Search Results - "Semiglazov, Vladimir F"

Pegylated Liposomal Doxorubicin Plus Docetaxel Significantly Improves Time to Progression Without Additive Cardiotoxicity Compared With Docetaxel Monotherapy in Patients With Advanced Breast Cancer Previously Treated With Neoadjuvant-Adjuvant Anthracycline Therapy: Results From a Randomized Phase III Study by SPARANO, Joseph A, MAKHSON, Anatoly N, ZHUANG, Sen H, LIANG XIU, ZHILONG YUAN, RACKOFF, Wayne R, SEMIGLAZOV, Vladimir F, TJULANDIN, Sergei A, BALASHOVA, Olga I, BONDARENKO, Igor N, BOGDANOVA, Natalia V, MANIKHAS, George M, OLIYNYCHENKO, Gennadiy P, CHATIKHINE, Valery A

“…To determine whether the combination of pegylated liposomal doxorubicin (PLD) and docetaxel significantly prolongs time to disease progression compared with…”
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Mixed epithelial/mesenchymal metaplastic carcinoma (carcinosarcoma) of the breast in BRCA1 carrier by Suspitsin, Evgeny N., Sokolenko, Anna P., Voskresenskiy, Dmitry A., Ivantsov, Alexandr O., Shelehova, Kseniya V., Klimashevskiy, Valery F., Matsko, Dmitry E., Semiglazov, Vladimir F., Imyanitov, Evgeny N.

“…This case report describes a 35-year-old woman who was diagnosed with mixed epithelial/mesenchymal metaplastic carcinoma (carcinosarcoma) of the breast…”
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Founder mutations in early-onset, familial and bilateral breast cancer patients from Russia by Sokolenko, Anna P, Rozanov, Maxim E, Mitiushkina, Natalia V, Sherina, Natalia Yu, Iyevleva, Aglaya G, Chekmariova, Elena V, Buslov, Konstantin G, Shilov, Evgeny S, Togo, Alexandr V, Bit-Sava, Elena M, Voskresenskiy, Dmitry A, Chagunava, Oleg L, Devilee, Peter, Cornelisse, Cees, Semiglazov, Vladimir F, Imyanitov, Evgeny N

“…Previous studies indicate that founder mutations may play a noticeable role in breast cancer (BC) predisposition in Russia. Here we performed a systematic…”
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Phase 2 randomized trial of primary endocrine therapy versus chemotherapy in postmenopausal patients with estrogen receptor‐positive breast cancer by Semiglazov, Vladimir F., Semiglazov, Vladislav V., Dashyan, Garik A., Ziltsova, Elena K., Ivanov, Vadim G., Bozhok, Alla A., Melnikova, Olga A., Paltuev, Ruslan M., Kletzel, Alexander, Berstein, Lev M.

“…BACKGROUND. Few studies have compared primary neoadjuvant endocrine therapy with neoadjuvant chemotherapy in breast cancer patients. The need for preoperative…”
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High prevalence and breast cancer predisposing role of the BLM c.1642 C>T (Q548X) mutation in Russia by Sokolenko, Anna P., Iyevleva, Aglaya G., Preobrazhenskaya, Elena V., Mitiushkina, Nathalia V., Abysheva, Svetlana N., Suspitsin, Evgeny N., Kuligina, Ekatherina Sh, Gorodnova, Tatiana V., Pfeifer, Werner, Togo, Alexandr V., Turkevich, Elena A., Ivantsov, Alexandr O., Voskresenskiy, Dmitry V., Dolmatov, Georgy D., Bit-Sava, Elena M., Matsko, Dmitry E., Semiglazov, Vladimir F., Fichtner, Iduna, Larionov, Alexey A., Kuznetsov, Sergey G., Antoniou, Antonis C., Imyanitov, Evgeny N.

“…The BLM gene belongs to the RecQ helicase family and has been implicated in the maintenance of genomic stability. Its homozygous germline inactivation causes…”
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Trabectedin as a Single-Agent Treatment of Advanced Breast Cancer After Anthracycline and Taxane Treatment: A Multicenter, Randomized, Phase II Study Comparing 2 Administration Regimens by Goldstein, Lori J, Gurtler, Jayne, Del Prete, Salvatore A, Tjulandin, Sergei, Semiglazov, Vladimir F, Bayever, Eliel, Michiels, Bart

“…Micro-Abstract In this study we assessed efficacy and safety of trabectedin 3-hour infusion at 1.3 mg/m2 once every 3 weeks (a) or 0.58 mg/m2 weekly for 3 of 4…”
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A phase III randomized equivalence study of biosimilar filgrastim versus Amgen filgrastim in patients receiving myelosuppressive chemotherapy for breast cancer by Waller, Cornelius F, Semiglazov, Vladimir F, Tjulandin, Sergei, Bentsion, Dmitry, Chan, Stephen, Challand, Rodeina

“…Filgrastim was developed to treat chemotherapy-induced neutropenia. This phase III study was designed to demonstrate bioequivalence of Amgen filgrastim and a…”
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More favorable progesterone receptor phenotype of breast cancer in diabetics treated with metformin by Berstein, Lev M., Boyarkina, Marina P., Tsyrlina, Evgenia V., Turkevich, Elena A., Semiglazov, Vladimir F.

“…The coexistence of type 2 diabetes with breast cancer may result in poorer cancer-related survival due to a number of mediating factors including an alteration…”
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A phase II, randomized, blinded study of the farnesyltransferase inhibitor tipifarnib combined with letrozole in the treatment of advanced breast cancer after antiestrogen therapy by Johnston, Stephen R. D., Semiglazov, Vladimir F., Manikhas, George M., Spaeth, Dominique, Romieu, Gilles, Dodwell, David J., Wardley, Andrew M., Neven, Patrick, Bessems, Annick, Park, Youn C., De Porre, Peter M., Perez Ruixo, Juan J., Howes, Angela J.

“…Background This study assessed the clinical efficacy of the farnesyltransferase inhibitor, tipifarnib, combined with letrozole in patients with advanced breast…”
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Large family with both parents affected by distinct BRCA1 mutations: implications for genetic testing by Sokolenko, Anna P, Voskresenskiy, Dmitry A, Iyevleva, Aglaya G, Bit-Sava, Elena M, Gutkina, Nadezhda I, Anisimenko, Maxim S, Yu Sherina, Nathalia, Mitiushkina, Nathalia V, Ulibina, Yulia M, Yatsuk, Olga S, Zaitseva, Olga A, Suspitsin, Evgeny N, Togo, Alexandr V, Pospelov, Valery A, Kovalenko, Sergey P, Semiglazov, Vladimir F, Imyanitov, Evgeny N

“…Although the probability of both parents being affected by BRCA1 mutations is not negligible, such families have not been systematically described in the…”
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High frequency of BRCA1 5382insC mutation in Russian breast cancer patients by Sokolenko, Anna P., Mitiushkina, Natalia V., Buslov, Konstantin G., Bit-Sava, Elena M., Iyevleva, Aglaya G., Chekmariova, Elena V., Kuligina, Ekatherina Sh, Ulibina, Yulia M., Rozanov, Maxim E., Suspitsin, Evgeny N., Matsko, Dmitry E., Chagunava, Oleg L., Trofimov, Dmitry Yu, Devilee, Peter, Cornelisse, Cees, Togo, Alexandr V., Semiglazov, Vladimir F., Imyanitov, Evgeny N.

“…BRCA1 5382insC variant was repeatedly detected in Jewish breast cancer (BC) families residing in USA and Israel as well as in non-Jewish familial BC patients…”
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NBS1 657del5 mutation may contribute only to a limited fraction of breast cancer cases in Russia by Buslov, Konstantin G., Iyevleva, Aglaya G., Chekmariova, Elena V., Suspitsin, Evgeny N., Togo, Alexandr V., Kuligina, Ekatherina Sh, Sokolenko, Anna P., Matsko, Dmitry E., Turkevich, Elena A., Lazareva, Yulia R., Chagunava, Oleg L., Bit‐Sava, Elena M., Semiglazov, Vladimir F., Devilee, Peter, Cornelisse, Cees, Hanson, Kaido P., Imyanitov, Evgeny N.

“…The gene for Nijmegen chromosomal breakage syndrome (NBS1) plays a role in a variety of processes protecting chromosomal stability. Recently, it was suggested…”
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Signs of proinflammatory/genotoxic switch (adipogenotoxicosis) in mammary fat of breast cancer patients: Role of menopausal status, estrogens and hyperglycemia by Berstein, Lev M., Kovalevskij, Anatolij Y., Poroshina, Tatjana E., Kotov, Alexander V., Kovalenko, Irina G., Tsyrlina, Evgenia V., Leenman, Elena E., Revskoy, Sergey Y., Semiglazov, Vladimir F., Pozharisski, Kazimir M.

“…The abundance of fat tissue surrounding normal and malignant epithelial mammary cells raises the questions whether such “adipose milieu” is important in the…”
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CHEK2 1100delC mutation is frequent among Russian breast cancer patients by Chekmariova, Elena V, Sokolenko, Anna P, Buslov, Konstantin G, Iyevleva, Aglaya G, Ulibina, Yulia M, Rozanov, Maxim E, Mitiushkina, Natalia V, Togo, Alexandr V, Matsko, Dmitry E, Voskresenskiy, Dmitry A, Chagunava, Oleg L, Devilee, Peter, Cornelisse, Cees, Semiglazov, Vladimir F, Imyanitov, Evgeny N

“…This study was aimed to assess the role of CHEK2 1100delC mutation in breast cancer (BC) predisposition in Russia. The 1100delC allele was detected in 14/660…”
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Distribution of Coding Apoptotic Gene Polymorphisms in Women with Extreme Phenotypes of Breast Cancer Predisposition and Tolerance by Ulybina, Yulia M, Kuligina, Ekatherina S, Mitiushkina, Nathalia V, Sherina, Nathalia Y, Baholdin, Dmitry V, Voskresenskiy, Dmitry A, Polyakov, Igor S, Togo, Alexandr V, Semiglazov, Vladimir F, Imyanitov, Evgeny N

“…Aims and background Comparison of subjects with extreme phenotypes of cancer susceptibility and tolerance allows to detect low-penetrance gene-disease…”
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Breast cancer by Zhukova, Liudmila G., Andreeva, Iuliia I., Zavalishina, Larisa E., Zakiriakhodzhaev, Aziz D., Koroleva, Irina A., Nazarenko, Aleksei V., Paltuev, Ruslan M., Parokonnaia, Anastasiia A., Petrovskii, Aleksandr V., Portnoi, Sergei M., Semiglazov, Vladimir F., Semiglazova, Tatiana I., Stenina, Marina B., Stepanova, Aleksandra M., Trofimova, Oxana P., Tyulyandin, Sergey A., Frank, Georgii A., Frolova, Mona A., Shatova, Iuliana S., Nevol’skikh, Aleksei A., Ivanov, Sergei A., Khailova, Zhanna V., Gevorkian, Tigran G.

“…Breast cancer (BC) is a malignant tumor originating from the epithelium of the breast tissue. There is no single etiological factor in the development of…”
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Breast cancer by Liudmila G. Zhukova, Iuliia I. Andreeva, Larisa E. Zavalishina, Aziz D. Zakiriakhodzhaev, Irina A. Koroleva, Aleksei V. Nazarenko, Ruslan M. Paltuev, Anastasiia A. Parokonnaia, Aleksandr V. Petrovskii, Sergei M. Portnoi, Vladimir F. Semiglazov, Tatiana I. Semiglazova, Marina B. Stenina, Aleksandra M. Stepanova, Oxana P. Trofimova, Sergey A. Tyulyandin, Georgii A. Frank, Mona A. Frolova, Iuliana S. Shatova, Aleksei A. Nevol’skikh, Sergei A. Ivanov, Zhanna V. Khailova, Tigran G. Gevorkian

“…Breast cancer (BC) is a malignant tumor originating from the epithelium of the breast tissue. There is no single etiological factor in the development of…”
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Distribution of coding apoptotic gene polymorphisms in women with extreme phenotypes of breast cancer predisposition and tolerance by Ulybina, Yulia M, Kuligina, Ekatherina S, Mitiushkina, Nathalia V, Sherina, Nathalia Y, Baholdin, Dmitry V, Voskresenskiy, Dmitry A, Polyakov, Igor S, Togo, Alexandr V, Semiglazov, Vladimir F, Imyanitov, Evgeny N

“…AIMS AND BACKGROUNDComparison of subjects with extreme phenotypes of cancer susceptibility and tolerance allows to detect low-penetrance gene-disease…”
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High prevalence and breast cancer predisposing role of the BLM c.1642 C>T (Q548X) mutation in Russia by SOKOLENKO, Anna P, IYEVLEVA, Aglaya G, TURKEVICH, Elena A, IVANTSOV, Alexandr O, VOSKRESENSKIY, Dmitry V, DOLMATOV, Georgy D, BIT-SAVA, Elena M, MATSKO, Dmitry E, SEMIGLAZOV, Vladimir F, FICHTNER, Iduna, LARIONOV, Alexey A, KUZNETSOV, Sergey G, PREOBRAZHENSKAYA, Elena V, ANTONIOU, Antonis C, IMYANITOV, Evgeny N, MITIUSHKINA, Nathalia V, ABYSHEVA, Svetlana N, SUSPITSIN, Evgeny N, KULIGINA, Ekatherina Sh, GORODNOVA, Tatiana V, PFEIFER, Werner, TOGO, Alexandr V

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High frequency of BRCA1 5382insC mutation in Russian breast cancer patients by SOKOLENKO, Anna P, MITIUSHKINA, Natalia V, MATSKO, Dmitry E, CHAGUNAVA, Oleg L, TROFIMOV, Dmitry Yu, DEUILEE, Peter, CORNELISSE, Cees, TOGO, Alexandr V, SEMIGLAZOV, Vladimir F, IMYANITOV, Eugeny N, BUSLOV, Konstantin G, BIT-SAVA, Elena M, IYEVLEVA, Aglaya G, CHEKMARIOVA, Elena V, KULIGINA, Ekatherina Sh, ULIBINA, Yulia M, ROZANOV, Maxim E, SUSPITSIN, Eugeny N

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