Search Results - "Semenchenko, Kostyantyn"

XRP44X, an Inhibitor of Ras/Erk Activation of the Transcription Factor Elk3, Inhibits Tumour Growth and Metastasis in Mice by Semenchenko, Kostyantyn, Wasylyk, Christine, Cheung, Henry, Tourrette, Yves, Maas, Peter, Schalken, Jack A, van der Pluijm, Gabri, Wasylyk, Bohdan

“…Transcription factors have an important role in cancer but are difficult targets for the development of tumour therapies. These factors include the Ets family,…”
Get full text

Tubulin tyrosine ligase like 12, a TTLL family member with SET- and TTL-like domains and roles in histone and tubulin modifications and mitosis by Brants, Jan, Semenchenko, Kostyantyn, Wasylyk, Christine, Robert, Aude, Carles, Annaick, Zambrano, Alberto, Pradeau-Aubreton, Karine, Birck, Catherine, Schalken, Jack A, Poch, Olivier, de Mey, Jan, Wasylyk, Bohdan

“…hTTLL12 is a member of the tubulin tyrosine ligase (TTL) family that is highly conserved in phylogeny. It has both SET-like and TTL-like domains, suggesting…”
Get full text

Abstract 2448: Modeling the mechanisms behind the biphasic expression of the PTK7 tyrosine kinase receptor in colorectal cancer by Ganier, Laetitia, Aulas, Anais, Cabaud, Olivier, Lopresti, Alexia, Semenchenko, Kostyantyn, Finetti, Pascal, Gilabert, Marine, Goncalves, Anthony, Acquaviva, Claire, Birnbaum, Daniel, Mamessier, Emilie, Borg, Jean-Paul

“…Abstract Colorectal cancer (CRC) is the second deadliest cancer worldwide. Discovery of new biomarkers and therapeutic targets is thus essential (PMID:…”
Get full text

Crosstalk between Mdm2, p53 and HIF1-α: distinct responses to oxygen stress and implications for tumour hypoxia by Robertson, E Douglas, Semenchenko, Kostyantyn, Wasylyk, Bohdan

“…The E3 ubiquitin ligase Mdm2 regulates two transcription factors, p53 and HIF1α, which appear to be tailored towards different and specific roles within the…”
Get more information