and Genomic Structure of the Human Translin-Associated Factor X Gene (TRAX; TSNAX) Revealed by Intergenic Splicing to DISC1, a Gene Disrupted by a Translocation Segregating with Schizophrenia by Millar, J.Kirsty, Christie, Sheila, Semple, Colin A.M., Porteous, David J.

“…Two candidate genes, DISC1 and DISC2 on chromosome 1, are disrupted by a translocation that segregates with major psychiatric illness. Several DISC1…”
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Identification of Genes from a Schizophrenia-Linked Translocation Breakpoint Region by Semple, C.A.M., Devon, R.S., Le Hellard, S., Porteous, D.J.

“…The translocation t(1:11)(q42.1,q14.3) has previously been found to be linked with schizophrenia. Genes present at the chromosome 1 breakpoint have been…”
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Physical mapping: integrating computational and molecular genetic data by HELLARD, S., SEMPLE, C. A. M., MORRIS, S. W., PORTEOUS, D. J., EVANS, K. L.

“…A crucial step beyond the identification of genetic linkage of a disease to a chromosomal region is the production of a physical map that will allow the…”
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