Search Results - "Seminoff, Kelsey"

Pharmacokinetics of grapiprant and effects on TNF‐alpha concentrations following oral administration to horses by Hoffmann, Silke L., Seminoff, Kelsey, McKemie, Daniel S., Kass, Philip H., Knych, Heather K.

“…Grapiprant is a prostaglandin E2 receptor antagonist that has been found to be an effective anti‐inflammatory in dogs and that is devoid of some of the adverse…”
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Pharmacokinetics and anti‐inflammatory effects of flunixin meglumine as a sole agent and in combination with phenylbutazone in exercised Thoroughbred horses by Knych, Heather K., Arthur, Rick M., McKemie, Daniel S., Baden, Russell W., Seminoff, Kelsey, Kass, Philip H.

“…Background Flunixin meglumine (FM) and phenylbutazone (PBZ) are potent anti‐inflammatory agents and as such their potential to mask injuries that would…”
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Detection and pharmacokinetics of grapiprant following oral administration to exercised Thoroughbred horses by Knych, Heather K., Seminoff, Kelsey, McKemie, Dan S.

“…Traditional therapeutic options for the treatment of lameness associated with inflammation in performance horses include administration of cyclooxygenase…”
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Preliminary study of the pharmacokinetics, tissue distribution, and behavioral and select physiological effects of morphine 6-glucuronide (M6G) following intravenous administration to horses by Hamamoto-Hardman, Briana D., Steffey, Eugene P., Seminoff, Kelsey, McKemie, Daniel S., Kass, Philip, Knych, Heather K.

“…Although morphine has demonstrated antinociceptive effects in horses, its administration has been associated with dose-dependent adverse effects. In humans and…”
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Phenylbutazone blood and urine concentrations, pharmacokinetics, and effects on biomarkers of inflammation in horses following intravenous and oral administration of clinical doses by Knych, Heather K., Arthur, Rick M., McKemie, Dan S., Seminoff, Kelsey, Hamamoto‐Hardman, Briana, Kass, Philip H.

“…Phenylbutazone (PBZ) is a potent mon‐steroidal anti‐inflammatory drug used commonly in performance horses. The objectives of the current study were to describe…”
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L‐ and D‐threo ethylphenidate concentrations, pharmacokinetics, and pharmacodynamics in horses by Knych, Heather K., McKemie, Dan S., Seminoff, Kelsey, Hartmann, Petra, Hovda, Lynn, Benson, Dionne

“…Ethylphenidate is a psychostimulant and analog of the commonly prescribed compound, methylphenidate (Ritalin®). There are a limited number of studies…”
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