Search Results - "Seminars in immunopathology"

Pathogenic human coronavirus infections: causes and consequences of cytokine storm and immunopathology by Channappanavar, Rudragouda, Perlman, Stanley

“…Human coronaviruses (hCoVs) can be divided into low pathogenic and highly pathogenic coronaviruses. The low pathogenic CoVs infect the upper respiratory tract…”
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Cytokine storm and sepsis disease pathogenesis by Chousterman, Benjamin G., Swirski, Filip K., Weber, Georg F.

“…Infectious diseases are a leading cause of death worldwide. Sepsis is a severe clinical syndrome related to the host response to infection. The severity of…”
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The pathogenicity of Th17 cells in autoimmune diseases by Yasuda, Keiko, Takeuchi, Yusuke, Hirota, Keiji

“…IL-17-producing T helper (Th17) cells have been implicated in the pathogenesis of many inflammatory and autoimmune diseases. Targeting the effector cytokines…”
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Asthma epidemiology and risk factors by Stern, Jessica, Pier, Jennifer, Litonjua, Augusto A.

“…Asthma is a clinical syndrome that affects all age groups. Asthma prevalence worldwide has seen a rapid increase in the latter part of the last century. Recent…”
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Dysbiosis of the gut and lung microbiome has a role in asthma by Hufnagl, Karin, Pali-Schöll, Isabella, Roth-Walter, Franziska, Jensen-Jarolim, Erika

“…Worldwide 300 million children and adults are affected by asthma. The development of asthma is influenced by environmental and other exogenous factors…”
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Sex differences in vaccine-induced humoral immunity by Fischinger, Stephanie, Boudreau, Carolyn M., Butler, Audrey L., Streeck, Hendrik, Alter, Galit

“…Vaccines are among the most impactful public health interventions, preventing millions of new infections and deaths annually worldwide. However, emerging data…”
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The interplay between immunosenescence and age-related diseases by Barbé-Tuana, Florencia, Funchal, Giselle, Schmitz, Carine Raquel Richter, Maurmann, Rafael Moura, Bauer, Moisés E.

“…The aging immune system (immunosenescence) has been implicated with increased morbidity and mortality in the elderly. Of note, T cell aging and low-grade…”
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CD8+ T cell exhaustion by Kurachi, Makoto

“…CD8 + T cells are important for the protective immunity against intracellular pathogens and tumor. In the case of chronic infection or cancer, CD8 + T cells…”
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Molecular interactions at the surface of extracellular vesicles by Buzás, Edit I., Tóth, Eszter Á., Sódar, Barbara W., Szabó-Taylor, Katalin É.

“…Extracellular vesicles such as exosomes, microvesicles, apoptotic bodies, and large oncosomes have been shown to participate in a wide variety of biological…”
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Preterm birth and sustained inflammation: consequences for the neonate by Humberg, Alexander, Fortmann, Ingmar, Siller, Bastian, Kopp, Matthias Volkmar, Herting, Egbert, Göpel, Wolfgang, Härtel, Christoph

“…Almost half of all preterm births are caused or triggered by an inflammatory process at the feto-maternal interface resulting in preterm labor or rupture of…”
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Inhibiting IDO pathways to treat cancer: lessons from the ECHO-301 trial and beyond by Muller, Alexander J., Manfredi, Mark G., Zakharia, Yousef, Prendergast, George C.

“…With immunotherapy enjoying a rapid resurgence based on the achievement of durable remissions in some patients with agents that derepress immune function,…”
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The gut microbiota and inflammatory bowel disease by Matsuoka, Katsuyoshi, Kanai, Takanori

“…Inflammatory bowel disease (IBD) is a chronic and relapsing inflammatory disorder of the gut. Although the precise cause of IBD remains unknown, the most…”
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Hemostasis, endothelial stress, inflammation, and the metabolic syndrome by Grandl, Gerald, Wolfrum, Christian

“…Obesity and the metabolic syndrome (MS) are two of the pressing healthcare problems of our time. The MS is defined as increased abdominal obesity in concert…”
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Skin neurogenic inflammation by Choi, Jae Eun, Di Nardo, Anna

“…The epidermis closely interacts with nerve endings, and both epidermis and nerves produce substances for mutual sustenance. Neuropeptides, like substance P…”
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The host immune response in respiratory virus infection: balancing virus clearance and immunopathology by Newton, Amy H., Cardani, Amber, Braciale, Thomas J.

“…The respiratory tract is constantly exposed to the external environment, and therefore, must be equipped to respond to and eliminate pathogens. Viral clearance…”
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Inflammatory Responses After Ischemic Stroke by DeLong, Jonathan Howard, Ohashi, Sarah Naomi, O’Connor, Kevin Charles, Sansing, Lauren Hachmann

“…Ischemic stroke generates an immune response that contributes to neuronal loss as well as tissue repair. This is a complex process involving a range of cell…”
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Neurogenic inflammation and its role in migraine by Ramachandran, Roshni

“…The etiology of migraine pain involves sensitized meningeal afferents that densely innervate the dural vasculature. These afferents, with their cell bodies…”
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Role of viruses in asthma by Jartti, Tuomas, Bønnelykke, Klaus, Elenius, Varpu, Feleszko, Wojciech

“…Respiratory viral infections are the most important triggers of asthma exacerbations. Rhinovirus (RV), the common cold virus, is clearly the most prevalent…”
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The microgenderome revealed: sex differences in bidirectional interactions between the microbiota, hormones, immunity and disease susceptibility by Vemuri, Ravichandra, Sylvia, Kristyn E., Klein, Sabra L., Forster, Samuel C., Plebanski, Magdalena, Eri, Raj, Flanagan, Katie L.

“…Sex differences in immunity are well described in the literature and thought to be mainly driven by sex hormones and sex-linked immune response genes. The…”
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Selected cytokine pathways in rheumatoid arthritis by Noack, Mélissa, Miossec, Pierre

“…Rheumatoid arthritis (RA) is a chronic inflammatory disease leading to joint destruction. Cytokines play a key role in its pathogenesis. They contribute to the…”
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