Search Results - "Sembulingam, Tamilzhalagan"

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    Amplified 7q21‐22 gene MCM7 and its intronic miR‐25 suppress COL1A2 associated genes to sustain intestinal gastric cancer features by Tamilzhalagan, Sembulingam, Rathinam, Dhanasekaran, Ganesan, Kumaresan

    Published in Molecular carcinogenesis (01-06-2017)
    “…Frequent amplification of 7q21‐22 genomic region is known in gastric cancer. Multiple genes including SHFM1, MCM7, and COL1A2 were reported to be the potential…”
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    Journal Article
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    Juxtaposed genes in 7q21‐22 amplicon contribute for two major gastric cancer sub‐Types by mutual exclusive expression by Tamilzhalagan, Sembulingam, Muthuswami, Muthulakshmi, Ganesan, Kumaresan

    Published in Molecular carcinogenesis (01-04-2017)
    “…Genomic Copy Number Variations (CNV) and the associated gene signatures are useful for cancer prognosis, diagnosis, and targeted therapeutics. Earlier, 7q21‐22…”
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    Journal Article
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    Upregulated, 7q21–22 amplicon candidate gene SHFM1 confers oncogenic advantage by suppressing p53 function in gastric cancer by Tamilzhalagan, Sembulingam, Muthuswami, Muthulakshmi, Periasamy, Jayaprakash, Lee, Ming Hui, Rha, Sun Young, Tan, Patrick, Ganesan, Kumaresan

    Published in Cellular signalling (01-06-2015)
    “…Chromosomal aberrations are hallmarks of cancers and the locus of frequent genomic amplifications often harbors key cancer driver genes. Many genomic amplicons…”
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    Journal Article
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