Search Results - "Semova, Ivana"
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Microbiota Regulate Intestinal Absorption and Metabolism of Fatty Acids in the Zebrafish
Published in Cell host & microbe (13-09-2012)“…Regulation of intestinal dietary fat absorption is critical to maintaining energy balance. While intestinal microbiota clearly impact the host’s energy…”
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FoxO1 Is Required for Most of the Metabolic and Hormonal Perturbations Produced by Hepatic Insulin Receptor Deletion in Male Mice
Published in Endocrinology (Philadelphia) (01-03-2018)“…Abstract Insulin coordinates the complex response to feeding, affecting numerous metabolic and hormonal pathways. Forkhead box protein O1 (FoxO1) is one of…”
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3
Mice lacking lipid droplet-associated hydrolase, a gene linked to human prostate cancer, have normal cholesterol ester metabolism
Published in Journal of lipid research (01-01-2017)“…Variations in the gene LDAH (C2ORF43), which encodes lipid droplet-associated hydrolase (LDAH), are among few loci associated with human prostate cancer…”
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4
Patterns and Scales in Gastrointestinal Microbial Ecology
Published in Gastroenterology (New York, N.Y. 1943) (01-05-2009)“…The body surfaces of humans and other animals are colonized at birth by microorganisms. The majority of microbial residents on the human body exist within…”
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5
Triglycerides in Nonalcoholic Fatty Liver Disease: Guilty Until Proven Innocent
Published in Trends in pharmacological sciences (Regular ed.) (01-03-2021)“…End-stage liver disease (ESLD) is a rare but often fatal complication of nonalcoholic fatty liver disease (NAFLD). In NAFLD, insulin resistance, which is…”
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6
Methods for generating and colonizing gnotobiotic zebrafish
Published in Nature protocols (01-12-2008)“…Vertebrates are colonized at birth by complex and dynamic communities of microorganisms that can contribute significantly to host health and disease. The…”
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7
Insulin Prevents Hypercholesterolemia by Suppressing 12α-Hydroxylated Bile Acids
Published in Circulation (New York, N.Y.) (29-03-2022)“…The risk of cardiovascular disease in type 1 diabetes remains extremely high, despite marked advances in blood glucose control and even the widespread use of…”
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8
Insulin Prevents Hypercholesterolemia by Suppressing 12a-Hydroxylated Bile Acid Production
Published in Circulation (New York, N.Y.) (28-02-2022)Get full text
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9
Fructose and glucose can regulate mammalian target of rapamycin complex 1 and lipogenic gene expression via distinct pathways
Published in The Journal of biological chemistry (09-02-2018)“…Although calorically equivalent to glucose, fructose appears to be more lipogenic, promoting dyslipidemia, fatty liver disease, cardiovascular disease, and…”
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10
Microbiota and dietary nutrients regulate digestive enzyme activity in the zebrafish intestine
Published in The FASEB journal (01-04-2010)“…The microbial community residing in the intestine (microbiota) is an important environmental factor regulating nutrient metabolism and energy storage. An…”
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Markers of cholesterol synthesis are elevated in adolescents and young adults with type 2 diabetes
Published in Pediatric diabetes (01-11-2020)“…Background Changes in cholesterol absorption and cholesterol synthesis may promote dyslipidemia and cardiovascular disease in individuals with type 2 diabetes…”
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Type 1 diabetes is associated with an increase in cholesterol absorption markers but a decrease in cholesterol synthesis markers in a young adult population
Published in Journal of clinical lipidology (01-11-2019)“…To optimize treatment and prevent cardiovascular disease in subjects with type 1 diabetes, it is important to determine how cholesterol metabolism changes with…”
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13
Transcriptional Integration of Distinct Microbial and Nutritional Signals by the Small Intestinal Epithelium
Published in Cellular and molecular gastroenterology and hepatology (01-01-2022)“…The intestine constantly interprets and adapts to complex combinations of dietary and microbial stimuli. However, the transcriptional strategies by which the…”
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The role of gut microbiota and diet in lipid metabolism
Published 2012“…The large community of microorganisms in the intestine (microbiota) has been identified as an additional metabolic organ in our body. However, the microbial…”
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